The Basic Science Of Oncology

This concise text examines cancer causation and biology as well as the biology underlying cancer treatment. Thoroughly updated and reorganized with five new chapters, the Fourth Edition emphasizes new development in molecular biology, hormone therapy, and the pharmacology of anti-cancer drugs. Features updated coverage of the basic science of radiotherapy and experimental radiation in addition to expansive coverage of new drugs developments.

NOW IN FULL COLOR! Discover the science of cancer--with this newly revised, essential introduction to cancer biology and genetics Here in one well-organized, reader-friendly volume, you'll find everything you must know about the biology underlying cancer and its treatment, supported by the latest peer-reviewed research. Written by preeminent oncology researchers and clinicians, the book highlights the full range of important oncology topics and takes you through the biological basis of current and future biological therapy as well as more traditional approaches to cancer treatment. Presented in full color, the Fifth Edition of The Basic Science of Oncology is thoroughly updated and refreshed to reflect the latest critical thinking in oncology. For graduate students, oncologists, residents, and fellows, there can be no more useful guide to the bedrock science and practice of oncology than this all-in-one reference. FEATURES: The most current, evidence-based oncology primer--one that encapsulates the science of cancer causation, cancer biology, and cancer therapy Key insights into molecular and genetic aspects of cancer familiarize you with cancer biology as applied to prognosis and personalized cancer medicine In-depth focus on the discovery, evaluation, and biology of anti-cancer drugs, immunotherapy, and molecularly-targeted agents Up-to-date coverage of the basic science of radiation therapy Specific chapters/sections on intratumor heterogeneity as it relates to potential new treatment strategies--including tumor microenvironment and metabolism, tumor stem cells, and genomic/proteomic heterogeneity NEW! Chapter Essentials synthesize chapter content in a convenient list NEW! Color diagrams and schematics summarize important data

Complete coverage of the basis of cancer and molecular biology – from globally recognized experts The Basic Science of Oncology is an accessible and thorough introduction to cancer causation, cancer biology, and the biology underlying cancer treatment. You’ll find everything you need to know about the latest critical thinking in oncology, as well ready to apply information about state-of-the-art science and therapeutic applications. Written by leading oncology researchers and clinicians, this is an essential resource for health professionals, students, advanced undergraduates and graduates in biological sciences, and clinicians needing an understanding of cancer cells. Presented in full-color, The Basic Science of Oncology reflects the latest research and developments in the field. Features NEW chapters: Epigenetics and Principles of Genome Regulation and Targeted Cancer Diagnosis and Treatment Thoroughly revised content, with expanded coverage of key topics such as immune system and immunotherapy, tumor growth and metabolism, vaccine development, methods of molecular analysis, tumor environment, and more The most current, evidence-based oncology primer—one that encapsulates the science of cancer causation, cancer biology, and cancer therapy Key insights into molecular and genetic aspects of cancer familiarize you with cancer biology as applied to prognosis and personalized cancer medicine In-depth focus on the discovery, evaluation, and biology of anti-cancer drugs, immunotherapy, and molecularly-targeted agents Up-to-date coverage of the basic science of radiation therapy

Basic Science of Oncology, 5e is an engaging state-of-art review of cancer causation, cancer biology, and the biology underlying cancer treatment. The fifth edition features critical updates in all areas of the fast-moving field of cancer care

“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.

"Basics of Oncology" provides an easily understood and general overview of the basic medical, scientific and clinical aspects of cancer. Causes, pathology, clinical features, diagnostic investigations, treatments and outcomes are all carefully explained and discussed, both for cancers in general and for the common cancers in individual countries. The reader will thereby be provided with an understanding of how and why people develop cancer, how the body reacts to cancer, what can be done to prevent the disease, and how the various cancers are best diagnosed and treated. The book will serve as a sound basis for the more detailed or specific studies that may be needed in different areas of practice and in different countries. It will be invaluable for students of medicine, nurse oncologists, students of medical sciences and other health professionals in all parts of the world.

This volume of our Orthopaedic Surgery Essentials Series presents all the information residents need during orthopaedic oncology rotations and the essential basic science needed for board preparation, clinical practice, and orthopaedic research, including molecular and cellular biology, growth and development, the genetic basis of musculoskeletal disorders, biomaterials and biologic response to orthopaedic implants, and neoplastic disorders. The book can easily be read cover to cover during a rotation or used for rapid review before boards or quick reference in clinical practice. The user-friendly, visually stimulating format features numerous tables and ample illustrations, including color plates showing tumor histopathology.

Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer – From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.