Science Findings

One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Many of the scientific breakthroughs of the twentieth century were first reported in the journal Nature. A Century of Nature brings together in one volume Nature's greatest hits—reproductions of seminal contributions that changed science and the world, accompanied by essays written by leading scientists (including four Nobel laureates) that provide historical context for each article, explain its insights in graceful, accessible prose, and celebrate the serendipity of discovery and the rewards of searching for needles in haystacks.

In the latest of TIME's extraordinary volumes on scientific discoveries, this special edition curates the 100 most impactful recent breakthroughs across 10 disciplines. Through sharp photos and TIME's peerless reporting, readers will explore the most captivating news and revelations in technology, botany, archaeology, genetics, zoology, the Earth, the mind, the cosmos, medicine and chemistry. Among the highlights:How to curb Alzheimer's disease with small lifestyle changesControversial findings about newfound human ancestors known as the HobbitsHigh-tech solutions to diabetes careThe gene-editng technique known as CRISPR, and the ethical questions behind itWhy the plight of the honeybee matters

This book provides an authoritative insight on the Loss and Damage discourse by highlighting state-of-the-art research and policy linked to this discourse and articulating its multiple concepts, principles and methods. Written by leading researchers and practitioners, it identifies practical and evidence-based policy options to inform the discourse and climate negotiations. With climate-related risks on the rise and impacts being felt around the globe has come the recognition that climate mitigation and adaptation may not be enough to manage the effects from anthropogenic climate change. This recognition led to the creation of the Warsaw International Mechanism on Loss and Damage in 2013, a climate policy mechanism dedicated to dealing with climate-related effects in highly vulnerable countries that face severe constraints and limits to adaptation. Endorsed in 2015 by the Paris Agreement and effectively considered a third pillar of international climate policy, debate and research on Loss and Damage continues to gain enormous traction. Yet, concepts, methods and tools as well as directions for policy and implementation have remained contested and vague. Suitable for researchers, policy-advisors, practitioners and the interested public, the book furthermore: • discusses the political, legal, economic and institutional dimensions of the issue• highlights normative questions central to the discourse • provides a focus on climate risks and climate risk management. • presents salient case studies from around the world.

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Funky, fascinating...and freaky! These are just some of the words that describe the captivating and sometimes strange world of scientific discovery. Worms with two heads, fruit that conducts electricity, and miniature brains that grow in petri dishes are a few of the totally weird topics in this volume, which demonstrates to readers just how bizarre science can be. While examining scientific peculiarities, readers will come to understand more about the theories and principles behind them. Engaging images, fact boxes, and sidebars reinforce the concepts, which are closely connected to the elementary science curriculum.