Recovery From Radiation Damage In Biological Systems

Modern Trends in Physiological Sciences, Volume 7: Radiation Protection and Recovery covers the biological, physiological, and biochemical methods created to protect living organisms from radiation damage. This book is composed of 12 chapters that evaluate the methods of protecting macromolecules in vitro against ionizing radiation damage. It addresses the degradation of polymethacrylic acid and the polymerization of vinyl monomers. Some of the topics covered in the book are the chemical protection to mammals against ionizing radiation; chemical protective agents; methods of protection and recovery in bacteria and fungi; and effect of cultural conditions and physiological state on radiosensitivity. Other chapters deal with the experimental modification of radiosensitivity and the role of phase state in inactivitation. These topics are followed by an analysis of the effect of the gaseous environment during irradiation. The chemical protection against inactivation and mutation is also presented. The last chapter is devoted to the environmental factors in radioresistance. The book can provide useful information to doctors, radiologists, students, and researchers.

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

The book is concerned with features analysis of radiation damage to living matter at different levels of its organisation, beginning from the molecular level. The general theory of the mechanisms of biological action of radiation based on four logically connected principles of radiation biology is presented for the first time. The book contains abundant material on primary and secondary processes of the response of living systems to radiation, the mechanisms of direct and indirect action of radiation through radiolysis of water and lipids; a detailed consideration of the theory of targets (DNA and biological membranes) and the problems of high- and low-dose irradiation in the context of present-day. The systemic response of the cell to irradiation (oxidative stress, endogenous background radioresistance, damage and repair of biological membranes and DNA, systemic protection against radiation) is approximated. Presentation of these important problems is preceded by an up-to-date evaluation of some aspects regarding dosimetry of ionising radiation.

A practical guide for medical physicists and those whose work involves any aspect of hospital radiation protection. It provides guidance on methods that may be used to tackle the tasks that a physicist working in this area might encounter.