The Developing Heart

Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...

​This heart anatomy book describes the cardiac development and cardiac anatomy in the development of the adult heart, and is illustrated by numerous images and examples. It contains 550 images of dissected embryo and adult hearts, obtained through the dissection and photography of 235 hearts. It has been designed to allow the rapid understanding of the key concepts and that everything should be clearly and graphically explained in one book. This is an atlas of cardiac development and anatomy of the human heart which distinguishes itself with the use of 550 images of embryonic, fetal and adult hearts and using text that is logical and concise. All the mentioned anatomical structures are shown with the use of suggestive dissection images to emphasize the details and the overall location. All the images have detailed comments, while clinical implications are suggested. The dissections of different hearts exemplify the variability of the cardiac structures. The electron and optical microscopy images are sharp and provide great fidelity. The arterial molds obtained using methyl methacrylate are illustrative and the pictures use suggestive angles. The dissections were made on human normal and pathological hearts of different ages, increasing the clinical utility of the material contained within.​

This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.

A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.

A version of the OpenStax text

Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.

"Development of the heart is a complex process and can lead to serious congenital disease if the process goes awry. This book provides a detailed description of the cell lineages involved in heart development and how their migration and morphogenesis are controlled. It also examines the genetic and environmental bases for congenital heart disease and how model systems are revealing more about the processes involved"--