The Clinical Use Of Recombinant Human Erythropoietin A Report Of A Symposium

Drugs in Sport is the most comprehensive and accurate text on the emotive, complex and critical subject of performance enhancement and doping within sport. Thoroughly updated in light of the latest World Anti-Doping Code and taking into account the latest regulations, procedures and landmark cases, this 8th edition explores the science behind drug use in sport, as well as its ethical, social, political and administrative context. Introducing an increased focus on athletes with specific needs and on corrupt doping practices, the book covers key topics including: - an evaluation of the prevalence of doping in sport; - the latest doping control regulations stipulated by the World Anti-Doping Agency (WADA); - the science and side effects of each major class of drug used in sport; - cutting-edge issues such as drug use by transgender athletes; - medical and anti-doping considerations for athletes with an impairment; - governance and corruption in sport including institutionalised doping; - issues surrounding sport nutrition and supplement use in sport; - medical and pharmaceutical services at major sporting events. Accessibly written, and supported throughout with illustrative case studies and data, Drugs in Sport provides a crucial and objective resource for students and researchers, athletes, sports scientists, coaches and athlete-support staff, journalists, sports administrators and policymakers, alike.

The subject of this volume is to review chemical agents which affect blood and blood-forming organs. Significant ad- vances made over the past several years in the purification of several hematopoietic growth factors, such as erythro- poietin and colony stimulating factor; the availability of several other growth factors, such as the interleukins which are important in regulating the production of red blood cells, leukocytes, megakaryocytes and platelets are discus- sed. Numerous toxic chemical substances are being produced in our environment which people are exposed todaily causing a suppression of erythropoiesis, myelopoiesis and megakaryo- cytopoiesis. Attempts to evaluate both the therapeutic role of some of the newer growth factors, such as erythropoietin in the anemia of end stage disease, as well as colony stimu- lating factors in somehematopoietic abnormalities are also covered in this volume. In addition, numerous chemical fac- tors in our environment which suppress major hematopoietic lineages stimulated by erythropoietin, macrophage colony stimulating factor, granulocyte colony stimulating factor, interleukin 1-alpha, 1-beta, 2,3,4,5,6, and 7 are also in- cluded. In addition, chapters on the use of erythropoietin in the treatment of anemia of end stage renal disease can provide the practicing hematologist and nephrologist with updated information on the use of erythropoietin for this disease. The book includes chapters on the fundamental con- trol of hematopoiesis and other mechanisms of action of erythropoietin, and finally an up-to-date overview of the chemotherapy of leukemia. This book will prove useful to in- vestigators in the fields of pharmacology, physiology, nephrology, urology, hematology, pathology, endocrinology, biochemistry, and molecular and cell biology.

Confidently utilize the rapidly growing selection of pharmaceuticals used to treat small animals. Small Animal Pharmacology and Therapeutics, 2nd Edition helps you understand both the therapeutic uses of common pharmaceuticals and the pharmacology behind them, giving you all of the information you need to design and modify dosing regimens, identify factors that cause drugs to fail, and anticipate adverse drug reactions. Comprehensive approach emphasizes the use of drugs for prevention as well as treatment. Clear, consistent organization makes it easy to find the information you need when you need it. Dosage tables help you find essential pharmaceutical information at a glance. Pharmacogenetics chapter helps you understand how to use this emerging science to find the right dose for each patient, optimizing efficiency and minimizing toxicity. Routes of administration and sample pharmaceutical calculations provide fast, efficient access to comprehensive drug administration all in one inclusive resource. Multiple chapters on Antimicrobial Drugs and Antimicrobial Therapy highlight the impact of antimicrobial resistance on current practice.