The Physics Of Living Processes

This full-colour undergraduate textbook, based on a two semester course, presents the fundamentals of biological physics, introducing essential modern topics that include cells, polymers, polyelectrolytes, membranes, liquid crystals, phase transitions, self-assembly, photonics, fluid mechanics, motility, chemical kinetics, enzyme kinetics, systems biology, nerves, physiology, the senses, and the brain. The comprehensive coverage, featuring in-depth explanations of recent rapid developments, demonstrates this to be one of the most diverse of modern scientific disciplines. The Physics of Living Processes: A Mesoscopic Approach is comprised of five principal sections: • Building Blocks • Soft Condensed Matter Techniques in Biology • Experimental Techniques • Systems Biology • Spikes, Brains and the Senses The unique focus is predominantly on the mesoscale — structures on length scales between those of atoms and the macroscopic behaviour of whole organisms. The connections between molecules and their emergent biological phenomena provide a novel integrated perspective on biological physics, making this an important text across a variety of scientific disciplines including biophysics, physics, physical chemistry, chemical engineering and bioengineering. An extensive set of worked tutorial questions are included, which will equip the reader with a range of new physical tools to approach problems in the life sciences from medicine, pharmaceutical science and agriculture.

In this book, physics in its many aspects (thermodynamics, mechanics, electricity, fluid dynamics) is the guiding light on a fascinating journey through biological systems, providing ideas, examples and stimulating reflections for undergraduate physics, chemistry and life-science students, as well as for anyone interested in the frontiers between physics and biology. Rather than introducing a lot of new information, it encourages young students to use their recently acquired knowledge to start seeing the physics behind the biology. As an undergraduate textbook in introductory biophysics, it includes the necessary background and tools, including exercises and appendices, to form a progressive course. In this case, the chapters can be used in the order proposed, possibly split between two semesters. The book is also an absorbing read for researchers in the life sciences who wish to refresh or go deeper into the physics concepts gleaned in their early years of scientific training. Less physics-oriented readers might want to skip the first chapter, as well as all the "gray boxes" containing the more formal developments, and create their own á-la-carte menu of chapters.

This book presents the hotly debated question of whether quantum mechanics plays a non-trivial role in biology. In a timely way, it sets out a distinct quantum biology agenda. The burgeoning fields of nanotechnology, biotechnology, quantum technology, and quantum information processing are now strongly converging. The acronym BINS, for Bio-Info-Nano-Systems, has been coined to describe the synergetic interface of these several disciplines. The living cell is an information replicating and processing system that is replete with naturally-evolved nanomachines, which at some level require a quantum mechanical description. As quantum engineering and nanotechnology meet, increasing use will be made of biological structures, or hybrids of biological and fabricated systems, for producing novel devices for information storage and processing and other tasks. An understanding of these systems at a quantum mechanical level will be indispensable. Contents:Foreword (Sir R Penrose)Emergence and Complexity:A Quantum Origin of Life? (P C W Davies)Quantum Mechanics and Emergence (S Lloyd)Quantum Mechanisms in Biology:Quantum Coherence and the Search for the First Replicator (J Al-Khalili & J McFadden)Ultrafast Quantum Dynamics in Photosynthesis (A O Castro, F F Olsen, C F Lee & N F Johnson)Modelling Quantum Decoherence in Biomolecules (J Bothma, J Gilmore & R H McKenzie)The Biological Evidence:Molecular Evolution: A Role for Quantum Mechanics in the Dynamics of Molecular Machines that Read and Write DNA (A Goel)Memory Depends on the Cytoskeleton, but is it Quantum? (A Mershin & D V Nanopoulos)Quantum Metabolism and Allometric Scaling Relations in Biology (L Demetrius)Spectroscopy of the Genetic Code (J D Bashford & P D Jarvis)Towards Understanding the Origin of Genetic Languages (A D Patel)Artificial Quantum Life:Can Arbitrary Quantum Systems Undergo Self-Replication? (A K Pati & S L Braunstein)A Semi-Quantum Version of the Game of Life (A P Flitney & D Abbott)Evolutionary Stability in Quantum Games (A Iqbal & T Cheon)Quantum Transmemetic Intelligence (E W Piotrowski & J S≈adkowski)The Debate:Dreams versus Reality: Plenary Debate Session on Quantum Computing (For Panel: C M Caves, D Lidar, H Brandt, A R Hamilton, Against Panel: D K Ferry, J Gea-Banacloche, S M Bezrukov, L B Kish, Debate Chair: C R Doering, Transcript Editor: D Abbott)Plenary Debate: Quantum Effects in Biology: Trivial or Not? (For Panel: P C W Davies, S Hameroff, A Zeilinger, D Abbott, Against Panel: J Eisert, H M Wiseman, S M Bezrukov, H Frauenfelder, Debate Chair: J Gea-Banacloche, Transcript Editor: D Abbott)Nontrivial Quantum Effects in Biology: A Skeptical Physicist's View (H Wiseman & J Eisert)That's Life! — The Geometry of π Electron Clouds (S Hameroff) Readership: Graduate students and researchers in quantum physics, biophysics, nanosciences, quantum chemistry, mathematical biology and complexity theory, as well as philosophers of science. Keywords:Quantum Biology;Quantum Computation;Quantum Mechanics;Biophysics;Nanotechnology;Quantum Technology;Quantum Information Processing;Bio-Info-Nano-Systems (BINS);Emergence;Complexity;Complex Systems;Cellular Automata;Game Theory;Biomolecules;Photosynthesis;DNA;Genetic Code;DecoherenceKey Features:Is structured in a debate style, where contributors argue opposing positionsBrings together some of the finest minds and latest developments in the fieldIs entirely unique and there are no competing titles

The book of Erwin Schrödinger about life evokes a variety of basic questions concerning the understanding of life in terms of modern physics rather than biochemistry. Problems of organization and regulation of biological systems cannot be understood by revealing only the chemical processes of the living state. A group of reputable physicists — among them the followers of Heisenberg and Fröhlich — and biologists came to this same conclusion through several workshops on this topic. This book contains their contributions, written from different viewpoints of theoretical physics and modern biology. These articles are valuable not only for understanding life, but also for creating new and non-invasive diagnostic and therapeutic tools in medicine; they also contribute importantly to a deeper understanding of evolutionary processes, including the development of consciousness. Contents:All the Colors of a Rainbow in a Worm or: What is Life? (R Eichelbeck)Life — A Problem Inherent in the Research Context (F-T Gottwald)Truth and Knowledge (W Schommers)The Formative Powers of Developing Organisms (L V Beloussov)Communication — Basis of Life (L von Klitzing)On the Essence of Life — A Physical but Nonreductionistic Examination (H-J Fischbeck)Biophoton and the Quantum Vision of Life (R P Bajpai)Quantum Mechanics, Computability Theory and Life (J Swain)and other papers Readership: Scientists interested in the life sciences and related subjects. Keywords:

The Physics of living examines patterns that extend across the physical and psychological realms. Within its pages there is the opportunity to explore metaphors and through this exploration to examine life and career issues. Some of the topics addressed include life balance, energy transfer, identity development, burnout, quantum thinking, and hope, heroes and opportunity. This is a book about life and how to live in the world with wisdom, truth, and beauty.

This highly unusual book began as a serious inquiry into Schrödinger's question, “What is life?”, and as a celebration of life itself. It takes the reader on a voyage of discovery through many areas of contemporary physics, from non-equilibrium thermodynamics and quantum optics to liquid crystals and fractals, all necessary for illuminating the problem of life. In the process, the reader is treated to a rare and exquisite view of the organism, gaining novel insights not only into the physics, but also into “the poetry and meaning of being alive.” This much-enlarged third edition includes new findings on the central role of biological water in organizing living processes; it also completes the author's novel theory of the organism and its applications in ecology, physiology and brain science.

The living organisms and systems possess extraordinary properties of programmed development, differentiation, growth, response, movement, duplication of key molecules and in m any cases higher mental functions. But the organisms are physical objects so they must follow laws of physics yet they do not seem to obey them. Physicists cannot easily persuade themselves to accept this as finally true. Non-living objects are governed by these laws of physics and they can explain these properties. However, in the living systems too phenomena encountered like coupled non-linear interactions, manybody effects, cooperativity, coherence, phase transitions, reversible metastable states are being understood better with the aid of powerful theoretical and experimental techniques and hope is raised that these may let us understand the mysteriousness of life. Contributors to this volume are a small fraction of rapidly growing scientific opinion that these aspects of living bodies are to be expected in a hitherto inadequately suspected state of matter which is in the main directed by these physical properties pushed almost to limit. This state of matter, the living matter, deserves to be called The Living State. Mishra proposes that given hydrogenic orbitals, atoms showing easy hybridisability and multiple valances, molecules with low-lying electronic levels, "loosestructure", and a metabolic pump in thermodynamically open system, various fundamental properties of living state can emerge automatically. Structurally these are all known to be present.