Principles Practice Of Neuro Oncology

Neuro-oncologic (brain and spine) cancers account for 19,000 new cases and 13,000 deaths per year. The early and proper diagnosis of these virulent cancers is critical to patient outcomes and diagnosis and treatment strategies are continually evolving. The multidisciplinary team that manages these patients involves medical and radiation oncology, neurosurgery, neuroimaging, nurses and therapists. Principles and Practices of Neuro-Oncology establishes a new gold standard in care through a comprehensive, multidisciplinary text covering all aspects of neuro-oncology. Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive care, imaging, neuroanatomy and neurosurgery, medical oncology and targeted therapies, and radiation oncology for adult and pediatric cancers. Expert contributors from multiple disciplines provide detailed and in-depth discussions of the entire field of neuro-oncology including histopathologic harmonization, neurosurgical techniques, quality of life and cognitive functions, and therapeutic changes in terms of combined modality treatments, advanced radiation techniques, the advent of new drugs, especially targeted agents, and the tantalizing early promise of personalized therapeutic approaches. With contributions from over 180 authors, numerous diagrams, illustrations and tables, and a 48 page color section, Principles and Practice of Neuro-Oncology reflects the breadth and depth of this multi-faceted specialty.

Many recent developments in neuro-oncology relevant to clinical practice have contributed to improved patient care. The most im portant impact of these developments on treatment may have been a change in the attitudes of the neuro-oncologists involved in making decisions regarding patients with gliomas. From an era of uncertainty which led to therapeutic nihilism, we have entered one of active interventions based on objective parameters for the treat ment of gliomas, which may be either slow-growing or rapid kil lers. The histopathological characteristics of gliomatous lesions are intriguing, and it is only recently that a clearer picture has begun to emerge. A group of dedicated neuropathologists has been at tempting to reach a consensus on pathological classification and grading, providing an important landmark in the field of neuro oncology. This book does not mean to provide exhaustive details on the histopathology of gliomas, but rather highlights the main problems in an authoritative chapter. This chapter attempts to guide the reader to a better understanding of all aspects of the neuropathology of glioma. Neuroradiology has recently seen several breakthroughs. Im ages unimaginable a decade ago are now providing us with an al most three-dimensional impression. But the concomitant illusions and artifacts must also be kept in mind, and pragmatic ideas are carefully put forward in this book about the developing body of knowledge concerning the newer imaging techniques.

This book provides a comprehensive overview of the management of brain and skull base tumors. It features detailed insight into the intrinsic molecular biology, anatomical foundation, radiological planning, surgical execution, and the novel therapeutics that guide today’s treatment regimens. The first section features concepts related to the epidemiology and pathological basis of disease processes, including relevant cellular and molecular biology. In the second section, integral anatomical foundations and principles are covered including microsurgical anatomy of the cerebrum, white matter tracts, ventricles, brainstem, skull base, advancements in radiological imaging, and cognitive examinations. Surgical approaches and how to execute these procedures are then subsequently discussed in the third part of the work. Principles of Neuro-Oncology: Brain & Skull Base is a practically applicable guide to the latest treatment techniques available to treat these patients. Therefore, it is an indispensable resource for all physicians who utilize these methodologies in their day-to-day practice.

Provides comprehensive coverage of diagnosis and treatment of all and metastic tumors of the nervous system. Offering streamlined access to sophisticated imaging studies that aid in diagnosis, and to management guidelines for treatment, the text assists those physicians who care for the growing numnbers of patients with nervous system malignancies.

The aim of the Neurology in Practice series is to provide a clinical 'in the office' or 'at the bedside' guide to effective patient care for neurologists in practice and in training. The tone will be practical, not academic. The working assumption is that readers want to know what (and what not) might or should be done, without over emphasis on the why. That said, it is important to review the crucial basic science necessary for effective diagnosis and management, and to provide reminders in the context of the practical chapters. The books will not be heavily referenced, in line with a more practical approach. This allows for smoother reading (and also relieves the burden of comprehensive citing from authors). Key evidence (clinical trials, Cochrane or other meta analyses) should be summarized in 'Evidence at a Glance' boxes and key references such as reviews, major papers can be provided in the 'selected bibliography' at the end of each chapter. Practical guidance will be provided through: the use of algorithms and guidelines where they are appropriate 'Tips and Tricks' boxes – hints on improving outcomes perhaps via practical technique, patient questioning etc 'Caution' warning boxes – hints on avoiding problems, perhaps via contraindications 'Science Revisited' – quick reminder of the basic science principles necessary for understanding

This new resource presents today's most comprehensive, multidisciplinary coverage of cancers of the central and peripheral nervous system. Experts in neurosurgery, neuroradiology, neuropathology, neuro-oncology, and all other relevant fields present well-rounded, in-depth, cutting-edge information on epidemiology, diagnosis, and treatment for each type of tumor entity. This practical organization allows readers to efficiently access complete clinical knowledge on any form of neurological cancer.

This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects. The book shall provide valuable assistance to practicing neuro-oncologists to practice better evidence-based personalized medicine.

Neuro-oncologic (brain and spine) cancers account for 19,000 new cases and 13,000 deaths per year. The early and proper diagnosis of these virulent cancers is critical to patient outcomes and diagnosis and treatment strategies are continually evolving. The multidisciplinary team that manages these patients involves medical and radiation oncology, neurosurgery, neuroimaging, nurses and therapists. Principles and Practices of Neuro-Oncology establishes a new gold standard in care through a comprehensive, multidisciplinary text covering all aspects of neuro-oncology. Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive care, imaging, neuroanatomy and neurosurgery, medical oncology and targeted therapies, and radiation oncology for adult and pediatric cancers. Expert contributors from multiple disciplines provide detailed and in-depth discussions of the entire field of neuro-oncology including histopathologic harmonization, neurosurgical techniques, quality of life and cognitive functions, and therapeutic changes in terms of combined modality treatments, advanced radiation techniques, the advent of new drugs, especially targeted agents, and the tantalizing early promise of personalized therapeutic approaches. With contributions from over 180 authors, numerous diagrams, illustrations and tables, and a 48 page color section, Principles and Practice of Neuro-Oncology reflects the breadth and depth of this multi-faceted specialty.