Safety Evaluation Of Certain Mycotoxins In Food

This volume contains monographs prepared at the fifty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). Five mycotoxins or groups of mycotoxins that contaminate food commodities were evaluated at the meeting: aflatoxin M1, fumonisins B1, B2, and B3, ochratoxin A, deoxynivalenol, and T -2 and HT -2 toxins. The monographs in this volume summarize the data that were reviewed on these contaminants, including information on metabolism and toxicity, epidemiology, analytical methods for their measurement in food commodities, sampling protocols, effects of processing, levels and patterns of contamination of food commodities, food consumption, and prevention and control. Based upon this information the Committee assessed the risks associated with intake of these mycotoxins.

This report presents the conclusions of a joint expert committee convened to assess the risks associated with the consumption of food contaminated with specific mycotoxins. It contains a general discussion of the principles for evaluating mycotoxins in food, including those concerning analytical methods, sampling, data on food consumption and dietary intake, and prevention and control.

This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavoring agents with a view to recommending acceptable daily intakes (ADIs) and to preparing specifications for identity and purity. The Committee also evaluated the risk posed by two food contaminants with the aim of advising on risk management options for the purpose of public health protection. Annexed to the report are tables summarizing the Committee's recommendations for intakes and toxicological evaluations of the food additives and contaminants considered.

Mycotoxins, toxic compounds produced by fungi, pose a significant contamination risk in both animal feed and foods for human consumption. With its distinguished editors and international team of contributors, Mycotoxins in food summarises the wealth of recent research on how to assess the risks from mycotoxins, detect particular mycotoxins and control them at differing stages in the supply chain. Part one addresses risk assessment techniques, sampling methods, modelling and detection techniques used to measure the risk of mycotoxin contamination and the current regulations governing mycotoxin limits in food. Part two looks at how the risk of contamination may be controlled, with chapters on the use of HACCP systems and mycotoxin control at different stages in the supply chain. Two case studies demonstrate how these controls work for particular products. The final section details particular mycotoxins, from ochratoxin A and patulin to zearalenone and fumonisins. Mycotoxins in food is a standard reference for all those concerned with ensuring the safety of food. Discusses the wealth of recent research in this important area Covers risk assessment, detection of particular mycotoxins and how to control them throughout the supply chain Describes how the risk of contamination can be controlled, including the use of HACCP systems

This book evaluates the design and findings of studies relevant to the safety assessment of selected food additives and contaminants. The book, which is part of a long-running series prepared by the Joint FAO/WHO Expert Committee on Food Additives (JECFA), gives toxicologists, the food industry, and regulatory agencies a record of the scientific evidence considered when the Committee allocates or revises acceptable daily intakes and other endpoints. Emphasis is placed on studies that relate specific exposure levels to specific toxic effects or guide the meaningful extrapolation of animal data to the human condition. Through its careful attention to questions of study design, methodology, and the validity of reported data, the book also demonstrates the strict safety standards used by JECFA in its efforts to protect consumers from any possible toxicological or pharmacological hazard linked to the use of food additives. Separate toxicological monographs are presented for one glazing agent (hydrogenated poly-1-decene), one sweetening agent (erythritol), one thickener (curdlan), and three miscellaneous substances ( g-cyclodextrin, sodium iron ethylenediamine tetraacetic acid (EDTA), and sodium sulfate). The volume also includes monographs on two groups of related substances evaluated according to the Procedure for the Safety Evaluation of Flavouring Agents, and on the allergenicity potential of peanut and soya bean oils. Subsequent monographs summarize the toxicological and intake data available for three food contaminants (lead, methylmercury, and zearalenone), and the intake data available for four food additives (annatto extracts (bixin), canthaxanthin, erythrosine, and iron oxides).

Full text, included in Knovel Library within the subject area of Chemistry and Chemical Engineering.