Regions Of The Heart

Discover the powerful story of one woman's lifelong dedication to adventure and determination to succeed, as featured in the brand new BBC2 documentary The Last Mountain 'I shed a tear as I read this . . . I'll admit that I did not do so when I originally heard of her death. The difference? This book' INDEPENDENT ______ Alison Hargeaves was one of the finest climbers of her generation. But in 1995, she died during a violent storm on K2. On her death she was vilified by media outrage that a wife and mother would take such extreme risks. This is the story of a woman with an astonishing determination to be the best that she could. A woman driven to succeed just to secure a future for herself and her family. ______ 'A riveting and incredibly moving story' Irish News 'Few realized the extent of her inner turmoil - and her courage. A very moving biography of an extraordinary woman with an extraordinary talent and determination' Daily Telegraph 'A sensitive and intelligent book . . . Rose and Douglas recuse Hargreaves from the crude distortions of those who wanted to vilify or venerate her' Sunday Telegraph

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

K2 is the second highest mountain in the world, at 8611 metres only a couple of hundred metres lower than Everest. It is one of the most unrelenting and testing of the worlds 8000-metre peaks. Jim Curran came to K2 as a climbing cameraman with an unsuccessful British expedition, but stayed on through the climbing season. This is his account of the dramatic events of that summer, a story of ambitions both achieved and thwarted on a mountain which all high-altitude climbers take the most pride in overcoming. In 1986 K2 took its toll of those ambitions. Curran vividly describes the moments that contribute to the exhilaration of climbing on the world's most demanding mountain, and he assesses the tragedy of that summer with compassion and impartiality.

One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.

Hearts have no template: they vary as much as snowflakes. Like snowflakes, some hearts are cold, but others are warm as babies’ hands. Some are gray with melancholy; some bright with good cheer. This collection contains poems that reflect moments of the heart’s delight and struggle. Some of the poems are indirect, merely suggesting the presence of the heart. Some are happily frivolous, as hearts can be; others are drawn from deep wells. Yet others squeeze into the group, altogether heartless, having slipped in between pulsations.

Heart of Darkness is often considered the world’s best short novel. The book serves as a bridge between the 19th century and modernism, an adventure tale revolving around the ambiguity of themes such as truth, morality, and evil. Joseph Conrad witnessed the European exploitation of the Congo with his own eyes. He once sailed up the Congo River himself to locate a countryman at a trading station deep within the country – even though this man wasn't named Kurtz. The goal and enigma of the journey have become synonymous with this name, one of the most unforgettable fictional characters of our time. JOSEPH CONRAD [1857–1924] was born in Ukraine to Polish parents, went to sea at the age of seventeen, and ended his career as a captain in the English merchant navy. His most famous work is the novella Heart of Darkness [1899], adapted into a film by Francis Ford Coppola in 1979 as Apocalypse Now.