Therapeutic Peptides And Proteins
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Therapeutic Peptides and Proteins
Author | : Ajay K. Banga |
Publsiher | : CRC Press |
Total Pages | : 375 |
Release | : 2005-09-14 |
Genre | : Medical |
ISBN | : 9781420039832 |
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Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up
Oral Delivery of Therapeutic Peptides and Proteins
Author | : Puneet Tyagi,Anand Subramony |
Publsiher | : Academic Press |
Total Pages | : 318 |
Release | : 2022-08-18 |
Genre | : Business & Economics |
ISBN | : 9780128210604 |
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Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource. Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems Examines developing technologies to improve future oral bioavailability Includes the in vitro and preclinical techniques needed for development
Therapeutic Peptides and Proteins
Author | : Ajay K. Banga |
Publsiher | : CRC Press |
Total Pages | : 400 |
Release | : 2015-04-23 |
Genre | : Medical |
ISBN | : 9781466566071 |
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There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic peptides and proteins are made available, it will be essential to formulate these drugs into safe, stable, and efficacious delivery systems. The pharmaceutical scientist involved in this effort needs to call upon the knowledge of several disciplines, such as pharmaceutics, medicinal chemistry, biochemistry, microbiology, and chemical engineering and needs to keep abreast with the latest research in the published literature. Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems, Third Edition provides a comprehensive overview of the field for scientists in industry and academia and for students, while also providing practical information on the challenges facing the formulation and delivery aspects of these unique macromolecules. In particular, the book: Explains how recombinant DNA techniques now allow us to produce therapeutic proteins in a commercially viable form Discusses the physical and chemical pathways of peptide and protein degradation Includes a detailed discussion of protein formulation and lyophilization Overviews the pharmacokinetic aspects of therapeutic peptides and proteins and discusses controlled delivery systems for parenteral administration, including microsphere formulations Discusses research progress on oral, transdermal, mucosal, and topical delivery systems discusses transdermal and topical delivery
Therapeutic Peptides and Proteins
Author | : Ajay K. Banga |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2023 |
Genre | : Electronic Book |
ISBN | : 0367268175 |
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Therapeutic Peptides and Proteins
Author | : Daniel R. Marshak,Teh-Yung Liu |
Publsiher | : Cold Spring Harbor Laboratory Press |
Total Pages | : 378 |
Release | : 1988 |
Genre | : Clinical trials |
ISBN | : UCAL:B4526768 |
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Proteins and Peptides
Author | : Randall J. Mrsny,Ann Daugherty |
Publsiher | : CRC Press |
Total Pages | : 288 |
Release | : 2009-10-19 |
Genre | : Medical |
ISBN | : 9781420078077 |
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Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is
Pharmaceutical Formulation Development of Peptides and Proteins
Author | : Lars Hovgaard,Sven Frokjaer,Marco van de Weert |
Publsiher | : CRC Press |
Total Pages | : 392 |
Release | : 2012-11-14 |
Genre | : Medical |
ISBN | : 9781439853894 |
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The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therap
Therapeutic Proteins and Peptides
Author | : Anonim |
Publsiher | : Academic Press |
Total Pages | : 408 |
Release | : 2018-04-18 |
Genre | : Science |
ISBN | : 9780128143414 |
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Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides to cure or manage symptoms of human diseases, with this release focusing on the Rational Design of Stable Liquid Formulations of Biopharmaceuticals, Formulation strategies for peptides, proteins and antibodies using nanotechnology, the Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles, Enzymatic approaches of protein-polymer conjugation, Chimeric small antibody fragments as a strategy to deliver therapeutic payloads, Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules, and more. Describes advances in the discovery and application of therapeutic proteins/peptides which allow better targeting to the site of treatment and cause fewer adverse effects when compared to chemical compounds used for disease treatment Targeted to a very wide audience of specialists, researchers and students Written by well-renown authorities in their field Includes a number of high quality illustrations, figures and tables