Principles And Practice Of Pediatric Endocrinology

This first edition of Principles and Practice of Pediatric Endocrinology brings together 30 authors from 4 countries to present an update on the molecular basis of endocrine disorders in infants, children and adolescents as well as the diagnosis and treatment of these conditions. It is intended for the use of practitioners, fellows and clinical and “bench-top” researchers in this field, and presents advances in each of 12 areas of the normal and abnormal endocrine state. The work is a tribute to all those past and present whose research and clinical efforts resulted in the rapidly increasing accumulation of knowledge in this field, and includes comprehensive, practical clinical presentations in the form of an Atlas following each chapter after the comprehensive introductory chapter by Drs. Root and Rogol. This publication owes a great debt to Lawson Wilkins, a Baltimore pediatrician who first formally established the separate discipline of pediatric endocrinology, to Edwards Park, Fuller Albright, Bob Blizzard, Claude Migeon, Harold and Helen Harrison, James Tanner and to so many others: giants upon whose shoulders pediatric endocrinologists stand. Disorders of growth and pubertal development are the cornerstones of pediatrics as they are present in many children with chronic illness as well as in children whose growth and pubertal development are influenced by genetics and family history. These may have identifiable causes in pituitary, thyroid, adrenal or gonadal function, and examples are well represented in this book. Obesity and diabetes (types I and 2) are, likewise, diseases of childhood that are becoming increasingly and significantly prevalent and are included in this work. Disorders of calcium/phosphorus (especially the often forgotten but not gone Vitamin D deficiency rickets) and water metabolism are presented, and errors of sexual differentiation (an increasingly controversial issue) are highlighted. It is the hope of the editors that this work will assist the practitioner and researcher in this field in his or her efforts to diagnose, treat and establish the etiology of endocrine disorders in infants, children and adolescents.

Market: pediatricians, pediatric residents, pediatric nurse practitioners, endocrinologists 500 full-color illustrations Full-color presentation includes features such as a consistent outline format, icons throughout, boxed elements, “tips” and “pearls” with graphics to draw the reader's eye

The go-to guide for managing endocrine problems in children – completely updated for today’s practice Part of the Pediatric Practice series, Pediatric Practice: Endocrinology is an outstanding clinical analysis and decision-making tool for those treating endocrine problems in children. Featuring an innovative problem-oriented approach, this well-illustrated, full-color guide skillfully integrates pathophysiology with clinical management. Numerous figures illustrate the principles of normal and abnormal physiology and treatment rationale and effects. Since an understanding of the clinical manifestations and treatments of endocrine disorders begins with knowledge of concepts of hormone action and principles of feedback control, the first chapter, "General Concepts and Physiology," links genetics, cell biology, and physiology with pathophysiology to provide a clear and approachable overview of endocrine systems. Subsequent chapters discuss disorders of growth, puberty, thyroid and adrenal glands, sex development, calcium and bone metabolism, water homeostasis, and carbohydrate metabolism and its comorbidities. In this second edition, contributing authors have updated all chapters. Important additions include sections on genetics for the endocrinologist in the general concepts chapter, an overview of the physiology and treatment of metabolic syndrome and dyslipidemia in the obesity chapter, and the addition of a new chapter on enteric hormones. Features of the Pediatric Practice Series The Pediatric Practice series simplifies the care of pediatric patients by delivering: Tips that tell you what you must know--and what you must do--at every stage of care Diagnostic and treatment algorithms Signs/Symptoms and Differential Diagnosis boxes When to Refer boxes, which examine all the relevant clinical considerations Diagnostic Tests--with a realistic emphasis on the right tests to order Medical Treatment coverage that includes drugs, dosages, and administration in an easy-to-read tabular format Convenient icons and a consistent chapter design Numerous clinical color photos and didactic diagrams

Introduction to clinical pediatrics. 1. Growth and development - anticipatory guidance / Arthur N. Feinberg. 2. Immunizations / Arthur N. Feinberg and Victoria Langston. 3. Genetic counseling / Trudy McKanna and Helga V. Toriello. 4. Dental problems in the general pediatric office / Joseph D'Ambrosio. 5. Ear, nose, and throat problems in general pediatrics / Vinay N. Reddy. 6. Sleep disorders in children and adolescents / Bantu Samridhi Chhangani. 7. Adolescent health / Donald E. Greydanus and Dilip R. Patel. 8. The internet and the pediatrician in the 21st century / Vinay N. Reddy -- Mental health. 9. Common topics in pediatric psychiatry / Joseph L. Calles, Jr. 10. Psychotic symptoms in children and adolescents / Ahsan Nazeer -- Common medical disorders. 11. Clinical issues in endocrinology / Manmohan K. Kamboj. 12. Cardiology / Thomas A. Melgar and Richard A. Humes. 13. Pulmonology / John H. Marks. 14. Gastroenterology / Lisa A. Feinberg and Orhan K. Atay. 15. Concepts of neurology in pediatrics / Donald E. Greydanus [und weitere]. 16. Pediatric hematology and oncology / Renuka Gera [und weitere]. 17. Pediatric dermatology / J. Donald Hare. 18. Concepts of infectious diseases / H. Dele Davies and Stephen K. Obaro -- Concepts of genitourinary disorders. 19. Treatment of pediatric hypertension / Alfonso D. Torres. 20. Nephrology / Timothy E. Bunchman and Vimal Master Sankar Raj. 21. Concepts of enuresis / Tracy Pierce. 22. Selected topics in pediatric urology / Julian H. Wan -- Concepts of pediatric gynecology and sexual abuse. 23. Office gynecologic problems in prepupertal girls / Hatim A. Omar, Amit Deokar and Wendy Jackson. 24. Medical evaluation of child sexual abuse / Colette A. Gushurst and Vincent J. Palusci -- Concepts of the musculoskeletal system. 25. Concepts of rheumatology / Dilip R. Patel and Mary D. Moore. 26. Concepts of sports medicine / Dilip R. Patel. 27. Physiological deformities of the lower extremity in children / Avinash L. Jadhav and Dale E. Rowe

The go-to guide for managing endocrine problems in children – completely updated for today’s practice Part of the Pediatric Practice series, Pediatric Practice: Endocrinology is an outstanding clinical analysis and decision-making tool for those treating endocrine problems in children. Featuring an innovative problem-oriented approach, this well-illustrated, full-color guide skillfully integrates pathophysiology with clinical management. Numerous figures illustrate the principles of normal and abnormal physiology and treatment rationale and effects. Since an understanding of the clinical manifestations and treatments of endocrine disorders begins with knowledge of concepts of hormone action and principles of feedback control, the first chapter, "General Concepts and Physiology," links genetics, cell biology, and physiology with pathophysiology to provide a clear and approachable overview of endocrine systems. Subsequent chapters discuss disorders of growth, puberty, thyroid and adrenal glands, sex development, calcium and bone metabolism, water homeostasis, and carbohydrate metabolism and its comorbidities. In this second edition, contributing authors have updated all chapters. Important additions include sections on genetics for the endocrinologist in the general concepts chapter, an overview of the physiology and treatment of metabolic syndrome and dyslipidemia in the obesity chapter, and the addition of a new chapter on enteric hormones. Features of the Pediatric Practice Series The Pediatric Practice series simplifies the care of pediatric patients by delivering: Tips that tell you what you must know--and what you must do--at every stage of care Diagnostic and treatment algorithms Signs/Symptoms and Differential Diagnosis boxes When to Refer boxes, which examine all the relevant clinical considerations Diagnostic Tests--with a realistic emphasis on the right tests to order Medical Treatment coverage that includes drugs, dosages, and administration in an easy-to-read tabular format Convenient icons and a consistent chapter design Numerous clinical color photos and didactic diagrams

This New Edition is today's most comprehensive, definitive reference in the field, incorporating all of today's explosive discoveries in basic and clinical endocrinology. Its reliable, cutting-edge guidance for a full range of problems is combined with a wealth of information on the physiological, biochemical, and genetic basis at the molecular biological level. Dr. Mark A. Sperling and 33 contributing experts bring readers the benefits of discovery at the bench and its application at the bedside. New chapters, extensive revisions, and compelling updates will keep readers at the forefront of the diagnosis and management of endocrine disease in children. Incorporates the explosive growth in molecular biology as it relates to developmental and pediatric endocrinology. Extensively revised and updated chapters throughout reflect the latest information. Coverage of up-to-the-minute topics in the field, including molecular, biochemical, and clinical basis of hyperinsulinemic hypoglycemia of infancy and childhood diabetes mellitus energy balance/obesity growth hormone paradigms of mechanisms of hormone action, and others Contributions from new authors from distinguished institutions Numerous brand-new illustrations depict the most current information, particularly the basic science/genetic basis of certain entities

An up-to-date and concise guide to the clinical management of pediatric endocrine disorders. The text covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages.

Practical Pediatric Endocrinology in a Limited Resource Setting provides a guide for managing pediatric endocrine problems in a limited resource setting, together with an outline of the bases for these disorders. The book outlines a plan for coming to a likely diagnosis in situations where resources are constrained, and suggests ways to access more sophisticated technologies for diagnostic confirmation and extension of available tools. Further extending and complementing each chapter is a series of scenarios for use as teaching and learning tools. Together with a clinical question, all chapters include a suggested outline for assessment that assists readers facing similar situations in daily practice. Each scenario works through a typical series of deductive steps used to establish a working diagnosis, while considering both a differential diagnosis and reminding readers of current knowledge around the subject matter. Provides a working knowledge of pediatric endocrinology, from the viewpoint of practical application, for residents and clinicians practicing in settings with scarce material resources Features clinically based chapters, empahsising workable diagnoses and management plans in limited resource situations Includes information on Type 1 diabetes mellitus, given its increasing prevalence worldwide Describes basic research techniques and planning, intended to foster collaboration between colleagues and other centers in clinical or basic research, which can inform clinical practice and drive innovation