Super Bugs

International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?

Kids who like insects, superheroes, and good fighting evil will love the Super Bugs! The Super Bugs help insects when they are in danger!"Antennae up, eyes down.Buzzing all around the town.Super Bugs, Super Bugs, mighty, mightySuper Bugs!"These heroic insects are ready to fly in and lend a helping hand or wing! The Super Bugs spend all day doing good, and when the day ends..."To the hideout -- cozy nest. Even heroes need to rest."Young insect enthusiasts will enjoy the fun facts for all nineteen insects in Super Bugs: ants, beetles, bumblebees, butterflies, caterpillars, cicadas, cockroaches, crickets, daddy longlegs, dragonflies, fireflies, fleas, grasshoppers, houseflies, mosquitoes, moths, spiders, stinkbugs, and termites.

Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.

Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.

Explains how superbugs came to be, what scientists are doing to fight them, and how you can protect yourself against these microscopic menaces.

An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.

Inner jacket folds out to reveal a super-size beetle poster.

Come face to face with the most incredible insects on Earth, where you'll experience the microscopic world of bugs in mind-blowing depth and detail. Super Bug Encyclopedia showcases a huge variety of these tiny creatures at close range, making them millions of times bigger than their true size to give you the complete picture. From ants to wasps and centipedes to spiders, experience amazing anatomy and athleticism and find out who comes out on top for strength and speed. You'll meet the hawkmoth with the longest tongue of any insect and discover the velvet worm that squirts sticky slime to snare prey. Stand clear as the African bombardier beetle blasts out a sizzling hot chemical attack and race alongside the glorious green tiger beetle that lives life in the fast lane. This stunning visual feast incorporates jaw-dropping photography, at-a-glance facts, amazing statistics, dashboard-style profiles, and expert information to give you an unprecedented insight into the complex life of creepy crawlies. Did you know bugs are the most successful creatures on our planet? Or that insects took flight 150 million years before the first bird? Find out all this and much, much more inside as you become the ultimate bug hunter.