Tocotrienols

A New Avenue of Research Beyond Traditional Studies of Vitamin E In the current literature, more than 95% of all studies of vitamin E are directed toward the specific exploration of the bioactive component a-tocopherol. Until recently, there has been a dearth of research into non-tocopherol vitamin E molecules. A unique resource that examines the n

The first 90 years of vitamin E research has produced prolific and notable discoveries, but until the last few decades, attention has been given mostly to the biological activities and underlying mechanisms of alpha-tocopherol, which we now know is one of more than eight vitamin E isomers. Currently, the non-tocopherol vitamin E molecule tocotrienol has reached a new measure of research height: more than one-third of all vitamin E tocotrienol research of the last 30 years has been published since 2009. The thriving field of tocotrienol research gives ground for publication of Tocotrienols: Vitamin E Beyond Tocopherols, Second Edition, a compilation of the latest tocotrienol research in all new chapters. Highlights Established research, including prevention and treatment of cardiovascular disease, metabolic syndrome, and cancer Emergent research, including angiogenesis, bioavailability, bone health, gastric injury, inflammation, life extension, and skin health Tocopherol interference with tocotrienol functions All new chapters and many new contributors Recognized as potent antioxidants, tocotrienols play a role in cholesterol reduction, tumor suppression, reversal of arteriosclerosis, and protection of the heart against oxidative stress. Compiling contributions from leading researchers, this book overviews tocotrienols, and examines their sources, chemistry, and mechanisms of action. Contributors discuss the role of tocotrienols in the treatment and prevention of cancer and in cardiovascular health, diabetes, and other hormone regulation by tocotrienols. In addition, the book addresses animal and in vitro as well as mechanistic and pre-clinical studies. Dr. Tan discusses the benefits of tocotrienol in a YouTube video.

The first 90 years of vitamin E research has produced prolific and notable discoveries, but until the last few decades, attention has been given mostly to the biological activities and underlying mechanisms of alpha-tocopherol, which we now know is one of more than eight vitamin E isomers. Currently, the non-tocopherol vitamin E molecule tocotrienol has reached a new measure of research height: more than one-third of all vitamin E tocotrienol research of the last 30 years has been published since 2009. The thriving field of tocotrienol research gives ground for publication of Tocotrienols: Vitamin E Beyond Tocopherols, Second Edition, a compilation of the latest tocotrienol research in all new chapters. Highlights Established research, including prevention and treatment of cardiovascular disease, metabolic syndrome, and cancer Emergent research, including angiogenesis, bioavailability, bone health, gastric injury, inflammation, life extension, and skin health Tocopherol interference with tocotrienol functions All new chapters and many new contributors Recognized as potent antioxidants, tocotrienols play a role in cholesterol reduction, tumor suppression, reversal of arteriosclerosis, and protection of the heart against oxidative stress. Compiling contributions from leading researchers, this book overviews tocotrienols, and examines their sources, chemistry, and mechanisms of action. Contributors discuss the role of tocotrienols in the treatment and prevention of cancer and in cardiovascular health, diabetes, and other hormone regulation by tocotrienols. In addition, the book addresses animal and in vitro as well as mechanistic and pre-clinical studies. Dr. Tan discusses the benefits of tocotrienol in a YouTube video.

Vitamin E is a fat-soluble vitamin that exists in eight different forms. Each form has its own biological activity, which is the measure of potency or functional use in the body. Alpha-tocopherol (-tocopherol) is the name of the most active form of vitamin E in humans. It is also a powerful biological antioxidant. Vitamin E in supplements is usually sold as alpha-tocopheryl acetate, a form that protects its ability to function as an antioxidant. The synthetic form is labelled "D, L" while the natural form is labelled "D". The synthetic form is only half as active as the natural form. Antioxidants such as vitamin E act to protect the cells against the effects of free radicals, which are potentially damaging by-products of energy metabolism. Free radicals can damage cells and may contribute to the development of cardiovascular disease and cancer. Studies are underway to determine whether vitamin E, through its ability to limit production of free radicals, might help prevent or delay the development of those chronic diseases. Vitamin E has also been shown to play a role in immune function, in DNA repair and other metabolic processes. This new book presents leading research on this important topic.

In The Truth about Vitamin E: The Secret to Thriving with Annatto Tocotrienols, distinguished scientist and researcher Dr. Barrie Tan dives into his discovery of a new, natural form of vitamin E, annatto tocotrienol, and its amazing health benefits. For anyone who is currently suffering from a chronic condition, this book is a must-read! By the end of The Truth about Vitamin E: The Secret to Thriving with Annatto Tocotrienols, you will understand how this powerful antioxidant can lower cholesterol, reduce inflammation, protect your liver, promote bone health, increase survival rates in cancer patients, and even kill cancer cells. It's time to start living the healthy life you were meant to live!

Vitamin E is an important dietary constituent which helps in the defence against cellular damage. The process of its absorption from food and its utilization by the body is an intricate series of reactions. It is also used therapeutically in treating numerous diseases and conditions such as skin damage and the prevention of pathological lesions in major organs, and has been shown to be an important factor in preventing heart disease and cancer. Over 100 chapters from international contributors make this book the most comprehensive reference work in describing both the positive and negative effects and actions of Vitamin E. Chapters are divided into subsections which cover: nomenclature, biochemical, physical and chemical aspects of vitamn E related compounds; dietary and nutritional influences and effects; cocktails, anti-oxidants mixtures and novel analogues; general physiological systems, metabolism and metabolic stress; brain, neurological and optical systems; reproductive systems, fetus and infant; musculo-skeletal systems and exercise; cardiovascular and pulmonary systems; skin; hepatic, nephrotic and gastrointestinal systems; immune and haematological systems and cancer.

Employing a uniform, easy-to-use format, Vitamin Analysis for the Health and Food Sciences, Second Edition provides the most current information on the methods of vitamin analysis applicable to foods, supplements, and pharmaceuticals. Highlighting the rapid advancement of vitamin assay methodology, this edition emphasizes the use of improved and sophisticated instrumentation including the recent applications and impact of the widely adopted LC-MS. Designed as a bench reference, this volume gives you the tools to make efficient and correct decisions regarding the appropriate analytical approach--saving time and effort in the lab. Each chapter is devoted to a particular vitamin and begins with a brief review of its uniqueness and its role in metabolism. The authors stress a thorough understanding of the chemistry of each compound in order to effectively analyze it and to this end provide the chemical structure and nomenclature of each vitamin, along with tabular information on spectral properties. They supply extensive insight into practical problem-solving including an awareness of the stability of vitamins and their extraction from different biological matrices. All information is heavily documented with the latest scientific papers and organized into easily read tables covering topics necessary for accurate analytical results. After presenting the chemistry and biochemistry of the vitamin, each chapter details the commonly used analytical and regulatory methods. A summary table gives at-a-glance information on many of these sources, as well as several of the AOAC International Methods. In addition the authors apply their extensive experience in the field to create a critical, interpretive review of the advanced methods of vitamin analysis with sufficient detail to be a valuable guide to cutting-edge methodology.

Palm oil biomass is constantly produced in large quantities throughout the world as a waste product of the vast palm oil plantations. Biomass from the palm oil industry has been converted into value-added products to a limited extent via thermochemical, chemical, physical, and biochemical conversion routes. However, a significant amount of biomass, such as OPF and OPT, is still left in plantations. A pragmatic approach to converting them to value-added products will not only result in a cleaner environment but also generate significant revenue for the government. It is also suggested that more attention be paid to bioproducts in order to present them in an appealing form to end-users, thereby encouraging good patronage.