Radiation Therapy In Hematologic Malignancies

This book is designed to assist practitioners in managing patients who present with difficult cases of the most common hematological malignancies. The scenarios covered are those that are likely to be encountered in patients with the various forms of Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and leukemia. In each of the three sections devoted to these malignancies, multiple cases are presented. The case discussions follow a standard format. A clinical description is followed by a pathological description documenting information relevant to diagnosis and by details of staging work-up, including images. The treatment options are then discussed at length, highlighting relevant literature for each option. Finally, the treatment delivered is identified and images of the planning technique/modality used are provided. This book will be an invaluable aid to decision making for radiation oncologists and will also be of interest for hematologists.

Radiation Medicine Rounds is a trinary hard cover periodical designed to provide an up-to- date review of a dedicated radiation medicine topic of interest to clinicians and scientists who are involved in the care of patients receiving radiotherapy. It is intended to serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinicians, medical physicists, cancer biologists, radiobiologists, and interdisciplinary colleagues throughout the oncology spectrum. This issue of Radiation Medicine Rounds discusses the more salient topics surrounding the role of radiation therapy for hematologic malignancies. There are literally dozens of distinct lymphoma subtypes, each with its own unique molecular and clinical features. Although systemic cytotoxic and targeted therapies have improved dramatically, radiation therapy remains an important modality for optimal clinical outcomes. With contributions from nationally recognized experts, Hematologic Malignancies offers an overview of the full spectrum of therapy for hematologic malignancies ranging from lymphoma and leukemia to plasma cell dyscrasias. Recent advances in radiotherapy for hematologic malignancies allow for maintenance of excellent local control with improvements in toxicity achieved through reductions in field sizes, in dose delivered, and increasingly conformal delivery techniques. Hematologic Malignancies provides the practitioner with a current overview of best practices, recent research, and future directions in the management of these complex cancers.

This issue of PET Clinics focuses on PET in the Management of Hematologic Malignancies and is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Gary Ulaner, Jakub Svoboda, and Lale Kostakoglu. Articles will include: PET-CR as a surrogate to replace PFS in assessment of efficacy of DLBCL treatments; PET-Derived Quantitative Metrics for Response and Prognosis; Evolving Role of PET Based Novel Quantitative Techniques in the Management of Hematological Malignancies; Critical Role of FDG/NaF imaging in Assessment of Skeletal Involvement in Patients with Multiple Myeloma; Response adapted treatment strategies in Hodgkin lymphoma using PET scans; FDG PET/CT as a staging tool in multiple myeloma; FDG PET/CT as a predictor of prognosis in multiple myeloma; PET/CT as a response evaluation tool in multiple myeloma; PET imaging in CLL and Richter’s transformation; Current Overview and Future Directions of PET for Hematologic Malignancies; and more!

Radiation Medicine Rounds is a trinary hard cover periodical designed to provide an up-to- date review of a dedicated radiation medicine topic of interest to clinicians and scientists who are involved in the care of patients receiving radiotherapy. It is intended to serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinicians, medical physicists, cancer biologists, radiobiologists, and interdisciplinary colleagues throughout the oncology spectrum. This issue of Radiation Medicine Rounds discusses the more salient topics surrounding the role of radiation therapy for hematologic malignancies. There are literally dozens of distinct lymphoma subtypes, each with its own unique molecular and clinical features. Although systemic cytotoxic and targeted therapies have improved dramatically, radiation therapy remains an important modality for optimal clinical outcomes. With contributions from nationally recognized experts, Hematologic Malignancies offers an overview of the full spectrum of therapy for hematologic malignancies ranging from lymphoma and leukemia to plasma cell dyscrasias. Recent advances in radiotherapy for hematologic malignancies allow for maintenance of excellent local control with improvements in toxicity achieved through reductions in field sizes, in dose delivered, and increasingly conformal delivery techniques. Hematologic Malignancies provides the practitioner with a current overview of best practices, recent research, and future directions in the management of these complex cancers. "

With contributions by numerous experts

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

One of the first book’s to deal specifically with imaging of the entire spectrum of hematological malignancies. The use of the latest imaging modalities is well described, and an important aspect of the book is the role of imaging techniques in differentiating between manifestations of the underlying disease and complications of treatment. Each of the 28 chapters is written by an internationally recognized expert, making this book the most current and complete treatment of this subject available. Includes many high-quality radiological and histological illustrations. It should be of great interest to radiologists and hematologists.

Hematologic malignancies, also known as blood cancers, refer to a wide range of cancers that originate in the bone marrow or the lymphatic system. These cancers can affect the production and function of blood cells, including white blood cells, red blood cells and platelets. Hematologic malignancies include leukemia, lymphoma, and multiple myeloma. The treatment of hematologic malignancies depends on the specific type and stage of the cancer, as well as individual patient factors. These malignancies can be treated through radiation therapy, chemotherapy, immunotherapy, targeted therapy and stem cell transplantation. Radiation therapy uses high-energy radiation to target and kill cancer cells. Chemotherapy makes use of powerful medications to destroy cancer cells or prevent their growth. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of hematological malignancies. It will serve as a valuable source of reference for graduate and postgraduate students.