Understanding Biochemical Pathways

Understanding Biochemical Pathways: A Pattern-Recognition Approach is designed to serve as a companion text to standard biochemistry textbooks. The book lays out a clear methodology for mastering biochemical pathways through pattern recognition, as well as how specific enzymes are named. The approach is illustrated through particular examples of pathways in carbohydrate and lipid metabolism. Students will learn about oxidation state patterns, and metabolism and glycolysis. They will study the pyruvate dehydrogenase complex and the tricarboxylic acid cycle. They will also explore the electron transport chain, gluconeogenesis, and the pentose phosphate pathway. The final chapters are devoted to fatty acid oxidation, and ketone body and fatty acid synthesis. Understanding Biochemical Pathways provides readers with a set of critical questions regarding any specific pathway that, when answered, enable them to understand the "big picture" of that metabolic pathway, and how pathways are regulated and integrated. The book is an excellent addition to any course in biochemistry, particularly undergraduate courses, as well as in nutrition, medical, and nursing programs.

The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “... highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)

Biochemistry Explained employs an innovative approach which has proven highly successful in the author's own classes. The author establishes a thorough understanding of the foundations of and common linkages between molecular structures and reactions, so that eventual interpretation of complex biochemical pathways and reactions is easy. All of the major molecular structures and biochemical pathways are explained, and, for the most part, these center on mammalian biochemistry. The text is supported by biochemical nomenclature and questions to bear in mind while reading. Higher learning sections are also provided for advanced students. Written in an informal, conversational style, this textbook will serve as an invaluable resource for any student who is struggling with the standard texts and for postgraduate students who need to refresh their knowledge.

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.

Intended for advanced undergraduates and graduate students in all areas of biochemistry, The Organic Chemistry of Biological Pathways provides an accurate treatment of the major biochemical pathways from the perspective of mechanistic organic chemistry.