Reinventing Discovery

"Reinventing Discovery argues that we are in the early days of the most dramatic change in how science is done in more than 300 years. This change is being driven by new online tools, which are transforming and radically accelerating scientific discovery"--

How the internet and powerful online tools are democratizing and accelerating scientific discovery Reinventing Discovery argues that we are living at the dawn of the most dramatic change in science in more than three hundred years. This change is being driven by powerful cognitive tools, enabled by the internet, which are greatly accelerating scientific discovery. There are many books about how the internet is changing business, the workplace, or government. But this is the first book about something much more fundamental: how the internet is transforming our collective intelligence and our understanding of the world. From the collaborative mathematicians of the Polymath Project to the amateur astronomers of Galaxy Zoo, Reinventing Discovery tells the exciting story of the unprecedented new era in networked science. It will interest anyone who wants to learn about how the online world is revolutionizing scientific discovery—and why the revolution is just beginning.

This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.

Consider the complexity of a living cell after 3.8 billion years of evolution. Is it more awesome to suppose that a transcendent God fashioned the cell at a stroke, or to realize that it evolved with no Almighty Hand, but arose on its own in the c...

"The Creativity Crisis excavates the root causes of America's innovation slow-down, showing why revolutionary insights are no longer chased by young talent. Economically and socially, caution has overtaken creation. This book is ultimately a roadmap for reinvigorating innovation within the system of science"--

The author of The Eudaemonic Pie now reveals the inspiration, motivations, and aspirations of the world's greatest scientists. The scientists interviewed in this collection have changed the rules of the game--altered our perception of reality and the language used to describe it.

Lead students through powerful learning experiences with Reinventing Project-Based Learning, a guide for educators, administrators and professional development specialists who want to make the shift to a more student-driven learning model. Explore proven strategies for overcoming the limitations of the traditional classroom, including a wealth of technology tools for inquiry, collaboration and global connection to support this new vision of instructional design.