Prion Biology And Diseases
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Prion Biology
Author | : Stanley B. Prusiner |
Publsiher | : Perspectives Cshl |
Total Pages | : 0 |
Release | : 2017 |
Genre | : Medical |
ISBN | : 1621820939 |
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"Prions are infectious proteins responsible for diseases such as Creutzfeldt-Jakob disease and "mad cow" disease. They are misfolded versions of normal proteins that replicate by converting their normal cellular counterparts into abnormal prion proteins that disrupt cell function and can be transmitted to other cells and individuals. This book exam
Prion Biology and Diseases
Author | : Stanley B. Prusiner |
Publsiher | : CSHL Press |
Total Pages | : 1130 |
Release | : 2004 |
Genre | : Prion diseases |
ISBN | : 0879696931 |
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This volume is a new edition of the most authoritative book on Prion Biology, first published in 1999 and edited by the Nobel Prize-winning founder of the field. This expanded edition has been completely updated, and includes chapters on therapeutics, and diagnostic methods and approaches.
Prions
Author | : Claudio Soto |
Publsiher | : CRC Press |
Total Pages | : 184 |
Release | : 2005-12-20 |
Genre | : Medical |
ISBN | : 9781420040128 |
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Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis. The horrific advent of Mad Cow Disease -- transmitted to humans through eating meat from steers sickened by bovine spongiform encephalopathy
Prions and Diseases
Author | : Wen-Quan Zou,Pierluigi Gambetti |
Publsiher | : Springer Science & Business Media |
Total Pages | : 246 |
Release | : 2012-11-27 |
Genre | : Medical |
ISBN | : 9781461453055 |
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Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer’s disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
Prion Biology and Diseases
Author | : Stanley B. Prusiner |
Publsiher | : Unknown |
Total Pages | : 816 |
Release | : 1999 |
Genre | : Medical |
ISBN | : UOM:39015048511466 |
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After initial skepticism, it is now generally accepted that prions exist, that they differ from all other pathogens, and that they are infectious in several species. Prions are implicated in spongiform encephalopathies such as kuru, Creutzfeldt-Jakob disease and fatal familial insomnia in humans, scrapie in sheep and a bovine encephalopathy that may be transmissible to humans. Driven by prions' novelty and by concern about their public health effects, awareness of these pathogens has grown enormously, prompting an immense amount of sometimes conflicting research.
Prions and Diseases
Author | : Wen-Quan Zou,Pierluigi Gambetti |
Publsiher | : Springer Science & Business Media |
Total Pages | : 322 |
Release | : 2012-11-08 |
Genre | : Medical |
ISBN | : 9781461453383 |
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Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
Prions and Diseases
Author | : Wen-Quan Zou,Pierluigi Gambetti |
Publsiher | : Springer Nature |
Total Pages | : 773 |
Release | : 2023-01-01 |
Genre | : Medical |
ISBN | : 9783031205651 |
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Transmissible spongiform encephalopathies (TSE), known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including the protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains by far the most authoritative views about the past, present, and future of prions and prion diseases. The new second edition covers such important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.
Prion Biology
Author | : Vincent Béringue |
Publsiher | : CRC Press |
Total Pages | : 283 |
Release | : 2013-04-08 |
Genre | : Science |
ISBN | : 9781926895376 |
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This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in mammals. There is also mounting evidence that studying prion biology has a wider relevance due to similarities in the processes of protein misfolding and aggregation between prion disorders and other neurodegenerative disorders such as Alzheimer’s, Parkinson’s, and Huntington’s diseases.