Transfer Factors Properties Mechanism Of Action And Its Clinical Applications

To date, transfer factors hold promise as one of the most exciting discovery in immunology and disease prevention. As the 21st century unfolds, these small molecules represent an important key to human health and well-being. Transfer factors are material present in dialysable leukocyte extracts capable of transferring cell-mediated immunity to pathogens. Transfer factors from one immune donor can be introduced into a non-immune recipient, potentially delivering an improved ability to fight threats to the recipient’s health. Similar to vaccines, transfer factors are prophylactic when administered prior to exposure to a pathogen. This book is an overview of basic immunology and the concept of transfer factors derived from past and current scientific publications. In this book, the properties, mechanism of action, and clinical applications of transfer factors are described. Since their discovery, evidence suggests transfer factors play an important role as immune modulators in treating diseases associated with the defective function of cell-mediated immunity such as cancer, infectious diseases, etc. The MF Plus Super Transfer Factor is then introduced including its function, characteristics, course, mode of administration, and advantages. The conclusion compiles research papers of transfer factor from years 2009 to 2020. This book will interest researchers and scientists in fields such as immunology, molecular medicine, biomedicine, immunotherapy, pathology, microbiology, and oncology.

Transfer Factor: Basic Properties and Clinical Applications covers papers about transfer factor. The book presents papers on the in vitro studies of transfer factor; the characterization of transfer factor; and the animal models of transfer factor. The text also includes articles on the use of transfer factor in infectious and neoplastic diseases and transfer factor therapy. Examples of papers on transfer factor therapy include the role of transfer factor in the treatment of lymphoma cutis in Wiskott-Aldrich syndrome, transfer factor immunotherapy of rheumatoid arthritis, and transfer factor therapy in a patient with an isolated T-cell deficiency. Immunologists, pathologists, oncologists, microbiologists and people involved in the study of infectious diseases will find the book invaluable.

Immune Regulators in Transfer Factor is a collection of papers presented at the Third International Symposium on Transfer Factor held on October 12-14, 1978 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors focus on immune regulators occurring in transfer factor, a dialyzable component of leukocyte lysates. The isolation and characterization of the immunologically active molecules, as well as tests for in vitro and in vivo, are described. This volume is organized into five sections encompassing 73 chapters and begins with an overview of animal models used in research on dialyzable leukocyte extracts, their modulation of suppressor activity, effects in mice, and activity and specificity of human and bovine transfer factor. The next section considers in vitro testing, touching on topics such as the quantification and biological assays of transfer factor; the specificity of transfer factor action on macrophage migration; and the effect of transfer factor therapy on antibody-dependent cytotoxic activity in humans. The reader is then introduced to the preparation, purification, and characterization of transfer factor, as well as clinical investigations ranging from phase I studies to randomized controlled trials. This book will be of interest to scientists and researchers in fields such as molecular medicine, biomedicine, microbiology, immunology, oncology, pathology, and immunotherapy.

Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycytidylic acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.

Monthly, with annual cumulations. Comprehensive, current index to periodical medical literature intended for use of practitioners, investigators, and other workers in community medicine who are concerned with the etiology, prevention, and control of disease. Citations are derived from MEDLARS tapes for Index medicus of corresponding date. Arrangement by 2 sections, i.e., Selected subject headings, and Diseases, organisms, vaccines. No author index.