The Edge Of Life

‘The world beyond the thought horizon is as vast as the universe, and probing it is the stuff of dreams, imaginative thinking and new technologies.’ The gap between rapid scientific progress and public understanding faces unprecedented challenges. Leading research scientist Mike Berridge explores this troubled ground from a rare vantage point. His descriptions of stunning new advances in human health are offset by hard questions about society’s ability to keep pace. This exploration brings us into contact with hotly contested public health issues, such as cancer treatment, sugar consumption, and water fluoridation. It is also a heartfelt plea to place robust and impartial science at the centre of our thinking for the future.

In this original and provocative book, Colin Dayan tackles head-on the inexhaustible world, at once tender and fierce, of dogs and humans. We follow the tracks of dogs in the bayous of Louisiana, the streets of Istanbul, and the humane societies of the United States, and in the memories and myths of the humans who love them. Dayan reorients our ethical and political assumptions through a trans-species engagement that risks as much as it promises. She makes a powerful case for questioning what we think of as our deepest-held beliefs and, with dogs in the lead, unsettles the dubious promises of liberal humanism. Moving seamlessly between memoir, case law, and film, Dayan takes politics and animal studies in a new direction—one that gives us glimpses of how we can think beyond ourselves and with other beings. Her unconventional perspective raises hard questions and renews what it means for any animal or human to live in the twenty-first century. Nothing less than a challenge for us to confront violence and suffering even in the privileged precincts of modernity, this searing and lyrical book calls for another way to think the world. Theoretically sophisticated yet aimed at a broad readership, With Dogs at the Edge of Life illuminates how dogs—and their struggles—take us beyond sentimentality and into a form of thought that can make a difference to our lives.

‘An intimate portrait of a woman who changed herself and Australia...Michelle Scott Tucker makes Elizabeth Macarthur step off the page.’ David Hunt , Author of Girt In 1788 a young gentlewoman raised in the vicarage of an English village married a handsome, haughty and penniless army officer. In any Austen novel that would be the end of the story, but for the real-life woman who became an Australian farming entrepreneur, it was just the beginning. John Macarthur took credit for establishing the Australian wool industry and would feature on the two-dollar note, but it was practical Elizabeth who managed their holdings—while dealing with the results of John’s manias: duels, quarrels, court cases, a military coup, long absences overseas, grandiose construction projects and, finally, his descent into certified insanity. Michelle Scott Tucker shines a light on an often-overlooked aspect of Australia’s history in this fascinating story of a remarkable woman. Michelle Scott Tucker owns and operates a management consulting company, and lives on a small farm in regional Victoria with her husband and children. Elizabeth Macarthur is her first book. ‘Tucker’s great achievement is to have scraped back the familiar historical material to uncover a fresh and compelling portrait of Elizabeth Macarthur in her own words and the words of those who knew her.’ Australian ‘In writing this lively, entertaining and profoundly empathetic biography, [Tucker] has also brought other colonial women out of the shaows and told their story too...There are not many biographies or histories of Australia that are unputdownable, but this one is. Highly recommended!’ ANZ LitLovers 'The triumphs and trials of Elizabeth Macarthur, a capable business woman and dedicated wife and mother, are given their due in this impressively researched biography.’ Brenda Niall ‘This carefully researched history is a highly interesting read that highlights the importance of women in the settlement of New South Wales.’ Otago Daily Times 'Finally, Elizabeth Macarthur steps out from the long shadow of her infamous, entrepreneurial husband. In Michelle Scott Tucker’s devoted hands, Elizabeth emerges as a canny businesswoman, charming diplomat, loving mother and indefatigable survivor. A fascinating, faithful portrait of a remarkable woman and the young, volatile colony she helped to build.’ Clare Wright ‘A nourishing, fascinating, and eye-opening read.’ Alpha Reader ‘Tucker expertly details the trials, tragedies and triumphs of the early settlement of NSW...This book is an important historical memoir documenting the incredible life of an Australian pioneer and her role as the matriarch of one of Australia’s first agricultural dynasties.’ Countryman ‘Elizabeth Macarthur: A Life at the Edge of the World is a great read. It crafts a compulsive story with good research, giving a convincing look into colonial New South Wales. It offers the pleasures of fine biography in tracing one person’s life in all its seasons, through its successes and failures, joys and miseries.’ NathanHobby blog ‘A stunning and intimate look at Elizabeth [Macarthur] and the family’s lives...Should be required reading in schools...An informative and learned look at colonial history.’ AU Review

"How well do I know myself?" When was the last time this question crossed your mind? As we live our lives, we fall into routines that often take us away from ourselves. We become distant from who we are. We often think we are immortal until we face events that present us with a reality-check. The moments that break this cycle make us pause and contemplate. Such moments of uncertainty are faced by patients and their families. It is in these moments, on the edge of life and death, when some of the most important insights about life, ourselves and others are realized with utmost clarity. Regardless of your age, the stories in this book will take you through a journey of such events experienced at patients' bedsides and prompt you to question yourself. There will be a tug of war between your mind and your heart with space provided for you to journal. What would you do in such situations? Are you prepared to face them? Your answers will take you on a roller coaster ride into a world that will help you grow closer to the person you think you are closest to - yourself.Proceeds from the sale of this book will go to support the alleviation of suffering of patients worldwide by funding Palliative Care Network (www.palliativecarenetwork.com) projects. Thank you for your support!

New York Times bestseller • Life on the Edge alters our understanding of our world's fundamental dynamics through the use of quantum mechanics. Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation? Using first-hand experience at the cutting edge of science, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge illustrates one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden describe the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge. Winner, Stephen Hawking Medal for Science Communication

‘This book is not just about life, but about discovery itself. It is about error and hubris, but also about wonder and the reach of science. And it is bookended with the ultimate question: How do we define the thing that defines us?’ – Siddhartha Mukherjee, author of The Gene We all assume we know what life is, but the more scientists learn about the living world – from protocells to brains, from zygotes to pandemic viruses – the harder they find it to locate the edges of life, where it begins and ends. What exactly does it mean to be alive? Is a virus alive? Is a foetus? Carl Zimmer investigates one of the biggest questions of all: What is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts – whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead. Life’s Edge is an utterly fascinating investigation by one of the most celebrated science writers of our time. Zimmer journeys through the strange experiments that have attempted to recreate life. Literally hundreds of definitions of what that should look like now exist, but none has yet emerged as an obvious winner. Lists of what living things have in common do not add up to a theory of life. It’s never clear why some items on the list are essential and others not. Coronaviruses have altered the course of history, and yet many scientists maintain they are not alive. Chemists are creating droplets that can swarm, sense their environment, and multiply – have they made life in the lab? Whether he is handling pythons in Alabama or searching for hibernating bats in the Adirondacks, Zimmer revels in astounding examples of life at its most bizarre. He tries his own hand at evolving life in a test tube with unnerving results. Charting the obsession with Dr Frankenstein’s monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.

A stunning portrait of community, identity, and sexuality by the critically acclaimed author of The Narrow Door When Paul Lisicky arrived in Provincetown in the early 1990s, he was leaving behind a history of family trauma to live in a place outside of time, known for its values of inclusion, acceptance, and art. In this idyllic haven, Lisicky searches for love and connection and comes into his own as he finds a sense of belonging. At the same time, the center of this community is consumed by the AIDS crisis, and the very structure of town life is being rewired out of necessity: What might this utopia look like during a time of dystopia? Later dramatizes a spectacular yet ravaged place and a unique era when more fully becoming one’s self collided with the realization that ongoingness couldn’t be taken for granted, and staying alive from moment to moment exacted absolute attention. Following the success of his acclaimed memoir, The Narrow Door, Lisicky fearlessly explores the body, queerness, love, illness, community, and belonging in this masterful, ingenious new book.

'It's a brilliant book... There are lessons in every paragraph... Get it now.' Chris Evans 'Wonderous and wild. I loved this book' James Nestor, bestselling author of Breath 'Moving, raw and unflinching' Julia Samuel, bestselling author of This Too Shall Pass 'Incredible storytelling' Dr Rangan Chatterjee, bestselling author of Feel Better in 5 ____________________________________________________________________________ How do you carry on when things go deadly wrong? When Dr Rahul Jandial operated on Karina, an eleven-year-old girl whose spinal cord was splitting in two, he had to make an impossible decision. He followed his head over his gut and Karina was left permanently paralysed, altering both patient and surgeon's lives for ever. This decision would haunt Rahul for decades, a constant reminder of the fine line between saving and damaging a life. As one of the world's leading brain surgeons, Rahul is the last hope for patients with extreme forms of cancer. In treating them, he has observed humanity at its most raw and most robust. He has journeyed to unimaginable extremes with them, guiding them through the darkest moments of their lives. Life on a Knife's Edge is Rahul's poetic and beautifully written account of the resilience, courage and belief he has witnessed in his patients, and the lessons about human nature he has learned from them. It is about the impossible choices he has to make, and the fateful consequences he is forced to live with. From challenging the ethics of surgical practices, to helping a patient with locked-in syndrome communicate her dying wish to her family, Rahul shares his extraordinary experiences, revealing the depths of a surgeon's psyche that is continuously pushed to its limits.