The Brain And Pain

Pain is an inevitable part of existence, but severe debilitating or chronic pain is a pathological condition that diminishes the quality of life. The Brain and Pain explores the present and future of pain management, providing a comprehensive understanding based on the latest discoveries from many branches of neuroscience. Richard Ambron—the former director of a neuroscience lab that conducted leading research in this field—explains the science of how and why we feel pain. He describes how the nervous system and brain process information that leads to the experience of pain, detailing the cellular and molecular functions that are responsible for the initial perceptions of an injury. He discusses how pharmacological agents such as opiates affect the duration and intensity of pain. Ambron examines new evidence showing that discrete circuits in the brain modulate the experience of pain in response to a placebo, fear, anxiety, belief, or other circumstances, as well as how pain can be relieved by activating these circuits using mindfulness training and other nonpharmacological treatments. The book also evaluates the prospects of procedures such as deep brain stimulation and optogenetics. Current and thorough, The Brain and Pain will be invaluable for a range of people seeking to understand their options for treatment as well as students in neuroscience and medicine.

It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients Clinical data from pain patients’ brains Advances in noninvasive brain imaging for pain patients Combining theoretical and empirical approaches to the analysis of pain-related brain function Manipulation of brain function in animal models Emerging neurotechnology principles for pain diagnostics and therapeutics

Explains how physical and emotional pain are stored in the brain, and what causes pain to persist after the injury or trauma that initially triggered it. The book describes five core sensory- emotional skills for reversing the brain activity that maintains pain.

Pain and the Conscious Brain brings together more than 30 international leaders from multiple fields to link the complex concept of pain to the equally complex notion of consciousness. Offering a clear, cutting-edge understanding of the brain mechanisms that generate the conscious experience of pain, this book scientifically addresses the difficult and chronic pains that often have no known physical cause and can defy comprehension in terms of current pain theories. Numerous tables, full-color figures, and up-to-date references highlight expert coverage of today’s gradual paradigm shift from peripheral receptors to the intricacy of the brain and the experience of the self.

One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on: Nociceptor sensitization Muscle nociceptors and metabolite detection Visceral afferents in disease Innovative rodent model for bone cancer pain Highly specific receptor cloning Modular molecular mechanisms relevant to painful neuropathies This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.

Dr. John E. Sarno's groundbreaking research on TMS (Tension Myoneural Syndrome) reveals how stress and other psychological factors can cause back pain-and how you can be pain free without drugs, exercise, or surgery. Dr. Sarno's program has helped thousands of patients find relief from chronic back conditions. In this New York Times bestseller, Dr. Sarno teaches you how to identify stress and other psychological factors that cause back pain and demonstrates how to heal yourself--without drugs, surgery or exercise. Find out: Why self-motivated and successful people are prone to Tension Myoneural Syndrome (TMS) How anxiety and repressed anger trigger muscle spasms How people condition themselves to accept back pain as inevitable With case histories and the results of in-depth mind-body research, Dr. Sarno reveals how you can recognize the emotional roots of your TMS and sever the connections between mental and physical pain...and start recovering from back pain today.

Think Away Your Pain presents a revolutionary approach to relieve suffering and eliminate chronic pain. In this user-friendly clearly written book, you will learn how chronic pain becomes a condition of the brain as much as the body. Think Away Your Pain shows you how to use the immense power of your thoughts and beliefs to literally change the neural circuitry of your brain.

This guide to harnessing the power of the brain to resolve chronic pain includes a variety of simple attention exercises and a 65-minute guided audio program For four decades, Dr. Les Fehmi has been a leader in brainwave biofeedback (also called neurofeedback), training individuals how to balance and regulate their brainwave patterns to improve mental, emotional, and physical health. Dissolving Pain is based on the premise that although pain is perceived to exist in a particular part of the body, pain in fact resides in the brain. Drawing on existing scientific research and on decades of clinical experience, Dr. Fehmi offers brain-training exercises that quiet the pain signal in the brain. The exercises involve altering the way we pay attention to pain, cultivating what Fehmi calls Open-Focus Attention: a relaxed form of awareness that changes the neural blood flow and increases alpha brainwave activity (associated with reduced stress and beneficial hormonal changes). These exercises are effective in the treatment of many forms of pain including back, shoulder, neck, and joint pain; headaches; muscle pain and tension; and pain from traumatic injury. Included with the book is a link to a 65-minute downloadable audio program in which Dr. Fehmi guides listeners through the fundamental Dissolving Pain exercises. To learn more, visit openfocus.com.