Regenerative Medicine In China

This book includes major issues in wound tissue repair and regeneration in 14 chapters. The topics start from cytological basis, molecular and genetic basis, skin development, to the tissue repair, visceral injury and tissue engineering. In the second part, it introduces Chinese researchers’ contribution in wound repair and regeneration. Specially, it has 3 chapters discussing new technologies in tissue repair and regeneration, and 1 chapter in Traditional Chinese Medicine.

As the world’s population ages, the problem of degenerative disease is increasing. At the same time, the demand for organ transplants to repair or replace damaged tissue continues to grow. Regenerative medicine is a branch of translational medicine which promotes the repair, regeneration, or construction of tissues and organs or improves or restores their function through tissue engineering, cell biology, molecular biology and other techniques. Stem cells are one of the most important types of cells used in regenerative medicine, and stem cell research is also one of the most active research areas in the field. This book presents 20 full papers from the 8th International Symposium China-Europe “Stem Cells and Regenerative Medicine”, held in Wuhan, China from 19-21 June 2018. At this symposium, researchers in the field of stem cells and regenerative medicine from China and France discussed research from a molecular point of view and pointed out the clinical applications of mesenchymal stem cells, as well as the construction and applications of new biomaterials, the biomechanics of bone tissue engineering, and cellular immunotherapy, among other subjects. Stem cell technology could soon make possible the repair or replacement of aging and damaged tissue, as well as providing a treatment for genetic defects and malignancies,and this book will be of value to all those with an interest in regenerative medicine.

Most human tissues do not regenerate spontaneously, but the development of biotherapies using stem cells may offer promising alternatives. Among the possible medium-term therapeutic applications for this technique are: cardiac insufficiency, preparation of small diameter arteries, treatment of atherosclerosis, bone repair, cartilage defects, burns, diabetes, liver or bladder regeneration, and neurodegenerative disorders. This concept of regenerative medicine is an emerging multidisciplinary field involving surgery medicine, biology, chemistry, mechanics and engineering, and can be seen as a way of improving health and quality of life by restoring, maintaining, or enhancing tissue and organ function. This book presents the proceedings of the 9th China-France Symposium on Stem Cells and Regenerative Medicine, held in Strasbourg, France, from 2-4 October 2019.The aim of the symposium was to provide researchers, clinicians and students with a comprehensive, up-to-date overview of stem cells and potential medical applications in cellular and tissue engineering for the treatment of various chronic diseases. It also brought together scientists from various disciplines and experiences to discuss recent advances in the use and applications of stem cells. The contributions presented here divide into three main themes: cells; tissue engineering; and clinical applications. Important complementary aspects such as ethics and cell marketing are also discussed. Illustrating the challenges and recent progress achieved in the characterization of stem cells, the book will be of interest to all those working in the field.

This book provides a comprehensive review of the properties of various stem cell types, the mechanisms of their behaviors and their potential clinical application. Stem cells have a great capacity of self-renewal and differentiation. They represent new paradigms for disease treatment in the field of regenerative medicine since the day they were discovered. As stem cell research is complicated and making progress rapidly, it is important to have expertise in this field to share their views and perspectives. This book provides a wonderful platform for those who are interested in stem cells to learn from and communicate with experts. Particularly, it highlights the roles of stem cell based therapy for a variety of diseases. Furthermore, this book gives a detailed introduction to the great works related to stem cells in China. The readers could gain a profound knowledge of the state-of-art research done by scientists in the field of stem cells. Overall, this book will be a valuable reference resource for both experienced investigators pursuing stem cell research as well as those are just entering into this field. Dr. Robert Chunhua Zhao, a Cheung Kong Professor of Stem Cell Biology, is Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College (PUMC), Beijing, China. He is Director of the Center for Tissue Engineering, PUMC and Chief Scientist of the National Basic Research Program of China ("973 Program"). He also serves as Regional Editor of Stem Cells and Development.

The book focuses on the application of nanotechnologies in scaffold-guided tissue regeneration and in drug delivery systems for use in immunotherapy and overcoming drug resistance in cancer treatment. It covers a variety of topics, including nanomaterials for immunomodulation and immnunotherapy; molecular studies on self-assembly for peptides and DNA and related applications in tumor diagnosis and therapeutics and against human pathogenic bacteria; magnetic and conductive scaffolds for guiding tissue regeneration; multiple functions of magnetic nanoparticles in drug delivery and regenerative medicine; and re-purposing of traditional medicine in nano-formulations. In addition, it discusses common effects of nanomaterials, including reactive oxygen species and protein corona. Providing valuable insights and the presenting the latest research advances, the book allows readers to gain a systematic understanding of the topic.

This book discusses different aspects of trauma surgery, ranging from the various types of trauma and their management, infection, sepsis and inflammation to tissue injury and repair in trauma. It discusses cellular, molecular and genetic research findings and their role in pathogenesis in trauma and injury. In addition, it highlights the translational application of advanced theories and technologies in the management of trauma patients. This book is a valuable resource for anyone involved in the management of severe trauma damage to tissues wanting to reduce early mortality and improve patients' quality of life.

This book provides a comprehensive review of the properties of various stem cell types, the mechanisms of their behaviors and their potential clinical application. Stem cells have a great capacity of self-renewal and differentiation. They represent new paradigms for disease treatment in the field of regenerative medicine since the day they were discovered. As stem cell research is complicated and making progress rapidly, it is important to have expertise in this field to share their views and perspectives. This book provides a wonderful platform for those who are interested in stem cells to learn from and communicate with experts. Particularly, it highlights the roles of stem cell based therapy for a variety of diseases. Furthermore, this book gives a detailed introduction to the great works related to stem cells in China. The readers could gain a profound knowledge of the state-of-art research done by scientists in the field of stem cells. Overall, this book will be a valuable reference resource for both experienced investigators pursuing stem cell research as well as those are just entering into this field. Dr. Robert Chunhua Zhao, a Cheung Kong Professor of Stem Cell Biology, is Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College (PUMC), Beijing, China. He is Director of the Center for Tissue Engineering, PUMC and Chief Scientist of the National Basic Research Program of China (“973 Program”). He also serves as Regional Editor of Stem Cells and Development.

Young Joy, who has been experiencing the stifling control of the Chinese government over the lofty ambitions of university students like herself to study abroad, has just realized that the forces amassed against her won't budge a millimeter despite her efforts to work within the system. So Joy initiates a complex series of daring scenarios to beat the legal system at its own game in order to secure her exit visa to the United States. And she does: transforming herself into the Tiger of Beijing. Calculated. Intuitive. Fierce. But before her plane lands in the Land of Opportunity, Joy finds herself faced with another problem that proves to be much more challenging than leaving a Communist country. Psychologically pushed to the brink of ruin in every way imaginable, Joy once again calls forth the Tiger of Beijing from deep within herself. Set against the austere backdrop of the post-Tiananmen Square Incident in Beijing, China, Tiger of Beijing dramatically relays Joy's five-year hero's journey that takes her across the Atlantic and into the heart of San Francisco where she finally experiences the freedom of the human spirit for which she had longed as a young girl.