Transport Phenomena In Microfluidic Systems

Fully comprehensive introduction to the rapidly emerging area of micro systems technology Transport Phenomena in Micro Systems explores the fundamentals of the new technologies related to Micro-Electro-Mechanical Systems (MEMS). It deals with the behavior, precise control and manipulation of fluids that are geometrically constrained to a small, typically sub-millimeter, scale, such as nl, pl, fl, small size, low energy consumption, effects of the micro domain and heat transfer in the related devices. The author describes in detail and with extensive illustration micro fabrication, channel flow, transport laws, magnetophoresis, micro scale convection and micro sensors and activators, among others. This book spans multidisciplinary fields such as material science and mechanical engineering, engineering, physics, chemistry, microtechnology and biotechnology. Brings together in one collection recent and emerging developments in this fast-growing area of micro systems Covers multidisciplinary fields such as materials science, mechanical engineering, microtechnology and biotechnology, et al Comprehensive coverage of analytical models in microfluidics and MEMS technology Introduces micro fluidics applications include the development of inkjet printheads, micro-propulsion, and micro thermal technologies Presented in a very logical format Supplies readers with problems and solutions

In this book, the fundamentals of chemical engineering are presented with respect to applications in micro system technology, microfluidics, and transport processes within microstructures. Special features of the book include the state-of-the-art in micro process engineering, a detailed treatment of transport phenomena for engineers, and a design methodology from transport effects to economic considerations.

This book provides readers from academia and industry with an up-to-date overview of important advances in the field, dealing with such fundamental fluid mechanics problems as nonlinear transport phenomena and optimal control of mixing at the micro- and nanoscale. The editors provide both in-depth knowledge of the topic as well as vast experience in guiding an expert team of authors. The review style articles offer a coherent view of the micromixing methods, resulting in a much-needed synopsis of the theoretical models needed to direct experimental research and establish engineering principles for future applications. Since these processes are governed by nonlinear phenomena, this book will appeal to readers from both communities: fluid mechanics and nonlinear dynamics.

Both experimental and numerical studies about the transport phenomena in microfluidic devices are presented in this thesis. The transport phenomena of interest are pressure driven flow and electroosmotic driven flow with a Reynolds number on the order of unit, and the associated mass transport phenomena. The studied microfluidic devices include fused silicon capillaries, in-house made glass microchannels and a glass chip with a crossing-linked microchannel etched into its surface. The hydraulic diameter ranges from 20 mum to 200 mum. The on-chip sample injection processes are studied both experimentally and numerically. Fluorescent dyes are employed here as the sample and the sample injection (loading and dispensing) processes on a microfluidic chip are visualized using an in-house developed laser visualization system and techniques. The experimentally measured sample injection process is compared with the numerical simulation results. Reasonable agreements were found between the model predictions and experimental measurements. The model is further developed in order to improve the simulation accuracy and save significant computation time as compared with the previous model. A general model capable of simulating general on-chip injection processes is finally developed to make the numerical analysis tools complete. This general model considers the electrical conductivity difference present at microfluidic applications, which is not considered normally due to its complexity. The electroosomotic flow is commonly applied in microfluidic devices as a pump, therefore, the flow rate determination is of particular interest. An experimental setup and corresponding data acquisition system are developed to measure electroosmotic flow rate by employing solution displacement process and current monitoring technique. A theoretical model is developed to improve the accuracy of this technique. A numerical model is developed to simulate this displacing process and to obtain flow rate. Good agreements between numerical simulations and experimental measurements verified the developed model. The electrokinetic transport phenomena of pressure driven flow in microchannels are studied based on a simultaneous solution to the developed pressure driven flow model. It is found that the flow characteristics of microchannels differ significantly from that in macrosized devices showing high viscous effects. The numerical results are compared with the experimental measurements and good agreement verified the developed model.

Microfluidic systems are devices that take advantage of the physical and chemical properties of liquids and gases and the electrical properties of semiconductors and combine them on a single chip. The field of microfluidics is experiencing tremendous growth in the biomedical area as new advances in silicon and other materials have brought forth much better and smaller microchannels for fluid applications. Microfluidic Sytsems focuses on flow, transport, and basic chemical phenomena as motivated by the surge in interest in microfluidic systems and bioMEMS. It provides access to the field for readers who may have had limited exposure to transport phenomena in the past, but who want to become proficient in the myriad of transport and reaction issues related to designing a microfluidic system. Readers having a knowledge of fluid mechanics that focus mainly on high Re flows, but lacking training in low Re flows or electrokinetics will also benefit from this text. In addition, numerous exercises and cases studies as well as solutions are included.

Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.

Microfluidics is a microtechnological field dealing with the precise transport of fluids (liquids or gases) in small amounts (e.g. microliters, nanoliters or even picoliters). This book provides a useful introduction into this burgeoning field, and a specific application of microfluidics is presented. It also gives a survey of microfluidics.

The advancements in micro- and nano-fabrication techniques, especially in the last couple of decades, have led research communities, over the world, to invest unprecedented levels of attention on the science and technology of micro- and nano-scale devices and the concerned applications. With an intense focus on micro- and nanotechnology from a fluidic perspective, Microfluidics and Microscale Transport Processes provides a broad review of advances in this field. A comprehensive compendium of key indicators to recent developments in some very active research topics in microscale transport processes, it supplies an optimal balance between discussions of concrete applications and development of fundamental understanding. The chapters discuss a wide range of issues in the sub-domains of capillary transport, fluidic resistance, electrokinetics, substrate modification, rotational microfluidics, and the applications of the phenomena of these sub-domains in diverse situations ranging from non-biological to biological ones like DNA hybridization and cellular biomicrofluidics. The book also addresses a generic problem of particle transport in nanoscale colloidal suspensions and includes a chapter on Lattice-Boltzmann methods for phase-changing problems which represents a generic particle based approach that may be useful to address many microfluidic problems of interdisciplinary relevance.