The Biology Of Senescence
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The Biology of Senescence
Author | : Alex Comfort |
Publsiher | : Elsevier Publishing Company |
Total Pages | : 432 |
Release | : 1979 |
Genre | : Science |
ISBN | : UOM:39015003805994 |
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The Biology of Senescence
Author | : Bernard Swynghedauw |
Publsiher | : Springer |
Total Pages | : 121 |
Release | : 2019-06-06 |
Genre | : Medical |
ISBN | : 9783030151119 |
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This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for “treating” it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related “chronic non-transmissible diseases”), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to “treat” or “prevent” the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
The Biology of Senescence
Author | : Bernard Swynghedauw |
Publsiher | : Unknown |
Total Pages | : 121 |
Release | : 2019 |
Genre | : Family medicine |
ISBN | : 3030151123 |
Download The Biology of Senescence Book in PDF, Epub and Kindle
This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for "treating" it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related "chronic non-transmissible diseases"), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to "treat" or "prevent" the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
Ageing the Biology of Senescence
Author | : Alex Comfort |
Publsiher | : Unknown |
Total Pages | : 392 |
Release | : 1964 |
Genre | : Aging |
ISBN | : UOM:39015037514117 |
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The Biology of Aging
Author | : John A. Behnke |
Publsiher | : Springer Science & Business Media |
Total Pages | : 388 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9781461339946 |
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Egocentricity is characteristically human. It is natural for our prime in terest to be ourselves and for one of our major concerns to be what affects us personally. Aging and death - universal and inevitable have always been of compelling concern. Mystical explanations were invented when scientific answers were lacking. and gross physiologi As scientific knowledge developed, anatomy cal processes were explained, and the roles of the endocrine glands were revealed. Since the sex hormones obviously lose some of their potency with age, it was logical to assume that they played the major role in declining general well-being. The puzzle of aging would now be solved. The Ponce de Leon quest would soon be fulfilled. Pseudoscientists and quacks rushed in where most scientists feared to tread. By the time the glowing promises of perpetual youth through gland transplants and injections had proved illusory, serious study of the aging process had been set back for years. The field had lost "respect ability," and most capable scientists shunned it. Those who did con tinue to seek answers to its tough questions deserve special recognition.
Longevity Senescence and the Genome
Author | : Caleb E. Finch |
Publsiher | : University of Chicago Press |
Total Pages | : 948 |
Release | : 1994-05-16 |
Genre | : Health & Fitness |
ISBN | : 0226248895 |
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Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.
Times Cells and Aging
Author | : Bernard Strihler |
Publsiher | : Academic Press |
Total Pages | : 510 |
Release | : 1977-01-28 |
Genre | : Science |
ISBN | : UOM:39015004326321 |
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Time, Cells, and Aging, 2nd Edition presents the mechanics of cell function and the relevant implications of the molecular-genetic view to the aging phenomena. This book explores the biology of the aging process. Comprised of 11 chapters, this edition starts with an overview of the causes and mechanisms underlying the gradual deterioration of structure and function characteristics of aging. This text then examines the two aspects of the behavior of man, including the reasoned conscious behavior and the greater dependence on reaction patterns predicted on the successful responses of the past. Other chapters explore the relationship between aging and mortality rate in animals, which is a result of an organism's deceasing ability to function optimally in carrying out his vital functions. The final chapter deals with the implementation of a research plan relevant to understanding the primary mechanisms of the aging process. This book is a valuable resource for gerontologists, biologists, and molecular biologists.
The Evolution of Senescence in the Tree of Life
Author | : Richard P. Shefferson,Owen R. Jones,Roberto Salguero-Gómez |
Publsiher | : Cambridge University Press |
Total Pages | : 445 |
Release | : 2017-02-23 |
Genre | : Science |
ISBN | : 9781107078505 |
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Top researchers in the field introduce interdisciplinary perspectives on senescence, presenting new insights and cutting-edge research.