Research Methodology In The Medical And Biological Sciences

Providing easy-to-access information, this unique sourcebook covers the wide range of topics that a researcher must be familiar with in order to become a successful experimental scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences it discusses a broad range of topics that are common, yet not traditionally considered part of formal curricula. The information presented also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. Perfect for students with various professional backgrounds providing a broad scientific perspective Easily accessible, concise material makes learning about diverse methods achievable in today's fast-paced world

Research in Medical and Biological Sciences covers the wide range of topics that a researcher must be familiar with in order to become a successful biomedical scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences, this publication discusses a broad range of topics that are common yet not traditionally considered part of formal curricula, including philosophy of science, ethics, statistics, and grant applications. The information presented in this book also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. Covers the breadth of topics that a researcher must understand in order to be a successful experimental scientist Provides a broad scientific perspective that is perfect for students with various professional backgrounds Contains easily accessible, concise material about diverse methods Includes extensive online resources such as further reading suggestions, data files, statistical tables, and the StaTable application package Emphasizes the ethics and statistics of medical and biological sciences

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

My original intention was to write a history of medical statistics, used in its prewar sense, expanding the writings on the subject by Major Greenwood, from which I formed many of my ideas in the early days immediately after the Second World War. In later years, I decided that the scope of his works was narrower than what I think is appropriate now, for he was writing in an era before the acceptance and use of the Fisherian methods and he was probably not aware of the mathematization of many parts of biological theory. Further, the boundary between the medical and biological sciences has largely disappeared. Many texts have now been written on branches of the theory and practice inspired by R. A. Fisher (see §4. 13). I discuss the history of the use of quantitative methods in the biological sciences, defined after the style of Peller (1967) as that branch of science that uses a quantitative approach to, or quantitative logical reasoning on, or biology. The mathematical tech any issue having to do with medicine niques are various and not classified here. Within the book I use "biological sciences" to include medicine but use the longer phrase in its title to avoid misunderstandings as to content. Moreover, most of the experimental work carried out in medical research laboratories is performed on animals other than man.

This book discusses the why and how of each step of data-based medical research that can provide basic information to emerging researchers and medical graduate students who write theses or publish articles. The chapters are arranged in the sequence of steps for data-based research. The research steps are comprehensively covered from the selection of the topic to the final publication. Reporting methods such as CONSORT, STARD, and SAMPL guidelines are also covered. Each chapter has separately earmarked examples from the contemporary literature that illustrate the different research methods. Key Features Discusses all the steps of data-based medical research Examines the topics in depth by way of examples from contemporary literature Features notable information in boxes for special attention .

Advances in Biological Science Research: A Practical Approach provides discussions on diverse research topics and methods in the biological sciences in a single platform. This book provides the latest technologies, advanced methods, and untapped research areas involved in diverse fields of biological science research such as bioinformatics, proteomics, microbiology, medicinal chemistry, and marine science. Each chapter is written by renowned researchers in their respective fields of biosciences and includes future advancements in life science research. Discusses various research topics and methods in the biological sciences in a single platform Comprises the latest updates in advanced research techniques, protocols, and methods in biological sciences Incorporates the fundamentals, advanced instruments, and applications of life science experiments Offers troubleshooting for many common problems faced while performing research experiments

Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.

My original intention was to write a history of medical statistics, used in its prewar sense, expanding the writings on the subject by Major Greenwood, from which I formed many of my ideas in the early days immediately after the Second World War. In later years, I decided that the scope of his works was narrower than what I think is appropriate now, for he was writing in an era before the acceptance and use of the Fisherian methods and he was probably not aware of the mathematization of many parts of biological theory. Further, the boundary between the medical and biological sciences has largely disappeared. Many texts have now been written on branches of the theory and practice inspired by R. A. Fisher (see §4. 13). I discuss the history of the use of quantitative methods in the biological sciences, defined after the style of Peller (1967) as that branch of science that uses a quantitative approach to, or quantitative logical reasoning on, or biology. The mathematical tech any issue having to do with medicine niques are various and not classified here. Within the book I use "biological sciences" to include medicine but use the longer phrase in its title to avoid misunderstandings as to content. Moreover, most of the experimental work carried out in medical research laboratories is performed on animals other than man.