Viral Immunology And Immunopathology

Viral Immunology and Immunopathalogy covers topics concerning the role of cellular and humoral immunity in viral infections, factors responsible for the persistence and recurrence of viral infections in the presence of immunity, mechanisms of viral immunopathology, and concepts in the development of vaccines. The book describes the history of viral immunology; the synthesis and properties of viral antigens; and the humoral immune response to viruses. The text also discusses the mechanisms of viral neutralization; cellular immunity; the role of inflammatory cells and effector molecules in combating viral infections; and the genetic control of resistance. The book concludes with chapters on herd immunity; viral immunopathology; and viral immunology and immunopathology. Immunologists, pathologists, virologists, and microbiologists will find the book useful.

Immunopathology, Volume 107 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Viral Immunopathology will cover how the immune system, innate or adaptive, is often at the root of viral pathogenesis. This is true in diverse host systems including vertebrates, plants and insects. This volume will present the latest findings in this interesting and important area of research, and will include human, plant, fish, and insect viruses. Different kingdoms have evolved very diverse immune responses to virus infection but the common theme – namely, that effects of viruses on host immune systems can condition the induction of viral disease – will unify this concept across kingdoms. The immune system is often responsible for virus pathology Plants, animals and insects all mount immune responses to virus infection that can increase pathology Both innate and adaptive immune responses can result in immunopathology

Membranes and Viruses in Immunopathology covers the proceedings of the 1972 symposium by the same title, held at the University of Minnesota Medical School, sponsored by the Bell Museum of Pathology. This book is composed of 40 chapters that highlight the significant advances in fundamental experiments of membrane structure chemistry. Considerable chapters explore the diagnosis and analysis of slow and oncogenic virus infections, as well as the role of immunobiologic processes in the pathogenesis, prevention, and treatment of disease. The remaining chapters contain research works on the detailed mechanisms that may contribute to cancer induction and dissemination. This book will prove useful to immunopathologists and practicing physicians.

This publication, "Viruses, Immunity and Immunodeficiency," is based on the first symposium in a series of International Biomedical Symposia sponsored by the College of Medicine of the University of South Florida in Tampa, Florida. There is an explosive interest concerning the effects of viruses on the immune response, especially the immunosuppressive effects of viral infection. This has come about because of the recognition that the Acquired Immunodeficiency Syndrome, which has taken biomedical scientists and the public in general by surprise, is just one of the many examples that viruses can influence the immune response system and, under appropriate circumstances, alter immunity in such a way that an infected individual becomes hi~lly susceptible to a variety of other organisms to which normal individuals would be resistant. This symposium series, sponsored by the University of South Florida College of Medicine, brings to the biomedical con®unity topics of current interest. We thank the members of the faculty of various departments of the College of Medicine and the administration of the College for their support and encouragement in having these symposiaat this medical school. This volume, based or. this symposium onviruses and immunity is a good exam ple of the interdisciplinary nature of modern irrJ!1I1nobiology and modern biomedical science in general. Many investigators with many different back grounds and training experiences, including microbiologists, immunologists, biochemists, oncologists, and physicians, are interested in how and why viruses influence the immune response system.

This text provides a coherent and concise introduction to the field of viral pathogenesis and immunity. The text is divided into four sections which highlight the fundamental principles within this field of study. Section 1, Essentials of Viral Pathogenesis, describes the sequential events in viral infection, the localization of viral infections and the variety of virus-cell interactions. Section 2, Host Responses to Viral Infection, examines immune responses including virus-induced immunopathology and immunosuppression. Section 3, Virus-Host Interactions, covers virulence, viral persistence, virus-induced oncogenesis and host susceptibility. Section 4, Prevention of Viral Infections, explains the key principles of vaccine development.

We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). Prof. Leopoldo Santos-Argumedo is the President of the Latin American Association of Immunology (ALAI); Prof. Rosana Pelayo is the President of Sociedad Mexicana De Inmunología (SMI) and Prof. Luis García is a former ALAI President.

The sixth edition of this best-selling textbook presents a systematic account of the effects, both good and bad, of the immune system. Special emphasis is placed on what the immune system actually does in causing and preventing disease. Divided into two parts, the sixth edition discusses inflammation, the fundamentals of the immune system and how it is activated, the seven immune effector mechanisms, and how these effector mechanisms act not only to protect against infection and cancer but also to cause diseases. Valuable reading for physicians, medical students, graduate students, nurse practitioners, physician assistants, teachers of immunology, and advanced courses in immunology.