Retinal Degeneration

This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

Age-related macular degeneration is the most important cause of visual impairment in the elderly. The non-exudative or dry form progresses slowly, the exudative or wet form rapidly (within weeks or months). Refer a patient with suspected exudative form of the disease without delay for investigations and treatment. Also consider the significance of the disease in the patients' daily life.

This book provides an illustrated guide to peripheral retinal degenerations and the role of spectral domain coherence tomography (SD-OCT) in diagnosis and treatment. The book discusses 73 clinical cases and gives detailed information on the principles of SD-OCT and its application in the imaging of peripheral retina. Peripheral Retinal Degenerations: Optical Coherence Tomography and Retinal Laser Coagulation, 2nd edition, discusses a broad range of retinal pathologies such as chorioretinal degenerations, posterior vitreous detachment, vitreoretinal adhesions and tractions and includes a plethora of high-quality clinical images throughout. Ophthalmologists and retinal specialists will find this updated edition to be the perfect didactic resource for furthering skills and knowledge in this clinical area.

The acclaimed book on macular degeneration—now completely revised and updated with cutting edge research and the latest developments in the field. More than fifteen million Americans have age-related macular degeneration (AMD), and the disease will strike 200,000 more people this year. It is the most prevalent cause of vision loss in the western world. Dr. Lylas Mogk, the founding director of the Visual Rehabilitation and Research Center of the Henry Ford Health System, has a unique professional and personal understanding of AMD. A doctor and loving daughter of a parent with this frightening though manageable condition, Mogk here explains exactly what it is and how to limit its effect on your life. Reassuring and comprehensive—complete with illuminating first person stories of people with AMD—Macular Degeneration will help you or someone you love with information on • Reducing your risk factors • Revolutionary new technology, including laser surgery and alternative treatments • New research discoveries in nutrition—and eye-healthy recipes • The latest low-vision computer software programs • Coping with depression and frustration • Active online communities of people with macular degeneration Plus a Low Vision Living Rehab program to help you read better, see better, and live independently!

Showcases exudative and nonexudative AMD treatment techniques using argon and diode lasers, submacular and macular translocation surgery, photodynamic therapy, radiation, feeder vessel treatment, thermotherapy, and antiangiogenesis drugs. Includes 160 color illustrations. Showcases exudative and nonexudative AMD treatment techniques using ar

Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.

This edited book focuses on the recent advances in our understanding of age-related macular degeneration (AMD), combining epidemiology and clinical diagnosis, with genetics and immunological aspects as well as the role of proteostasis and mitochondria before diving into new therapies including stem cell based approaches. AMD is a leading cause of largely incurable blindness worldwide and projected to double from 2.07 million to 5.44 million individuals by 2050 in the United States. Globally, 288 million individuals are projected to have AMD by 2040. The disease has enormous socioeconomic impact on the affected individuals, their families and the society. This book will bring together the state of the art basic science knowledge with clinically relevant findings and address the challenges for future research in AMD. The intersection of different disciplines will provide potential areas for further investigations to reduce the burden of blindness from AMD. This book offers an appealing and insightful resource for clinicians, scientists, students and fellows.