The Liver Graft Before Transplantation

The Liver Graft Before Transplantation: Defining Outcome After Liver Transplantation provides a comprehensive overview of pre-transplant assessment and conditioning of liver grafts to guide the best strategy for successful transplantation for better outcomes for patients. Sections provide an overview of the history and indications for liver transplantations as well as coverage of current practices used in transplantation. Next donor and liver graft assessment are discussed with specific coverage of diseases that carry a risk of recurrence after liver transplantation, including hepatocellular carcinoma, NASH, primary biliary cholangitis, primary sclerosing cholangitis, and viral hepatitis. Finally, the impact of the use of suboptimal liver grafts and clues to make the right trade-of between benefit and risk are discussed. This is the perfect reference for clinicians who need a comprehensive, clinically relevant overview of pre-transplant assessment and conditioning of liver grafts and want to know what to expect in future years. Provides a comprehensive overview of pretransplant assessment and conditioning of liver grafts in one reference Provides the latest information in the rapidly evolving field of machine perfusion Includes expert opinions that help readers understand and anticipate issues to be addressed regarding the donor and the allograft before transplantation

Aimed at the trainee surgeon and experienced transplant surgeon, this compendium on split-liver grafting contains articles written by faculty members of the first International Course on Split-Liver Transplantation. It covers the main aspects of the field and is geared towards helping surgeons select the best surgical techniques as well as identifying the pitfalls. The text features detailed instructions on the various procedures as well as an overview of the area.

The field of liver transplantation has undergone tremendous change and continues to evolve at a fast pace. This book covers topics beyond standard care and discusses issues that are new and rapidly evolving in the field. These include innovative surgical methods to maximize the donor pool, non-surgical methods to expand the existing pool of additional donors, the changing face of liver rejection, and management of infections in the presence of new antivirals. This book is an interesting read for surgeons, hepatologists, and healthcare workers looking after patients who need or have had a liver transplant.

Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of liver transplantation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Access valuable pearls, pitfalls, and insights from Dr. Ronald Busuttil and Dr. Goran Klintmalm, two of the world's preeminent experts in liver surgery. Understand today's full range of transplantation techniques with complete step-by-step descriptions of each, and access the background information and management options for each hepatic disease entity. Take advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues. Overcome your toughest challenges in liver transplantation. Many new and thoroughly revised chapters include: Deceased Organ Donation after Cardiac and Brain Death; Liver Transplantation for Non-Alcoholic Steatohepatitis; Extended Criteria Donors; Best Techniques for Biliary and Vascular Reconstruction in Living Donor Transplantation; Small for Size Syndrome; Dual Grafts for Transplantation; Arterial Reconstructions-Pitfalls; Transition of Pediatric Patients to Adulthood; Immunosuppressive Biologic Agents; Long Term Toxicity of Immunosuppressive Therapy; Stem Cell and Liver Regeneration; and Extracorporeal Perfusion for Resuscitation of Marginal Grafts. Stay current in your field and optimize patient outcomes with coverage of the most recent advances in living donor transplantation, pediatric transplantation, and gene and stem cell therapy. Access the latest information on anti-rejection/immunosuppressive drugs, as well as comprehensive discussions of each drug or combination of drugs used to suppress immune system.

A major new reference work on Liver Transplantation written by the transplantation team of one of Asia's leading transplant centres with a foreword by Prof. Sir Roy Calne the liver transplantation pioneer and expert in immunosuppressant techniques. The book begins with an overview of transplantation team composition, international donor selection guidelines and donor management and goes on to discuss technique and management of DDLT, LDLT, Pediatric, Split, Domino and ABO-incompatible liver transplantation. Post-transplant management, immuno-suppression, follow-up, short and long-term complications and their outcomes, as well as recent advances in liver transplantation such as stem cell, hepatocyte and xenotransplantation, are also discussed.

Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical techniques to post-operative complications. Provides an in-depth understanding of all aspects of pediatric liver transplantation, ideal for pediatric hepatologists, pediatric transplant surgeons, and others on the pediatric transplant team. Covers all surgical techniques in detail, including split graft, living related, auxiliary, and domino. Discusses pediatric liver transplantation consideration for an increasing number of additional metabolic, hematologic and renal conditions; breakthroughs in grafting and stem cell therapy; and techniques and present role of hepatocyte transplantation. Uses a quick-reference templated format; each chapter includes an overview, pathophysiology, conventional management, controversies, and bulleted summary of key take-aways. Includes state-of-the-art mini-reviews based on updated references and author experience throughout the text. Features a full-color design with numerous algorithms, figures, and radiological and histopathological photos.

Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology The newly revised Second Edition of Liver Transplantation: Clinical Assessment and Management delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. Liver Transplantation provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list A discussion of care of the liver transplant recipient after the procedure in the short and long term Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, Liver Transplantation: Clinical Assessment and Management will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation.