Stress Response In Microbiology

To survive adverse and fluctuating conditions, microorganisms possess mechanisms to recognise diverse environmental changes and mount an appropriate response. Microorganisms frequently react simultaneously to a wide variety of stresses and the various stress response systems interact with each other by a complex of global regulatory networks. Stress response systems can play an important role in the virulence of pathogenic organisms. In this book, expert authors from around the world summarise the current knowledge on microbial stress response and comprehensively review the recent findings that have greatly advanced the understanding of stress response systems. Each chapter is devoted to a particular organism or group of organisms including Gram-negative bacteria, Streptococcus, Neisseria, Listeria monocytogenes, Bacillus cereus, Salmonella, Yersinia, Vibrio, Mycobacterium, mycoplasmas, yeast, Plasmodium falciparum, Toxoplasma gondii, Leishmania, Trypanosoma cruzi, Trypanosoma brucei and Entamoeba histolytica. In addition to providing an up-to-date review of current trends the authors also describe the challenges for future research and provide comprehensive reference sections. The volume represents a major collection of information and knowledge across a wide range of microorganisms and is essential reading for anyone with an interest in stress response. A highly recommended book for anyone interested in stress response, regulatory networks, environmental microbiology or the pathogenicity of microorganisms.

Gain new insight on utilizing bacterial stress responses to better combat bacterial infection with antibiotics and improve biotechnology. • Reviews the vast number of new findings that have greatly advanced the understanding of bacterial stress responses in the past 10 years. • Explores general regulatory principles, including the latest findings from genomics studies, including new research findings on both specific and general stress responses. • Details how stress responses affect the interactions between bacteria and host cells and covers bacterial stress responses in different niches and communities, with an emphasis on extreme environments.

Throughout the food processing chain and after ingestion by the host, food associated bacteria have to cope with a range of stress factors such as thermal and/or non-thermal inactivation treatments, refrigeration temperatures, freeze-drying, high osmolarity, acid pH in the stomach or presence of bile salts in the intestine, that threaten bacterial survival. The accompanying plethora of microbial response and adaptation phenomena elicited by these stresses has important implications for food technology and safety. Indeed, while resistance development of pathogenic and spoilage microorganisms may impose health risks for the consumer and impart great economic losses to food industries, reduced survival of probiotic bacteria may strongly compromise their claimed health benefit attributes. As a result, substantial research efforts have been devoted in the last decades to unravel the mechanisms underlying stress response and resistance development in food associated microorganisms in order to better predict and improve (i) the inactivation of foodborne pathogens and spoilage microorganisms on the one hand and (ii) the robustness and performance of beneficial microorganisms on the other. Moreover, the recent implementation of system-wide omics and (single-)cell biology approaches is greatly boosting our insights into the modes of action underlying microbial inactivation and survival. This Research Topic aims to provide an avenue for dissemination of recent advances within the field of microbial stress response and adaptation, with a particular focus not only on food spoilage and pathogenic microorganisms but also on beneficial microbes in foods.

The ability of pathogenic bacteria to adapt to various chemical, biochemical and physical conditions within the human host and their ability to respond to stresses generated in these environments is a central feature of infectious diseases and the outcome of bacterial infection. This book covers the key aspects of this rapidly developing field, including the generation of stresses by the host immune system, bacterial response to reactive chemicals, and adaptation to environmental conditions of anatomical niches such as the gut, mouth and urogenital tract. It also addresses the increasing impor.

Food-borne bacterial pathogens encounter a number of stressors during food processing and preservation. More and more pathogens are able to adapt their physiological properties and/or genetic expression to survive these stressors and pose a risk to food safety and public health. This book provides the reader with a comprehensive overview of common food processing-associated stressors (e.g., heat, cold, acid, osmosis, and oxidation) and deals with the molecular basis of the respective bacterial stress response mechanisms (e.g., viable but nonculturable state, biofilm formation, sporulation, and cross-protection response). Additionally, various chapters cover the response mechanisms of foodborne pathogens to emerging nonthermal sterilisation technologies such as ultrasound, high-pressure processing, pulsed electric fields, ultraviolet light, irradiation and phytochemicals. Through this book we also learn about future prospects for the efficient control of stress adaption in foodborne pathogens to ensure maximum consumer safety. This book offers a valuable resource for researchers, graduate students, food process engineers and product developers in the fields of food science and microbiology.

Beginning with the basics of lactic acid bacteria and stress response, then working into specific fields of research and current developments, Stress Responses of Lactic Acid Bacteria will serve as an essential guidebook to researchers in the field, industry professionals, and advanced students in the area. The exploration of stress responses in lactic acid bacteria began in the early 90s and revealed the differences that exist between LAB and the classical model microorganisms. A considerable amount of work has been performed on the main genera / species of LAB regarding the genes implicated and their actual role and regulation, and the mechanisms of stress resistance have also been elucidated. Recent genome and transcriptome analyses complement the proteome and genetic information available today and shed a new light on the perception of and the responses to stress by lactic acid bacteria.

A critical factor for bacterial survival in any environment is the ability to sense and respond appropriately to insults that cause stress to the cell, threatening its survival. Most of these stressors first affect the outer surface of the bacterial cell, are sensed in some way, and defense measures are enacted in response. If the bacteria successfully respond to an encountered stress, they survive and multiply. If they are unsuccessful or inefficient in their response, it can result in death. Efficiently responding to factors that induce stress is especially important for bacteria that inhabit environments that are constantly changing, or for those that inhabit more than one biological niche. In addition, bacterial species that associate with humans and other organisms must be able to overcome stresses that are produced by the host immune response in order to colonize and cause disease. The wide variety of stressors encountered by bacteria has resulted in countless strategies that are used by pathogens to overcome these insults, which we continue to identify. Clearly, a better understanding of these stress response mechanisms may be useful for developing new strategies to combat bacteria that cause certain infectious diseases. This Research Topic aims to highlight our increasing understanding of mechanisms by which bacteria sense and respond to stresses encountered in the host or other environments. Examples of stress response mechanisms of interest include, but are not limited to those that respond to antimicrobials, host immune responses, or environmental changes.

In this book, expert authors from around the world summarise the current knowledge on microbial stress response and comprehensively review the recent findings that have greatly advanced the understanding of stress response systems. Each chapter is devoted to a particular organism or group of organisms including Gram-negative bacteria, Streptococcus, Neisseria, Listeria monocytogenes, Bacillus cereus, Salmonella, Yersinia, Vibrio, Mycobacterium, mycoplasmas, yeast, Plasmodium falciparum, Toxoplasma gondii, Leishmania, Trypanosoma cruzi, Trypanosoma brucei and Entamoeba histolytica. In addition t.