Principles Of Radiopharmacolgy

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint.

This comprehensive survey of neuropsychopharmacology is unique in its breadth of coverage, from molecular to behavioural pharmacology, and from basic animal studies of drug action to clinical applications. Lavish illustrations and concise chapter summaries reinforce key concepts, while extensive references point the way to further study. The book is intended for advanced undergraduate, graduate and medical students, and neuroscientists seeking current information on psychoactive drugs.

Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty

* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine

University of North Carolina, Chapel Hill. Revised reprint of the comprehensive reference on pharmacology principles, fundamental concepts, mechanisms of action, and clinical applications of drugs. For students, residents, and practitioners in medicine or pharmacy. 159 contributor, 84 U.S.

With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book

Principles and Practice of Neuropsychopharmacology: A Clinical Reference for Residents, Physicians, and Biomedical Scientists is a concise yet comprehensive book that discusses the drugs used in the treatment of neurological and psychiatric diseases from the perspective of practicing clinicians. There is a considerable overlap between these two specialties as neurologists often use the medicines used by psychiatrists and vice versa. This book addresses the merger of topics of mutual interest for them in a single volume of contemporary pharmacology. It provides detailed coverage of pharmacotherapy of neurological and psychiatric disorders in general practice. The content has been made more accessible with the judicious use of tables and figures, case examples, and details of neurochemical alterations. The book is useful for both beginners and advanced readers as it details clinical practices followed in dealing with psychiatric patients in developing nations like India to enhance practice-oriented learning and provides evidence-based guidelines from world's leading medical bodies. Key Features: Lucid description of pharmacokinetic principles and pharmacodynamics of neuropharmacological agents Thoroughly covers currently used medications in treating a spectrum of diseases of the brain and nervous system Separate chapters dedicated for drugs used for treating depression, mania, anxiety, and insomnia

It is difficult to imagine an era in which there were no selective drugs for treating anxiety, depression, schizophrenia, and other mental ailments. Yet in a remarkably short time these drugs have come to occupy a position of prominence in medical practice throughout the world, and they now account for a major portion of all prescriptions. Most psychotropic drugs were discovered with little premeditation on the part of the inves~ tigator. The drugs simply "worked," often with little rationale, and psychopharmacology has been for many years an empirical discipline in search of scientific underpinnings. In the past decade, a basic science of psychopharmacology has de veloped and grown rapidly. Though psychotropic drugs are exceedingly "young" as drugs in medical practice go, we probably know more about their various mechanisms of action than we know about most drugs in clinical use. Advances in understanding effects of psychopharmaceuticals on the brain have been so prodigious that a new research paradigm has evolved. Instead of being concerned solely with understanding how the drugs act, many researchers now employ psychotropic drugs as tools-often the most powerful ones-to elucidate brain function. Consequently, psychophar macology is central to neurobiology, which in turn has emerged as an important discipline, heir to the preeminent glamor of molecular biology.