The Essential Guide To Magnetic Resonance

Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. Chapters written by world-leading experts in the field Fully illustrated Covers both proton and non-proton MRS Includes the background to novel MRS imaging approaches

Chapter 1 19F MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY IN VITRO APPLICATIONS (Authors: Zuzanna Bober, David Aebisher, Jacek Tabarkiewicz, and Dorota Bartusik-Aebisher) This chapter presents applications of Fluorine-19 Magnetic Resonance Imaging (19F MRI) in cancer research, tissue metabolomics, quantification of drug delivery, cellular tracking, tissue pH measurements and detection of 19F labeled cells. In this chapter, we review in vitro research applying 19F MRI and Magnetic Resonance Spectroscopy (MRS) to facilitate the synthesis, tracking and visualization of new fluorinated drug conjugates. Chapter 2 MAGNETIC RESONANCE IMAGING GUIDED PHOTODYNAMIC THERAPY (Authors: ?ukasz O?óg, Dorota Bartusik-Aebisher, Jacek Tabarkiewicz and David Aebisher) In this chapter, examples of current methods of magnetic resonance imaging (MRI) guided photodynamic therapy are presented. Recent development of MRI detectable nanoparticle constructs, magnetic resonance spectroscopy (MRS) sensors, gadolinium based photosensitizers and europium singlet oxygen probes are discussed. In addition, applications of Functional MRI using a blood oxygen dependent level (BOLD) MRI in monitoring photodynamic action is also addressed. Chapter 3 APPLICATION OF MRI TO THE STUDY OF PHARMACEUTICALS (Authors: Zuzanna Bober, David Aebisher, Piotr Tutka, and Dorota Bartusik-Aebisher) This chapter presents applications of MRI within the sphere of pharmacy; in particular, the use of MRI to track pharmaceuticals in vitro and in vivo noninvasively and monitoring their controlled-release is discussed. Chapter 4 FUNCTIONAL MRI - HOW DOES IT WORK? (Authors: Adrian Truszkiewicz, David Aebisher, Jacek Tabarkiewicz and Dorota Bartusik-Aebisher) This chapter presents research of functional MRI for noninvasive clinical brain imaging as it is applied to studies of autism, schizophrenia, epilepsy Alzheimer's disease, Parkinson's disease, traumatic brain injury and blood oxygenation-level dependent (BOLD) imaging of brain function.. The aim of this chapter is to provide an overview of the scope of fMRI as a diagnostic technique in neurology and in neurosurgery.

This book covers all aspects of low field MRI, describing its advantages, problems and prerequisites. Individual chapters are devoted to site planning, safety considerations, coils, imaging technique, image quality optimization, the imaging of different anatomic regions and likely future developments. The factors that must be borne in mind when selecting a low field system are clearly identified and detailed attention is paid to the applications for which such a system is adequate. The focus on high field systems has led to a situation where only a few systems with field strengths lower than 0.5 T survive. Some of these systems possess high field features such as multichannel coils and strong gradients; furthermore, sequence technology and image processing techniques taken from higher field strength systems have resulted in impressive imaging capabilities. While 1.5-T systems will probably continue to remain the standard, low field systems offer advantages such as the feasibility of dynamic joint examinations, improvement of T1 contrast, reduction of “missile effects” and decreased radiofrequency exposure. Low field strength MRI consequently has the potential to contribute to optimal patient management and given comparable image quality, its application may become an issue of patient safety. This book will be an invaluable asset to all who are involved in planning and/or running a low field strength MRI facility.

This is the second edition of a useful introductory book on a technique that has revolutionized neuroscience, specifically cognitive neuroscience. Functional magnetic resonance imaging (fMRI) has now become the standard tool for studying the brain systems involved in cognitive and emotional processing. It has also been a major factor in the consilience of the fields of neurobiology, cognitive psychology, social psychology, radiology, physics, mathematics, engineering, and even philosophy. Written and edited by a clinician-scientist in the field, this book remains an excellent user's guide to t

Magnetic Resonance Imaging in Tissue Engineering provides a unique overview of the field of non-invasive MRI assessment of tissue engineering and regenerative medicine Establish a dialogue between the tissue-engineering scientists and imaging experts and serves as a guide for tissue engineers and biomaterial developers alike Provides comprehensive details of magnetic resonance imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs Covers cell-based therapies, engineered cartilage, bone, meniscus, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by MRI Includes a chapter on oxygen imaging method that predominantly is used for assessing hypoxia in solid tumors for improving radiation therapy but has the ability to provide information on design strategies and cellular viability in tissue engineering regenerative medicine

Magnetic Resonance Procedures: Health Effects and Safety is the first authoritative text on MR procedures and its associated health and safety concerns written by noted radiologists, physicists, and scientists with expertise in the field. It contains both theoretical and practical information. This timely text discusses emergent issues related to MR imaging and concerns such as shielding, the safe use of contrast agents, and management of patients with claustrophobia, anxiety, and emotional stress. It also contains a sample pre-MR screening form; comprehensive safety information for over 700 implants, devices, and materials; a list of medical devices and products for interventional MR procedures; and a summary of peer-reviewed MR safety studies. In the wake of recent government demands for increased patient safety in hospitals, along with the rapidly expanding use of MRI, this book is particularly important. It is the definitive resource for information on the safety aspects of magnetic resonance procedures.

Covering the whole gamut of magnetic resonance imaging investigation this book provides non-radiologist clinicians with an understanding of the possibilities of this investigative technique.