Prebiotic Chemistry And Life S Origin

This book provides a broad but in-depth analysis of the latest discoveries in prebiotic chemistry from the microscopic to the macroscopic scale.

Studying the origin of life is one of man’s greatest achievements over the last sixty years. The fields of interest encompassed by this quest are multiple and interdisciplinary: chemistry, physics, biology, biochemistry, mathematics, geology but also statistics, atmospheric science, meteorology, oceanography, and astrophysics. Recent scientific discoveries, such as water on Mars and the existence of super-Earths with atmospheres similar to primordial Earth, have pushed researchers to simulate prebiotic conditions in explaining the abiotic formation of molecules essential to life. This collection of articles offers an overview of recent discoveries in the field of prebiotic chemistry of biomolecules, their formation and selection, and the evolution of complex chemical systems.

This book presents an overview of current views on the origin of life and its earliest evolution. Each chapter describes key processes, environments and transition on the long road from geochemistry and astrochemistry to biochemistry and finally to the ancestors of today ́s organisms. This book combines the bottom-up and the top-down approaches to life including the origin of key chemical and structural features of living cells and the nature of abiotic factors that shaped these features in primordial environments. The book provides an overview of the topic as well as its state of the art for graduate students and newcomers to the field. It also serves as a reference for researchers in origins of life on Earth and beyond.

Born from twenty-five years of experimental research and a decade of bibliographic studies, this publication delves into the fascinating theory of life's abiotic origins. It begins with simple amino acids, the building blocks of proteins, revealing how these compounds, present from the prebiotic era and discovered in ancient meteorites, may have been pivotal in life's evolutionary journey. Focusing particularly on amino acids' chirality—that is, their existence in mirror-image right and left forms—the author probes the critical enigma of their separation and why the left (L) form dominates in all known living beings. The book sparks a compelling discussion about how this bifurcation might have occurred at life's very inception and the ultimate fate of the right form. The text further extends its reach, proposing theories on the genetic code's origins, the selection of the 20 natural amino acids from many known, and a physical theory of consciousness in bacteria. "Prebiotic Chemistry and the Origin of Life" is more than a trek through the complexities of chemistry and molecular biology; it's an enthralling journey into some of life's most profound existential questions.

The origin of life is one of the biggest unsolved scientific questions. This book deals with the formation and first steps of the chemical evolution of nucleic acids, including the chemical roots behind the origin of their components from the simplest sources in a geochemical context. Chemical evolution encompasses the chemical processes and interactions conducive to self-assembly and supramolecular organization, leading to an increase of complexity and the emergence of life. The book starts with a personal account of the pioneering work of Stanley Miller and Jeffrey Bada on the Chemistry of Origins of Life and how the development of organic chemistry beginning in the 19th century led to the emergence of the field of prebiotic chemistry, situated at the frontier between organic, geo- and biochemistry. It then continues reviewing in tutorial manner current central topics regarding the organization of nucleic acids: the origin of nucleobases and nucleosides, their phosphorylation and polymerization and ultimately, their self-assembly and supramolecular organization at the inception of life.

What is life? How, where, and when did life arise? These questions have remained most fascinating over the last hundred years. Systems chemistry is the way to go to better understand this problem and to try and answer the unsolved question regarding the origin of Life. Self-organization, thanks to the role of lipid boundaries, made possible the rise of protocells. The role of these boundaries is to separate and co-locate micro-environments, and make them spatially distinct; to protect and keep them at defined concentrations; and to enable a multitude of often competing and interfering biochemical reactions to occur simultaneously. The aim of this Special Issue is to summarize the latest discoveries in the field of the prebiotic chemistry of biomolecules, self-organization, protocells and the origin of life. In recent years, thousands of excellent reviews and articles have appeared in the literature and some breakthroughs have already been achieved. However, a great deal of work remains to be carried out. Beyond the borders of the traditional domains of scientific activity, the multidisciplinary character of the present Special Issue leaves space for anyone to creatively contribute to any aspect of these and related relevant topics. We hope that the presented works will be stimulating for a new generation of scientists that are taking their first steps in this fascinating field.

This volume contains the lectures presented at the second course of the International School of Space Chemistry held in Erice (Sicily) from October 20 - 30 1991 at the "E. Majorana Centre for Scientific Culture". The course was attended by 58 participants from 13 countries. The Chemistry of Life's Origins is well recognized as one of the most critical subjects of modem chemistry. Much progress has been made since the amazingly perceptive contributions by Oparin some 70 years ago when he first outlined a possible series of steps starting from simple molecules to basic building blocks and ultimate assembly into simple organisms capable of replicating, catalysis and evolution to higher organisms. The pioneering experiments of Stanley Miller demonstrated already forty years ago how easy it could have been to form the amino acids which are critical to living organisms. However we have since learned and are still learning a great deal more about the primitive conditions on earth which has led us to a rethinking of where and how the condition for prebiotic chemical processes occurred. We have also learned a great deal more about the molecular basis for life. For instance, the existence of DNA was just discovered forty years ago.