Thoracic Manifestations Of Rheumatic Disease An Issue Of Clinics In Chest Medicine

This issue of Clinics in Chest Medicine, edited by Dr. Danielle Antin-Ozerkis and Dr. Kristin Highland, is devoted to Thoracic Manifestations of Rheumatic Disease. Topics include: Scleroderma/Mixed Connective Tissue Disease (MCTD); Lupus and APLAS; Sjögren's Syndrome; Rheumatoid Arthritis; Polymyositis/Dermatomyositis; Small Vessel Vasculidities: GPA/MPA/EGPA; Ig4 Related Disease; Spondylarthropathies; Interstitial Pneumonia with Autoimmune Features; Immunosuppressive Therapy (toxicity monitoring, PJP prophylaxis, bone health, immunization, pulmonary drug toxicity); Transplantation (scleroderma, challenges with PRAs, reflux/dysmotility); Biomarkers, Antibodies, and Immunologic Evaluation of the Patient with Lung Disease; Radiology/Imaging of Pulmonary Manifestation of Connective Tissue Disease; and Pulmonary Pathology in Connective Tissue Disease.

The lungs are involved so frequently with rheumatologic problems. This issue will cover Radiology of lung disease in the rheumatic diseases, Histopathology of lung disease in the rheumatic diseases, Determining respiratory impairment, Lung disease in RA, Lung disease in scleroderma, and many more!

The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.

This issue brilliantly pairs a rheumatologist with a pulmonologist to explore each of the 14 article topics. Topics include autoantibody testing, ultility of bronchoalveolar lavage in autoimmune disease, and pulmonary manifestations of such conditions as scleroderma, rheumatoid arthritis, lupus erythematosus, Sjogren's Syndrome, Inflammatory Myopathies, and Relapsing Polychondritis. The pulmonary vasculitities are discussed, as is antiphospholipid antibody syndrome, ankylosing spondylitis, and the impact of osteoporosis on pulmonary fuction. Toxicity and monitoring of immunosuppressive therapy used in systemic autoimmune diseases is reviewed, as is lung transplantation in autoimmune diseases.

This issue of Clinics in Chest Medicine, edited by Dr. Denis O'Donnell and Dr. Alberto Neder, focuses on Clinical Respiratory Physiology. Articles include: The Pathophysiology of Obstructive Sleep Apnea; The Physiology of Mechanical Ventilation; Exercise Pathophysiology in Congestive Heart Failure; Control of Breathing; Breathing at Extremes; Exercise Pathophysiology in Interstitial Lung Disease; Importance of Physiology in Clinical Decision-Making in the ICU; Pulmonary Hypertension and Exercise; Physiologic Effects of Oxygen Supplementation During Exercise in COPD; Benefits and Pitfalls of DLCO measurements in Clinical Practice; Cardio-pulmonary Interactions in COPD-CHF; Exercise Physiology in COPD; Dyspnea of Unknown Origin: The Role of Exercise Testing; Assessment of Ventilatory Limitation During Exercise; Respiratory Muscle Assessment in Clinical Practice; Exertional Periodic Breathing in Heart Failure; and Strategies to Increase Physical Activity in Chronic Respiratory Diseases

This issue of Clinics in Chest Medicine, edited by Dr. Charles L. Daley and Dr. David Lewinsohn, focuses on Tuberculosis. Topics include: Epidemiology of Tuberculosis (TB) in the United States; Immunology of Tuberculosis; Tuberculosis and Biologics; Laboratory Diagnosis of Tuberculosis; Supranational Tuberculosis Reference Laboratories (a global approach); Treatment of Drug Susceptible Tuberculosis; Treatment of Drug-Resistant Tuberculosis; New Drugs for the Treatment of Tuberculosis; Diagnosis of Latent Tuberculosis: the Role of Interferon Gamma Release; Treatment of Latent Tuberculosis; Management of Children with Tuberculosis; Tuberculosis and HIV; The Future of Vaccines for Tuberculosis; and Preventing Transmission of M. Tuberculosis.

This issue of Clinics in Chest Medicine, edited by Dr. Serpil Erzurum and Dr. Sumita Khatri, is devoted to several key areas of interest related to understanding Asthma and its treatments. Topics covered in this issue include: Epidemiology of the Asthma Epidemic in the 21st Century; Classification of Asthma; Genetics and Epigenetics of Asthma; Pro-Inflammatory Pathways in the Pathogenesis of Asthma; Dysfunction of Bronchomotor Tone Pathways in Asthmatic Airway Smooth Muscle; Systematic Approach to Asthma of Varying Severity; Comorbidities and Non-allergic Triggers in Asthma Exacerbations and Severity; Microbiome in Mechanisms of Asthma; Diet and Metabolism in the Evolution of Asthma and Obesity; The Exposome of Asthma; Life Cycle of Childhood Asthma; Asthma over the Adult Lifecourse, considering Gender and Hormonal Influences; Asthma and Corticosteroid Responses in Childhood and Adult Asthma; Immunomodulators and Biologics; Bronchial Thermoplasty; Population Health Models for Asthma; and The Future of Asthma Care: Personalized Asthma Treatment.

This issue of Clinics in Chest Medicine, guest-edited by Dr. M. Patricia Rivera, is the first of two issues focused on Lung Cancer. Topics discussed in this issue include but are not limited to: Lung Cancer in the 21st Century; Epidemiology, Etiology, and Prevention; Lung Cancer in Women: A Modern Epidemic; Primary Prevention of Lung Cancer: Tobacco Treatment; The Biology of Lung Cancer: Development of More Effective Methods for Prevention, Diagnosis, and Treatment; Pathology of Lung Cancer; Lung Cancer Screening: Patient Selection and Implementation; The Approach to the Subsolid Nodule; Bronchoscopic Diagnostic Procedures Available to the Pulmonologist; Bronchoscopic Therapeutic Procedures Available to the Pulmonologist; and Biomarkers in Lung Cancer.