Pharmacological Considerations In Gerontology

Underscores the complexity of prescribing drugs for older adults while providing state-of-the-art guidelines for safe patient care An evidence-based, quick-access reference for adult gerontology nurse practitioners and related healthcare providers, this text describes a holistic, patient-centered approach to prescribing drugs to older adults. Comprehensive yet concise writing distills timely guidance on the complexities of safely prescribing to this unique population. This book opens with physiologic changes and assessment considerations for older adults, followed by a discussion of pharmacokinetics and pharmacodynamics, then a final section on guidelines for drug selection, drug interactions, and multimorbidities. Each chapter presents information in a consistent, easy-to-read template. Patient Care Pearls alert readers to crucial information and relevant case studies with examples of inappropriate medical prescribing provide context for drug delivery. Key points and chapter summaries help reinforce information. Additional features include the provision of guidelines for psychotropic medications in LTC facilities, special considerations for frail older adults, and the role of pharmacists as a resource for other practitioners. Key Features: Decision-making guidance on prescribing practices in varied settings Discusses in depth physiological considerations including multimorbidity and polypharmacy Presents Beer’s Criteria and its implications Guidelines for psychotropic medications in LTC facilities Special considerations for frail older adults Patient Care Pearls, case studies, key points, and chapter summaries

As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

A change is coming. By 2050, the world's 65-and-older population will double, and the 85 and older population will mushroom fivefold. As the number of older adults surge, so too will the number of medication management challenges pharmacists and other health care providers experience. For the geriatric population, complex cases are often the norm, and providing safe and effective care can mean considering assessments of function and cognition, contacting multiple prescribers, and understanding a patient's history, beliefs, and care giving situation before making therapeutic decisions.Fundamentals of Geriatric Pharmacotherapy: An Evidence-Based Approach gives practitioners the information they need to improve outcomes and personalize care for elderly patients. Section 1 explores important foundational concepts such as social and behavioral issues, ethical considerations, biomedical principles of aging, geriatric assessment, and polypharmacy. Section 2 covers common disease states in aging adults, providing evidence-based treatment information as well as helpful tips for minimizing common problems and contending with clinical controversies. Particular attention is given to how treatment can differ along the spectrum of active elderly to frail elderly patients.Useful features throughout the book guide practitioners in navigating the maze of information required when caring for an older patient. These include: Summarized treatment guidelines Reviews of the evidence-base Special focus on recommendations for frail elderly At least one full case study, or more, in each chapter Clinical Pearls Key Points highlight important information in each chapter Key terms and definitions The demands of an aging population mean a greater understanding of geriatric pharmacotherapy will soon be essential for all health care providers. Fundamentals of Geriatric Pharmacotherapy ensures that you'll have the information needed to respond appropriately

Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.

This user-friendly, comprehensive drug reference, point-of-care usage -provides clinical information on more than 1000 drugs and their use in geriatric patients. In addition to dosage information and clinical indications, this reference also addresses the challenging issues of drug-drug and drug-disease interactions, polypharmacy, toxicity, compromised renal and hepatic function, withdrawal events, and more. Useful summary sections provide ‘at a glance' conclusions, recommendations and clinical pearls. Get comprehensive guidance on all the drugs you could conceivably encounter in treating the geriatric patient. Better serve your geriatric patients with dosage and usage guidelines developed specifically for them. Find information quickly using the practical, clinically-focused, full-color format.

Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.