State Government Research Checklist

Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

June and Dec. issues contain listings of periodicals.

Sharing knowledge is what drives scientific progress - each new advance or innovation in biomedical research builds on previous observations. However, for experimental findings to be broadly accepted as credible by the scientific community, they must be verified by other researchers. An essential step is for researchers to report their findings in a manner that is understandable to others in the scientific community and provide sufficient information for others to validate the original results and build on them. In recent years, concern has been growing over a number of studies that have failed to replicate previous results and evidence from larger meta-analyses, which have pointed to the lack of reproducibility in biomedical research. On September 25 and 26, 2019, the National Academies of Science, Engineering, and Medicine hosted a public workshop in Washington, DC, to discuss the current state of transparency in the reporting of preclinical biomedical research and to explore opportunities for harmonizing reporting guidelines across journals and funding agencies. Convened jointly by the Forum on Drug Discovery, Development, and Translation; the Forum on Neuroscience and Nervous System Disorders; the National Cancer Policy Forum; and the Roundtable on Genomics and Precision Health, the workshop primarily focused on transparent reporting in preclinical research, but also considered lessons learned and best practices from clinical research reporting. This publication summarizes the presentation and discussion of the workshop.

Since the publication of the first edition in 1985, Missouri Government and Politics has been widely acclaimed as an outstanding text. This revised and enlarged edition updates all of the chapters to reflect the changes that have occurred in the state's government during the last decade. Five new chapters have been added on topics previously unaddressed: economic development, energy, and the environment; state policy making in higher education; funding for education in the 1990s; the statewide elected executive officials; and the types of law in Missouri. The twenty-six chapters are grouped into four main categories: "The Context of Missouri Politics," "State Governmental Framework," "Policies and Policy Making in Missouri," and "Local Government and Politics in Missouri." Helpful additions to the basic text include more than fifty tables and figures, a glossary giving clear definitions of many governmental terms, and a bibliography on Missouri politics and government. The authors have become experts about Missouri by serving as teachers and researchers in Missouri colleges and universities, as candidates and workers in Missouri political campaigns, and as officeholders and public administrators in Missouri state government. Their collective experience in Missouri politics ensures that this new edition provides the most thorough and comprehensive overview of the structure and inner workings of Missouri's political system.