Principles And Practice Of Fertility Preservation

The specialty of fertility preservation offers patients with cancer, who are rendered infertile by chemo- and radiotherapy, the opportunity to realize their reproductive potential. This gold-standard publication defines the specialty. The full range of techniques and scientific concepts is covered in detail, and the author team includes many of the world's leading experts in the field. The book opens with introductions to fertility preservation in both cancer and non-cancer patients, followed by cancer biology, epidemiology and treatment, and reproductive biology and cryobiology. Subsequent sections cover fertility preservation strategies in males and females, including medical/surgical procedures, ART, cryopreservation and transplantation of both ovarian tissue and the whole ovary, and in-vitro follicle growth and maturation. Concluding chapters address future technologies, as well as ethical, legal and religious issues. Richly illustrated throughout, this is a key resource for all clinicians specializing in reproductive medicine, gynecology, oncology, hematology, endocrinology and infertility.

A synthesis of the most up-to-date research and technologies in fertility preservation, written by leading experts in the field.

This comprehensive textbook on fertility preservation is a gold-standard publication covering all scientific and clinical subjects related to this field.

This comprehensive, multidisciplinary guide provides an up-to-date presentation of fertility preservation techniques with male cancer patients and other challenging conditions. Divided into four thematic sections, part one provides an overview of the pathophysiologic processes interrelating cancer and its treatment with infertility and discusses different methods of sperm preservation and fertility outcomes in cancer patients. Part two then explores male fertility preservation in various non-cancerous conditions, such as immunosuppressed, hypogonadal and transgender patients. The fundamental principles of cryobiology and sperm optimization are covered in part three, which also offers essential building blocks for scientists to develop a sperm banking service and implement high standards of practice. The final section describes the current practices of male fertility preservation along with its psychological impact on patients, and extends beyond to future innovative methods—tissue preservation, xenografting and artificial gametes—being researched and implemented in this field. Fertility preservation among cancer patients and survivors is an evolving practice, which involves focused research and timely collaboration of professionals from related fields. The Complete Guide to Male Fertility Preservation is unique and original in its design and will appeal to a larger audience of andrologists, reproductive endocrinologists, urologists, embryologists, and all other clinicians practicing reproductive medicine and oncology.

VOLUME 1: INFERTILITY SECTION 1: ANATOMY AND PHYSIOLOGY 1. Anatomy of the Reproductive System 2. Regulation and Physiology of Menstrual Cycle 3. Oogenesis and Folliculogenesis 4. Spermatogenesis 5. Fertilization and Embryogenesis 6. Implantation 7. Embryo Endometrial Crosstalk and Endometrial Receptivity SECTION 2: REPRODUCTIVE ENDOCRINOLOGY 8. Synthesis and Metabolism of Steroid Hormones 9. Puberty and Aberrations 10. Amenorrhea 11. Endocrine Disorders Affecting Reproduction 12. Hirsutism 13. Luteal Phase Defect 14. Anovulation 15. Declining Fertility SECTION 3: COMBINED TOPICS 16. Evaluation of Infertility 17. Immunology and Infertility 18. Cytogenetics and Subfertility 19. Obesity and Infertility 20. Unexplained Infertility 21. Fertility Preservation 22. Counseling in Infertility 23. Assisted Reproductive Technology in Patients with Chronic Medical Disorders SECTION 4: MALE INFERTILITY 24. Etiopathogenesis of Male Infertility 25. Clinical and Endocrinological Evaluation of Infertile Male 26. Sexual Dysfunction in Male Infertility 27. Ultrasound in Male Infertility 28. Medical Management of Male Infertility 29. Azoospermia: Evaluation and Management 30. Varicocele and Infertility 31. Spinal Cord Injuries and Male Infertility 32. Algorithms for Genetic Evaluation of Infertile Males SECTION 5: FEMALE FACTOR INFERTILITY 33. Uterine Factors in Infertility 34. Tubal Factors in Infertility 35. Infections and Infertility 36. Tuberculosis and Infertility 37. Sonoendocrinology and Cycle Monitoring Assisted Reproduction Technology 38. Transvaginal Ultrasound and Doppler in Infertility 39. Polycystic Ovary Syndrome 40. Assessment of Ovarian Reserve 41. Endometriosis 42. Endoscopy in Infertility 43. Reconstructive Surgeries Enhancing Fertility SECTION 6: INTRAUTERINE INSEMINATION 44. Intrauterine Insemination 45. Optimizing Success in Intrauterine Insemination SECTION 7: OVARIAN STIMULATION 46. Drugs for Ovarian Stimulation 47. Ovulation Induction and Ovarian Stimulation Protocols 48. Role of Adjuvants in Ovarian Stimulation 49. Gonadotropinreleasing Hormone Analogs 50. Monitoring of Ovarian Stimulation 51. Ovulation Trigger 52. Individualized Controlled Ovarian Stimulation 53. In Vitro Fertilization Lite 54. Role of Luteinizing Hormone in Ovarian Stimulation 55. Anesthesia in Assisted Reproductive Techniques 56. Oocyte Retrieval. 57. Embryo Transfer 58. Troubleshooting in Assisted Reproductive Technology 59. Luteal Phase Support SECTION 8: DILEMMA IN ART 60. Poor Responder 61. Recurrent Implantation Failure 62. Empty Follicle Syndrome 63. Role of Aneuploidy Screening in Preimplantation Embryos 64. Preimplantation Genetic Testing of Embryos 65. Epigenetics and Assisted Reproductive Technology SECTION 9: COMPLICATIONS IN ART 66. Ovarian Hyperstimulation Syndrome 67. Ectopic Pregnancy 68. Multipleorder Births SECTION 10: THIRD PARTY REPRODUCTION 69. Oocyte and Sperm Donation 70. Surrogacy in Assisted Reproductive Technology 71. Assisted Reproductive Technology Guidelines 72. Adoption 73. LGBTQ and Fertility 74. Transgender Population and Fertility SECTION 11: OUTCOME FOLLOWING ASSISTED REPRODUCTIVE TECHNIQUE 75. Maternal and Fetal Outcomes Following Assisted Reproductive Technique 76. Early Pregnancy Scan 77. Recurrent Pregnancy Loss: From Diagnostic Dilemmas to Clinical Decisions SECTION 12: RECENT ADVANCES 78. Bioengineered Human Endometrium In Vitro. 79. Recent Trends in A...

Ovarian Freezing and Transplantation provides methods and techniques of ovarian tissue harvesting and cryopreservation, including instructional videos. This book will benefit a wide audience, guiding infertility specialists, fellows, residents, reproductive surgeons, reproductive endocrinologists, pediatric surgeons, embryologists, infertility nurses and gynecologists as they work together. Ovarian cryopreservation and transplantation is rapidly gaining acceptance as a successful and established fertility preservation strategy in cancer patients and beyond. Unlike other fertility preservation strategies, it can be performed in children as well as adults and restores natural ovarian function and fertility, hence this is a welcomed resource on the topic. Provides instructional videos, materials and an equipment list for ovarian tissue harvesting and cryopreservation, along with protocols for ovarian tissue cryopreservation thawing and transplantation Presents instructional video coverage of ovarian tissue cryopreservation for use at fertility centers around the globe Fulfills a specific niche in the literature, providing a comprehensive reference on ovarian tissue freezing and transplantation Includes a foreword written by a cancer survivor who successfully received this procedure

Help your patients through the maze of infertility treatments Infertility is suffered by around 1 in 7 couples and can be a source of confusion for both partners, providing high stress on relationships. 25% of cases are explained through male infertility, 50% through female infertility, whilst 25% are generally unexplained. The possible causes and solutions are many and complex. Infertility, one of the first in the new Gynecology in Practice series, assists gynecologists and family practitioners to better care for their patients who have trouble conceiving. The authors provide a strong focus on effective diagnosis and management. Following a review of the factors that affect fertility, Infertility takes a practical approach to: Evaluation of fertility Management and treatment Complications Pre-implantation screening Fertility preservation Gynecology in Practice The Gynecology in Practice series provides clinical 'in the office' or 'at the bedside' guides to effective patient care for gynecologists. The tone is practical, not academic, with authors offering guidance on what might be done and what should be avoided. The books are informed by evidence-based practice and feature: Algorithms and guidelines where they are appropriate ''Tips and Tricks' boxes – hints on improving outcomes 'Caution' warning boxes – hints on avoiding complications 'Science Revisited' – quick reminder of the basic science principles Summaries of key evidence and suggestions for further reading

This practical book focuses on the most recent advances in fertility preservation in oncological and non-oncological patients. It presents the steps that need to be followed prior to treatment for successful fertility preservation, and describes in detail the medical conditions requiring fertility preservation, including precise information on the risk of fertility loss, prognosis, risk of ovarian metastasis and other possible risks. The book also provides information on how to perform the preservation techniques (success rates, risks, etc.) and on what to do after the treatment (in cases of bleeding during chemotherapy, menopause, wish to conceive, etc.). Written by experts in the field, including members of the globally known network FertiPROTEKT and leading oncologists and specialists, this practical and easy-to-use book is a valuable resource for all clinicians involved in fertility preservation for patients with specific diseases