Science And Technology Against Microbial Pathogens

The aim of this book is to disseminate the most recent research in science and technology against microbial pathogens presented at the first edition of the ICAR Conference Series (ICAR2010) held in Valladolid, Spain, in November 2010. This volume is a compilation of 86 chapters written by active researchers that offer information and experiences and afford critical insights into anti-microbe strategies in a general context marked by the threat posed by the increasing antimicrobial resistance of pathogenic microorganisms. “Anti” is here taken in a wide sense as “against cell cycle, adhesion, or communication”, and when harmful for the human health (infectious diseases, chemotherapy etc.) and industry or economy (food, agriculture, water systems etc.) The book examines this interesting subject area from antimicrobial resistance (superbugs, emerging and re-emerging pathogens etc.), to the use of natural products or microbes against microbial pathogens, not forgetting antimicrobial chemistry, physics and material science. Readers will find in a single volume, up-to-date information of the current knowledge in antimicrobial research. The book is recommended for researchers from a broad range of academic disciplines that are contributing in the battle against harmful microorganisms, not only those more traditionally involved in this research area (microbiologists, biochemists, geneticists, clinicians etc.), but also experimental and theoretical/computational chemists, physicists or engineers. Contents:Antimicrobial Peptides:A new class of Scots pine antimicrobial proteins, which act by binding β-glucan (Sanjeewani Sooriyaarachchi, Adrian Suárez Covarrubias, Wimal Ubhayasekera, Frederick O Asiegbu and Sherry L Mowbray)Antimicrobial aza-β3-peptides: Structure-activity relationship? (B Legrand, M Laurencin, C Zatylny-Gaudin, J Henry, A Bondon and M Baudy Floc'h)Differential antimicrobial activities of Human Beta-Defensins against Methicillin Resistant (MRSA) and Methicillin sensitive (MSSA) Staphylococcus aureus (N D S Herathge, J T George and D A Rowley)Non-antibiotics Biocides:Evaluation of biocidal activity of Evolyse, a disinfectant based on hydrogen peroxide and silver nitrate (M Barbara Pisano, V Altana, M Elisabetta Fadda, L Mura, M Deplano and S Cosentino)Increased resistance to detergent in Enterococcus faecalis (Jacqueline Keyhani and Ezzatollah Keyhani)Legionella pneumophila isolation rate in a Spanish hospital pre- and post-installation of an electrochemical activation system for potable water disinfection (Jose-Maria Rivera, Juan-Jose Granizo, Jose-Maria Aguiar, Ana Vos-Arenilla, Maria-Jose Giménez and Lorenzo Aguilar)Antimicrobial Evaluation: Clinical and Pre-clinical Trials:Adherence to ART and its associated factors among HIV Aids Patients in Addis Ababa (Ezra Muluneh)Effectiveness and safety of miconazole with hydrocortisone (Daktacort) feminine care cream in the treatment of vulvar candidiasis (J Perez-Peralta and G Balaccua)Natural Products: Terrestrial and Marine Organisms:Analysis of the 2-Phenylethyl isothiocyanate present in Brassica leaves and their potential application as antimicrobial agent against bacteria strains isolated from Human and Pig gastrointestinal tracts (A Aires, C Dias, R N Bennett, E A S Rosa and M J Saavedra)Antimicrobial effect of carvacrol on Escherichia coli K12 growth at different temperatures (C M Belda-Galbis, A Martínez and D Rodrigo)Bacteriostatic effect of cocoa powder rich in polyphenols to control Cronobacter sakazakii proliferation on infant milk formula (M C Pina-Pérez, D Rodrigo and A Martínez-López)Antimicrobial Surfaces. Biofilms. Quorum Sensing. Consumer Products:Antimicrobial active packaging films based on sorbic acid (C Hauser, J Wunderlich and G Ziegleder)Bacteriophages actions on Salmonella Enteritidis biofilm (A A Ferreira, R C S Mendonça, H M Hungaro, M M Carvalho and J A M Pereira)Biocompatibility and antibacterial property of cold sprayed ZnO/Titanium composite coating (Noppakun Sanpo, Chen Hailan, Kelvin Loke, Koh Pak Keng, Philip Cheang, C C Berndt and K A Khor)Methods and Techniques. Mechanisms of Action. Physics:A new approach for detection of bacterial contamination in cooling lubricants (D Oberschmidt, A Spielvogel, C Hein, J E Langbein, D Lorenz, U Stahl and E Uhlmann)Development of a liquid-medium assay for screening antimicrobial natural products against marine bacteria (M Geiger, J Dupont, O Grovel, Y F Pouchus and P Hess)Experimental planning can help to optimize the selective photoinactivation of microorganisms (J R Perussi, P L Fernandes, C Bernal and H Imasato)Resistance and Susceptibility:A 3-year review on the profile of multidrug-resistant Gram-negative in a tertiary teaching hospital inMalaysia (H Habsah, Z Z Deris, M Zeehaida, A R Zaidah, H Siti Asma' and I Nabilah)Antimicrobial susceptibility in clinical isolates of Staphylococcus aureus harbouring of mecA and lukFS-PV genes in Northern Portugal (N Silva, C Prudêncio, C Tomaz and R Fernandes)Antimicrobial susceptibility profile and effect of stem bark extracts of Curtisia dentata on multi-drug resistant verotoxic Escherichia coli and Acinetobacter spp. isolates obtained from water and wastewater samples (Hamuel James Doughari, Patrick Alois Ndakidemi, Izanne Susan Human and Spinney Benade)Chemistry:Antimicrobial cyclic pseudopeptides including Aza-β3-amino acids (M Laurencin, B Legrand, L Mouret, A Bondon, Y Fleury and M Baudy Floc'h)Effect of paracetamol on the pharmacokinetics of cephalexin in dogs (N A Afifi, M Atef, K Abo-El-Sooud and N El-Mokadem)Importance of the C9 absolute configuration for the antifungal activity of natural and semisynthetic sesquiterpenes (M Derita, M Di Liberto and S Zacchino)Antimicrobial Microbes and Viruses. Biosynthesis of Antibiotics:Antimicrobial properties of Lactobacillus plantarum Tensia (DSM 21380) and Inducia (DSM 21379) (M Rätsep, P Hütt, R Avi, M Utt and E Songisepp)Cell growth control by tRNase ribotoxins from bacteria and yeast (Eyemen Kheir, Christian Bär, Daniel Jablonowski and Raffael Schaffrath)Comparison of anti-listerial effect spectrum of bacteriocins (Selin Kalkan, Emel Ünal and Zerrin Erginkaya)and other papers Readership: Professionals - microbiologists, biochemists, geneticists, clinicians, chemists, physicists, engineers. Keywords:Antimicrobial Research;Antimicrobial Resistance;Antimicrobial in Natural Products;Antimicrobial Microbes;Antimicrobial Materials Science and Surface Chemistry;Microbial Pathogens;Antibacterial;Antifungal;ICAR2010 Conference Proceedings Book;Mendez-VilasKey Features:The book examines this interesting subject area from antimicrobial resistance (superbugs, emerging and re-emerging pathogens etc.), to the use of natural products or microbes against microbial pathogens, not forgetting the antimicrobial chemistry, physics and material scienceReaders will be able to find updated information of the current knowledge in antimicrobial research

This book aims to disseminate recent findings in the fight against microbial pathogens which were presented at the second edition of the ICAR Conference Series (ICAR2012) on Antimicrobial Research, held in Lisbon, Portugal, November 2012, which attracted about 425 scientists from 55 countries. This forum was the natural continuation of this new series of conferences: the first edition, held in Valladolid, Spain in 2010, gathered more than 500 researchers from nearly 60 countries. ICAR aims at establishing itself as a key forum in Europe for the presentation, exchange, and dissemination of information and experiences on anti-microbe strategies. "Anti" is here taken in the broadest sense as "against cell cycle, adhesion, or communication," when harmful for the human health, industry or economy (e.g. infectious diseases, chemotherapy, food, biomedicine, agriculture, livestock, biotechnology, water systems). Topics on antimicrobial natural products, antimicrobial resistance, antimicrobial surfaces, as well as methods and techniques, are included. This volume is a compilation of chapters written by active researchers that will provide readers with an up-to-date information about the current knowledge on antimicrobials in a worldwide context marked by the threat posed by the increasing antimicrobial resistance of microbial pathogens.

Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Multidisciplinary Approaches for Studying and Combating Microbial Pathogens offers the opportunity to learn about recent findings in the fight against microbial pathogens. This book contains a compilation of papers presented at the III International Conference on Antimicrobial Research (ICAR2014), held in Madrid, Spain, in October 2014. The papers are written by researchers from around the world and focus on several themes: antimicrobial natural products, biofilms, antimicrobial surfaces, antimicrobial resistance, clinical and medical microbiology. Readers will hopefully find this set of papers interesting and representative of the worldwide current knowledge on antimicrobial research.

The aim of this book is to disseminate the most recent research in science and technology against microbial pathogens presented at the first edition of the ICAR Conference Series (ICAR2010) held in Valladolid, Spain, in November 2010. This volume is a compilation of 86 chapters written by active researchers that offer information and experiences and afford critical insights into anti-microbe strategies in a general context marked by the threat posed by the increasing antimicrobial resistance of pathogenic microorganisms. "Anti" is here taken in a wide sense as "against cell cycle, adhesion, or communication," and when harmful for the human health (infectious diseases, chemotherapy etc.) and industry or economy (food, agriculture, water systems etc.) The book examines this interesting subject area from antimicrobial resistance (superbugs, emerging and re-emerging pathogens etc.), to the use of natural products or microbes against microbial pathogens, not forgetting antimicrobial chemistry, physics and material science. Readers will find in a single volume, up-to-date information of the current knowledge in antimicrobial research. The book is recommended for researchers from a broad range of academic disciplines that are contributing in the battle against harmful microorganisms, not only those more traditionally involved in this research area (microbiologists, biochemists, geneticists, clinicians etc.), but also experimental and theoretical/computational chemists, physicists or engineers.

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

This book focuses on successful application of microbial biotechnology in areas such as medicine, agriculture, environment and human health.

Advancements and Technologies in Pig and Poultry Bacterial Disease Control provides the most up-to-date knowledge on the tools and technologies used in the economics, prevention, monitoring and control of the most important bacterial diseases in these two important livestock species. Written by international experts in veterinary medicine, veterinary science, agricultural economics and environmental monitoring, this book provides state-of-the-art information regarding the application of technology to the prevention and control of bacterial disease in pigs and poultry. It presents the most up-to-date information on the major bacterial pathogens, why they are important, their epidemiology, pathogenesis and molecular basis of their virulence. Additional sections examine how genomic sequencing addresses the development of disease biomarkers for faster and highly specific diagnosis and how next generation sequencing can identify good and bad microflora. This book will be a valuable resource for veterinarians, epidemiologists, animal scientists, technologists, and researchers studying precision livestock farming. Students in veterinary, animal science and bio-science courses will also find it useful for its coverage of diseases and monitoring tools. Highlights crossover technologies from human to veterinary medicine, including the use of bioinformatics and genomics for disease prevention Uses results from the EU FP7-funded ProHealth project, the largest of its type ever awarded by the EU Examines how genomic analysis via next generation sequencing and microarray platforms can be exploited to develop novel biomarkers of bacterial disease in animals Reports on novel environmental monitoring tools and their use in determining disease threshold levels within herds and flocks