Phytomedicine And Alzheimer S Disorder

Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by a progressive loss of memory. Despite several advances in the field of medical therapeutics, a viable treatment for Alzheimer's disease would be of great importance. Medicinal plants represent a largely untapped reservoir of natural medicines and potential sources of anti-Alzheimer’s drugs. The structural diversity of their phytoconstituents makes these plants a valuable source of novel lead compounds in the quest for drugs to treat Alzheimer's disease. Based on traditional literature and up-to-date research, various new therapeutically active compounds have been identified from phytoextracts, which could be useful in the treatment of cognitive disorders. Phytomedicine and Alzheimer’s Disease presents information on Mechanistic aspects of neurodegeneration in Alzheimer’s disease and the role of phytochemicals as restorative agents Understanding the complex biochemical aspects of Alzheimer’s disease Pre-clinical approaches to evaluating drugs to target Alzheimer’s disease Assessing alternative approaches to treating Alzheimer’s disease and the role of alternative medicine to delay the symptomatic progression of this disease Epigenetic changes in Alzheimer’s disease and possible therapeutic or dietary interventions This book serves as an excellent resource for scientific investigators, academics, biochemists, botanists, and alternative medicine practitioners who work to advance the role of phytomedicines in treating Alzheimer’s disease.

"Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by progressive loss of memory. Despite several advancements in the field of medicinal therapeutics, a viable treatment for Alzheimer's disease is the need of great importance. Medicinal plants represent a great deal of untapped reservoir of natural medicines and potential source of anti-Alzheimer's drug. The structural diversity of their phytoconstituents makes them a valuable source of novel lead compounds for the quest of drugs to treat Alzheimer's disease. Based on the traditional literature, various new therapeutically active compounds have been isolated from phytoextracts useful in cognitive disorders. The book "Phytomedicine and Alzheimer's disorder" presents information on mechanistic aspects of neurodegeneration in Alzheimer's disease and role of phytochemicals as restorative agents, helps in understanding the complex biochemical aspects of Alzheimer's disorder, pre-clinical approaches to evaluate drugs targeting Alzheimer's disease, alternative approach to encounter Alzheimer's disease and role of alternative medicine to delay the symptomatic progression of the same epigenetic alterations in Alzheimer's disease and its therapeutic, dietary interventions This book serves as an excellent resource for scientific investigators, academician, biochemists, botanists, alternative medicine practitioners who are intended to emphasize the role of phytomedicines to treat Alzheimer's disease"--

The eighth volume of Evidence-based Clinical Chinese Medicine aims to provide a multi-faceted 'whole evidence' analysis of the management of Alzheimer's disease in Chinese and integrative medicine.Beginning with overviews of how Alzheimer's disease is conceptualised and managed in both conventional medicine and contemporary Chinese medicine, the authors then provide detailed analyses of how dementia and memory disorders were treated with herbal medicine and acupuncture in past eras.In the subsequent chapters, the authors comprehensively review the current state of the clinical trial evidence for Chinese herbal medicines, acupuncture and other Chinese medicine therapies in the management of Alzheimer's disease, as well as analyse and evaluate the results of these studies from an evidence-based medicine perspective. The outcomes of these analyses are summarised and discussed in terms of their implications for the clinical practice of Chinese medicine and for future research.This book can inform clinicians and students in the fields of integrative and Chinese medicine of the current state of the evidence for a range of Chinese medicine therapies in Alzheimer's disease, including the use of particular herbal formulas and acupuncture treatments in order to assist clinicians in making evidence-based decisions in patient care.

Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by a progressive loss of memory. Despite several advances in the field of medical therapeutics, a viable treatment for Alzheimer's disease would be of great importance. Medicinal plants represent a largely untapped reservoir of natural medicines and potential sources of anti-Alzheimer’s drugs. The structural diversity of their phytoconstituents makes these plants a valuable source of novel lead compounds in the quest for drugs to treat Alzheimer's disease. Based on traditional literature and up-to-date research, various new therapeutically active compounds have been identified from phytoextracts, which could be useful in the treatment of cognitive disorders. Phytomedicine and Alzheimer’s Disease presents information on Mechanistic aspects of neurodegeneration in Alzheimer’s disease and the role of phytochemicals as restorative agents Understanding the complex biochemical aspects of Alzheimer’s disease Pre-clinical approaches to evaluating drugs to target Alzheimer’s disease Assessing alternative approaches to treating Alzheimer’s disease and the role of alternative medicine to delay the symptomatic progression of this disease Epigenetic changes in Alzheimer’s disease and possible therapeutic or dietary interventions This book serves as an excellent resource for scientific investigators, academics, biochemists, botanists, and alternative medicine practitioners who work to advance the role of phytomedicines in treating Alzheimer’s disease.

Naturally Occurring Chemicals against Alzheimer’s Disease offers a detailed discussion on the roles, molecular mechanisms, structural activity relationships, toxicology and clinical data on phytochemicals in relation to Alzheimer’s disease. The book examines the available phytochemicals and plants that are potentially effective, also determining the role and molecular targets of these phytochemicals in combating AD. This comprehensive resource will be helpful to researchers who are working on herbal drugs on AD, phytochemistry, pharmacology, toxicology, clinical trials, neuroscience and advancement in formulations. Provides information on phytochemistry, pharmacology, toxicology, clinical trials, and advancement in formulations specific to Alzheimer’s Disease in a single source Explores natural compounds, which can be more affordable to the majority of Alzheimer’s Disease patients, who will increasingly be in developing countries Covers a wide array of specific chemical compounds

Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders * Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems

"Evidence-based Clinical Chinese Medicine: Vol. 1 Chronic Obstructive Pulmonary Disease provides a "whole evidence" analysis of the Chinese medicine management of chronic obstructive pulmonary disease (COPD). Evidence from the classical Chinese medicine literature, contemporary clinical literature, and the outcomes of clinical trials and experimental studies are reviewed, analysed and synthesised. The data from all these sources are condensed to provide evidence-based statements which will inform clinical practice and guide future research. This book has been designed to be an easy reference at the point of care. During a patient consultation, Chinese medicine practitioners can refer to this book for guidance on which Chinese herbal medicine formulas, specific herbs, or acupuncture points, can best treat their patient, and be confident there is evidence which supports its use. Currently, Chinese medicine practitioners who develop a special interest in a particular health condition such as COPD have to consult a variety of sources to further their knowledge. Typically, they use the contemporary clinical literature to understand the theory, aetiology, pathogenesis and obtain expert opinions on the Chinese medicine management of COPD. They search the electronic literature to identify systematic reviews of clinical trials, if any exists, to obtain assessments of the current state of the clinical evidence for particular interventions. If they have the skills and resources, they may search the classical Chinese medicine literature for an historical perspective on treatments that have stood the test of time. This book provides all of this information for practitioners in one handy, easy to use reference. This allows practitioners to focus on their job of providing high quality healthcare, with the knowledge it is based on the best available evidence"--Publisher's website.

Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.