Alicyclic Compounds

Rodd's Chemistry of Carbon Compounds, Volume II: Alicyclic Compounds surveys advances in the chemistry of three- to six-membered monocarbocycles from 1973 to 1991. This book begins with a detailed review of the conformations and stereochemical analyses of alicycles, including higher members of the series, and then proceeds to deal with the chemistry of individual ring systems. The next chapters cover the prostaglandins and their allies and natural products bearing a cyclohexane, cyclohexene, or cyclohexadiene ring system. A review of the chemistry of the cyclohexadienes and their metallic complexes is provided at the end. This text also includes a list of common abbreviations and symbols. This volume benefits chemical engineering students, particularly those studying the components of organic chemicals.

Rodd's Chemistry of Carbon Compounds, Volume II: Alicyclic Compounds focuses on alicyclic chemistry. The book first ponders on acyclic and monocyclic monoterpenoids, including artemisyl, santolinyl, chrysanthemyl, and other irregular systems; naturally occurring halogenated monoterpenoids; cyclobutanes; and tetramethylcyclohexanes. The text discusses the carotenoid group of natural products. Trends in carotenoid chemical research; improved methodology; optical isomerism including aliene isomerism; and geometrical isomerism are described. The book discusses cycloheptanes and cyclooctanes, large alicyclic ring systems, and polycarbonic compounds with separate ring systems and spiro compounds. The text describes polycyclic compounds and polycarbocyclic bridged ring compounds, and then discusses bicarbocyclic natural products. The Wagner-Meerwein rearrangement; camphor and related compounds; fenchone and related compounds; and carane, thujane, and pinane groups are also considered. The text is a valuable reference for readers interested in the study of carbon compounds.

Alicyclic Compounds

Volume I of this two-part series provides thorough coverage of aliphatic compounds, devoting 500 pages to their physical properties and various methods of synthetic preparation. It also discusses alicyclic compounds and their reactions, isomers, and processes. 1951 edition.

Advances in Alicyclic Chemistry, Volume 1 brings together numerous research works on the chemistry of alicyclic compounds. This volume is divided into five chapters and begins with an evaluation of the chemistry of small bicyclic systems and cyclopropenes. The subsequent chapters examine the reactions of six- and seven-membered ring cyclohexadiones and tropolones. The final chapter focuses on the theoretical and experimental aspects of bridgehead reactivity. This book will be of value to organic chemists and graduate students.

This book is designed to give an illustrative rather than an encyclopaedic view of the fascinating world of alicyclic compounds. It is focused on the basic topics of structure and chemical transformations. The classification and structural description of alicyclic compounds and an assessment of their stability is followed by the treatment of processes characterizing their dynamic behaviour. Further chapters describe useful methods for the synthesis of alicyclics by ring contraction, ring enlargement and transannular cyclization. Finally, the application of alicyclics for the construction of important natural products or interesting model compounds is discussed. The extensive bibliography of more than 1500 references and detailed subject index will be particularly useful. The book will be of interest to graduate students and lecturers in organic and physical organic chemistry, as well as to research chemists at universities and in the fine chemical, pharmaceutical and fragrance industries.

Through numerous conversations with other synthetic chemists it became apparent that the great power of carbon nuclear magnetic resonance was being significantly underutilized. In our own work we have found that 13C spectroscopy is a more powerful tool than IH NMR spectroscopy, especially for probing subtle stereochemical questions in complicated systems. This is especially true in five membered ring compounds where IH NMR is at a particular disadvantage. The two techniques can be used independently to solve the same question-that of stereochemistry - but they do so in different ways. Advantage can be taken in IH NMR of a relatively consistent relationship between stereochemical orientation and coupling constants between vicinal protons, while in 13C NMR it is the correlation between spatial relationships of non-hydrogen, y substituents and their effect on chemical shift that can be used to assign stereochemistry. It was also clear that the use of 13C NMR required a different approach to problem solving than that typically used with IH NMR. While the latter technique could be employed with a very general approach (e.g., the Karplus equation), 13C NMR would, at least for the immediate future, require a relatively extensive set of model systems from which the consequences of stereochemical changes could be derived for any given carbon framework.