Principles Of Biological Autonomy

Since Darwin, Biology has been framed on the idea of evolution by natural selection, which has profoundly influenced the scientific and philosophical comprehension of biological phenomena and of our place in Nature. This book argues that contemporary biology should progress towards and revolve around an even more fundamental idea, that of autonomy. Biological autonomy describes living organisms as organised systems, which are able to self-produce and self-maintain as integrated entities, to establish their own goals and norms, and to promote the conditions of their existence through their interactions with the environment. Topics covered in this book include organisation and biological emergence, organisms, agency, levels of autonomy, cognition, and a look at the historical dimension of autonomy. The current development of scientific investigations on autonomous organisation calls for a theoretical and philosophical analysis. This can contribute to the elaboration of an original understanding of life - including human life - on Earth, opening new perspectives and enabling fecund interactions with other existing theories and approaches. This book takes up the challenge.

This volume describes features of autonomy and integrates them into the recent discussion of factors in evolution. In recent years ideas about major transitions in evolution are undergoing a revolutionary change. They include questions about the origin of evolutionary innovation, their genetic and epigenetic background, the role of the phenotype and of changes in ontogenetic pathways. In the present book, it is argued that it is likewise necessary to question the properties of these innovations and what was qualitatively generated during the macroevolutionary transitions. The author states that a recurring central aspect of macroevolutionary innovations is an increase in individual organismal autonomy whereby it is emancipated from the environment with changes in its capacity for flexibility, self-regulation and self-control of behavior. The first chapters define the concept of autonomy and examine its history and its epistemological context. Later chapters demonstrate how changes in autonomy took place during the major evolutionary transitions and investigate the generation of organs and physiological systems. They synthesize material from various disciplines including zoology, comparative physiology, morphology, molecular biology, neurobiology and ethology. It is argued that the concept is also relevant for understanding the relation of the biological evolution of man to his cultural abilities. Finally the relation of autonomy to adaptation, niche construction, phenotypic plasticity and other factors and patterns in evolution is discussed. The text has a clear perspective from the context of systems biology, arguing that the generation of biological autonomy must be interpreted within an integrative systems approach.

This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems. Chapters focus on defining and explaining the regulatory molecular mechanisms behind different aspects of autonomy and self-organization in the sense of autonomous coding, data processing, structure (mass) formation and energy production in a biological system. Subsequent chapters discuss the cross-talk among mechanisms of energy, and mass and information, transformation in biological systems. Other chapters focus on applications regarding therapeutic approaches in regenerative medicine. Molecular Mechanisms of Autonomy in Biological Systems is an indispensable resource for scientists and researchers in regenerative medicine, stem cell biology, molecular biology, tissue engineering, developmental biology, biochemistry, biophysics, bioinformatics, as well as big data sciences, complexity and soft computing.

The term ‘systems theory’ is used to characterize a set of disparate yet related approaches to fields as varied as information theory, cybernetics, biology, sociology, history, literature, and philosophy. What unites each of these traditions of systems theory is a shared focus on general features of systems and their fundamental importance for diverse areas of life. Yet there are considerable differences among these traditions, and each tradition has developed its own methodologies, journals, and forms of anaylsis. This book explores this terrain and provides an overview of and guide to the traditions of systems theory in their considerable variety. The book draws attention to the traditions of systems theory in their historical development, especially as related to the humanities and social sciences, and shows how from these traditions various contemporary developments have ensued. It provides a guide for strains of thought that are key to understanding 20th century intellectual life in many areas.

This book constitutes the refereed proceedings of the 9th European Conference on Artificial Life, ECAL 2007, held in Lisbon, Portugal. The 125 revised full papers cover morphogenesis and development, robotics and autonomous agents, evolutionary computation and theory, cellular automata, models of biological systems and their applications, ant colony and swarm systems, evolution of communication, simulation of social interactions, self-replication, artificial chemistry.

Self-organization of systems belonging to quite different discipl ines has been a central topic of synergetics since its beginning. I am therefore particularly plea sed that Hans Ulrich and Gilbert Probst have not only undertaken to organize an interdisciplinary meeting on Self-Organization and Management of Social Systems, but have also edited these articles written by leading scientists after and based upon that symposium. While the previous volumes of the Springer Series in Synergetics were mainly de voted to physical, chemical and biological systems, with only the book by W. Weidlich and G. Haag deal i ng with "Quant i tat i ve Soc i 01 ogy" (Spri nger Ser. Syn., Vo 1. 14), the present volume opens a new perspective. As the reader will notice, the multitude of facets of self-organization is well reflected by various authors belonging to different discipl ines and representing different schools of thought. When such a wide scope of fields - ranging from phy sics to sociology - is covered, it is not surprising that the existence of a "hiatus" between sociology and the natural sciences was felt by some participants.

Emerging in the 1940s, the first cybernetics—the study of communication and control systems—was mainstreamed under the names artificial intelligence and computer science and taken up by the social sciences, the humanities, and the creative arts. In Emergence and Embodiment, Bruce Clarke and Mark B. N. Hansen focus on cybernetic developments that stem from the second-order turn in the 1970s, when the cyberneticist Heinz von Foerster catalyzed new thinking about the cognitive implications of self-referential systems. The crucial shift he inspired was from first-order cybernetics’ attention to homeostasis as a mode of autonomous self-regulation in mechanical and informatic systems, to second-order concepts of self-organization and autopoiesis in embodied and metabiotic systems. The collection opens with an interview with von Foerster and then traces the lines of neocybernetic thought that have followed from his work. In response to the apparent dissolution of boundaries at work in the contemporary technosciences of emergence, neocybernetics observes that cognitive systems are operationally bounded, semi-autonomous entities coupled with their environments and other systems. Second-order systems theory stresses the recursive complexities of observation, mediation, and communication. Focused on the neocybernetic contributions of von Foerster, Francisco Varela, and Niklas Luhmann, this collection advances theoretical debates about the cultural, philosophical, and literary uses of their ideas. In addition to the interview with von Foerster, Emergence and Embodiment includes essays by Varela and Luhmann. It engages with Humberto Maturana’s and Varela’s creation of the concept of autopoiesis, Varela’s later work on neurophenomenology, and Luhmann’s adaptations of autopoiesis to social systems theory. Taken together, these essays illuminate the shared commitments uniting the broader discourse of neocybernetics. Contributors. Linda Brigham, Bruce Clarke, Mark B. N. Hansen, Edgar Landgraf, Ira Livingston, Niklas Luhmann, Hans-Georg Moeller, John Protevi, Michael Schiltz, Evan Thompson, Francisco J. Varela, Cary Wolfe