Studies On Graphene Based Nanomaterials For Biomedical Applications

This thesis presents various applications of graphene-based nanomaterials, especially in biomedicine. Graphene and its derivatives have gained enormous attention from scientists in all fields of study due to many unprecedented properties. The initial scientific attention was focused on the development of transparent flexible electrodes by exploiting two-dimensional graphene film’s extraordinary electrical and physical properties. Recently, given an increasing evidence of dispersed graphene-based nanomaterials’ biocompatibility, researchers have endeavored to employ these materials in other studies relevant to biomedical technologies. In this respect, the thesis provides a comprehensive review on the synthesis, toxicity, and a few of the key biomedical applications in the first chapter. The following chapter discusses the use of a graphene film as a novel catalyst to oxidatively destroy phenols, which are known to be potentially mutagenic and carcinogenic. Finally, and most importantly, the last chapter introduces the therapeutic role of graphene quantum dots, the smallest graphene-based nanomaterials, for Parkinson’s disease. The results are promising for the use of graphene quantum dots as the basis of future clinical drug candidates for neurodegenerative disorders. ​

This book explains the fundamental characteristics and biofunctionality of graphene-based nanomaterials and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the chemical composition and physical properties of graphene and its derivatives as well as their potential toxicity and biosafety. Detailed attention is then devoted to the potential of multifunctional graphene-based nanomaterials (MFGNs) to direct the differentiation of stem cells into specific lineages and induce tissue regeneration. Here, individual chapters address the application of MFGNs for the purposes of neurogenesis, osteo- and chrondrogenesis, myogenesis, and wound healing. Subsequent sections focus on the capability of MFGNs as agents for drug delivery, bioimaging, theranostics, and therapeutics as well as their effectiveness as biomimetic platforms for nanobiosensors, biochips, medical devices, and dental applications. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel MFGN-incorporated composite materials and develop functional devices based on them.

The book presents a comprehensive overview of the historical, current, and prospective application realms of nanobiotechnological research pertaining to graphene, a carbon-based nanomaterial, and its diverse forms in the fields of food and agriculture, as well as health sciences and technology. Young nanotechnologists and businesses will have access to nanobioanalytical methods. Given the present circumstances, it is crucial to underscore the potential ramifications that diverse forms of graphene nanomaterials could have on the food sector, agricultural methodologies, and healthcare. This book presents an analysis of the potential advantages of graphene-based nanomaterials over traditional materials in the food, agriculture, and health care sectors. This book employs case studies, academic and theoretical literature, technology transfer, innovation, economics, and policy management to underscore the intricate issues associated with graphene nanomaterials. The pioneering text Graphene-Based Nanomaterials: Application in Food, Agriculture, and Healthcare has the potential to serve as a valuable resource for interdisciplinary researchers, academics, practitioners, policymakers, and professionals operating within the fields of science, technology, engineering, innovation, management, and economics. Features · Discusses the different aspects of graphene as a two-dimensional material and its underlying unique physicochemical properties, synthesis methods, and protocols. · Considers the implications of graphene in the food sciences and its different spoilage detection mechanisms have been encompassed in the book. · Explores graphene nanomaterials' medical and biomedical uses. With examples, the unique and tailor-made material's uses and prospects in health sciences, pharmaceutics, and biomedical research are highlighted. · Elaborates on graphene's applications in agriculture and briefs the potential of biocompatible planar conductive nanoscale materials to boost agri-product production, crop development, and crop-infection surveillance.

Biomedical Applications of Graphene and 2D Nanomaterials provides a much-needed reference on the biomedical applications of 2D nanomaterials, as well as theoretical knowledge on their structure, physicochemical properties and biomedical applications. Chapters are dedicated to growth areas, such as size and shape-dependent chemical and physical properties and applications, such as in diagnostic and therapeutic products. The book also discusses the concept, development and preclinical studies of 2D nanomaterials-based biomedical tools, such as biosensors, artificial organs and photomedicine. Case studies and reports form the core of the book, making it an ideal resource on potential applications in biomedical science and engineering. This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications. Presents advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials Provides state-of-the-art biomedical applications for 2D nanomaterials, including graphene and boron nitride Includes key information from a broad selection of subject areas for researchers in both materials, engineering and medicine

This book highlights the evolution of, and novel challenges currently facing, nanomaterials science, nanoengineering, and nanotechnology, and their applications and development in the biological and biomedical fields. It details different nanoscale and nanostructured materials syntheses, processing, characterization, and applications, and considers improvements that can be made in nanostructured materials with their different biomedical applications. The book also briefly covers the state of the art of different nanomaterials design, synthesis, fabrication and their potential biomedical applications. It will be particularly useful for reading and research purposes, especially for science and engineering students, academics, and industrial researchers.

Graphene Bioelectronics covers the expending field of graphene biomaterials, a wide span of biotechnological breakthroughs, opportunities, possibilities and challenges. It is the first book that focuses entirely on graphene bioelectronics, covering the miniaturization of bioelectrode materials, bioelectrode interfaces, high-throughput biosensing platforms, and systemic approaches for the development of electrochemical biosensors and bioelectronics for biomedical and energy applications. The book also showcases key applications, including advanced security, forensics and environmental monitoring. Thus, the evolution of these scientific areas demands innovations in crosscutting disciplines, starting from fabrication to application. This book is an important reference resource for researchers and technologists in graphene bioelectronics—particularly those working in the area of harvest energy biotechnology—employing state-of-the-art bioelectrode materials techniques. Offers a comprehensive overview of state-of-art research on graphene bioelectronics and their potential applications Provides innovative fabrication strategies and utilization methodologies, which are frequently adopted in the graphene bioelectronics community Shows how graphene can be used to make more effective energy harvesting devices

This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly. With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.

Carbon nanomaterials have a unique place in Nanoscience owing to their exceptional electrical, thermal, chemical and mechanical properties and have found application in areas as diverse as composite materials, energy storage and conversion, sensors, drug delivery, field emission devices and nano-scale electronic components. Conjugated carbon nanomaterial covers the areas of carbon nanotubes, fullerenes and graphene. Graphene is the newest of the carbon nanomaterials and promises to be a very active field. Already since its isolation in 2004 it has grabbed the attention of the chemistry, materials and physics communities. It promises to rival carbon nanotubes in terms of properties and potential applications with the number of publications rising from ca. 130 in 2005 to ca. 2,800 in 2010. In this short book Sekhar Ray gives an overview on graphene and graphene-oxide with a strong focus on applications. Structured in three chapters, one on graphene, one on graphene-oxide and one on graphene based nanoparticles his resource describes in each chapter the preparation (including synthesis and functionalization) and material properties before detailing a whole range of applications. Ray finishes each chapter with information on remaining challenges and perspectives. Written by an expert in the field who, during his last 17 years of research, has published more than 80 peer reviewed articles in recognized international journals Gives full-chapter overviews on Graphene, Graphene-Oxide, and Graphene based nanoparticles Focusses on applications