Anesthesia And Neurotoxicity

This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction. It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and cognitive dysfunction, potential ways to prevent or alleviate them and the public health implications. Recently, it has been shown that using anesthetics on the developing brain causes apoptotic neurodegeneration and persistent learning/memory deficits later in life. Anesthesiologists need more information on this mechanism in the human brain. The negative effects of anesthesia and surgery on the nervous system have attracted attention lately; this book provides physicians, researchers, and postdocs with invaluable information on this topic.

Anesthetic Neurotoxicity in Pediatric Patients book Since the beginning of the modern anesthesia (nearly 170 years), millions of people have received inhalation anesthetics, intravenous anesthetics, or a combination in order to create general anesthesia. These drugs have been applied in all age groups, from newborns who may be only a few hours old to geriatric patients. In fact, pediatric patients comprise a significant proportion of the total number of patients treated with general anesthesia, a trend that will continue well into the future. Covering both surgical and anesthetic considerations, Anesthetic Neurotoxicity in Pediatric Patients book is an essential resource for formulation of an anesthetic plan and perioperative management of patients. All chapters are written by both surgeons and anesthesiologists, giving you a detailed, real-world perspective on the many variables that accompany today's surgical procedures FEATURES: Specifications: Presents preoperative, intraoperative, and postoperative anesthetic considerations in a clear, templated format, summarizing all courses of action in easy-to-read tables. Fist view: Features a full-color design to enhance readability of the tables and clarity of the illustrations. Utility: Describes what the surgeon will likely be doing, variants of the procedure or approaches, patient population characteristics, and details of the procedure including positioning, length of procedure, postop care, and more. Use Right Away: Easy to flip the paper. Value: A concise and easily referable guide ideal for use during anesthesiology residency training and fellowships. Helpful illustrations and a bulleted content for rapid reference: This book is a valuable resource for all anesthesiology and cardiac critical care providers who manage patients with congenital heart disease, and an ideal study aid. Durable Construction: Quality and sturdy paper resists curling and ink bleed-through, and durable binding ensures longevity throughout the year. Recommendation: Presents preoperative, intraoperative, and postoperative anesthetic considerations in a clear, templated format, summarizing all courses of action in easy-to-read tables. Anesthetic Neurotoxicity in Pediatric Patients book is to provide an initial exposure to a variety of pediatric cases. The length of this rotation, 4 weeks, is enough to allow participation in the care of about 100 patients. Residents on this rotation should be able to develop skills for setting up OR for pediatric patients of different ages and should master skills in mask ventilation and intubation of pediatric patients including neonates. Topics for discussion should include neonatal emergencies, pediatric airways, ETT cases, general surgical cases, and questions from written and oral boards. One of the goals of this rotation is to prepare residents for routine "bread and butter" cases, to be safe with pediatric patients, and to be able to identify situations in which he or she might need help.

This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important clinical challenges encountered in day-to-day practice in the OR, the PACU, and the ICU and is designed as a problem-solving tool for all members of the perioperative medicine team: trainees and faculty in anesthesiology, neurosurgery, and critical care; nurses; nurse anesthetists; and physician’s assistants. • Encompasses clinical continuum from neurosurgical pre-op to critical care – plus anesthesia in neuroradiology • Adult and pediatric care • Structured algorithmic approach supports clinical decision-making • Succinct presentation of clinically relevant basic science • End-of-chapter summaries, with suggestions for further reading • Collaborative approach and multidisciplinary nature of perioperative medicine emphasized • Extensive summary tables • Portable and formatted for quick retrieval of information • Ideal for use in the OR, the PACU, and the ICU

This book highlights remarkable new endoscopic, laparoscopic, and thoracoscopic approaches to the removal of surgical lesions for different pathologic conditions under general endotracheal anesthesia in infants and children. It details how newer techniques in airway management, monitoring, regional nerve blocks for these innovative minimally invasive approaches have resulted in a decrease in intraoperative and postoperative morbidity and early recovery process after pediatric anesthesia. This unique book contains features that provide the audience with several clinical scenarios where exceptional surgical outcomes are achieved with optimum pre-op preparation via collaborative team efforts. To date there is no other textbook emphasizing the anesthetic and surgical management during the most innovative advances in endoscopic surgery in children. Per oral endoscopic myotomy (POEM) for the definitive treatment of achalasia in children is probably the most advanced endoscopic surgery done successfully in children. POEM is the best example of endoscopic surgery performed via natural orifices known as the Natural orifice transluminal endoscopic surgery (NOTES). Another new laparoscopic surgical intervention -Median Arcuate Ligament surgical release for Median Arcuate Ligament Syndrome (MALS) for patients with Postural Orthostatic Tachycardia Syndrome (POTS) is described with established perioperative protocols emphasizing the need for early admission, intravenous hydration, and premedication. Novel approaches in the anesthetic management in children with short bowel syndrome for bowel lengthening techniques like the serial transverse enteroplasty (STEP) and in teenagers for laparoscopic bariatric surgery with adjustable gastric banding (AGB) and vertical sleeve gastrectomy (VSG) for morbid obesity are new areas that would enlighten the readers. Anesthetic Management in Pediatric General Surgery is an invaluable resource for pediatric anesthesiologists, surgeons, and their trainees specializing in the care of pediatric patients.

The book provides an excellent review of all the clinical aspects of neuroanesthesia in children, including neurosurgeries during fetal state to neonatal, infancy, toddler, and school-going age groups. To provide optimal anesthetic care in children undergoing neurosurgery, the care provider must have adequate knowledge on the developing brain and spinal cord, and the effect of anesthetics on the neuronal tissue, and the inherent issues pertaining to neurologic lesions. This book covers the diagnostic, imaging, surgical as well as anesthetic managements of all the neurosurgical problems in children. The chapters include a wide range of topics from basic neurophysiology to general concerns for pediatric neuroanesthesia, including fluid management, blood transfusion, temperature regulation, and surgical positioning, as well as specific issues such as anesthesia for brain tumor surgery, hydrocephalus, neural tube defects, cerebrovascular surgeries such as aneurysmal surgery, arteriovenous malformations (AVMs), Moyamoya disease, and vein of Galen malformation, functional neurosurgery, epilepsy surgery, neuroendoscopy, craniovertebral junction anomalies, spinal surgeries, neurotrauma, and brain abscess with congenital heart diseases. Interesting topics like neuroanesthesia in remote locations, regional anesthesia during neurosurgery, and anesthesia for children with neuromuscular disease are also discussed. Moreover, the book elaborates on advanced neuroanesthesia techniques during fetal neurosurgery and craniopagus separation surgery; and the postoperative intensive care management aspects in each chapter. It is supplemented with figures depicting surgical procedures and positioning, neuroimages, tables and illustrations for easy understanding. This book caters to neuroanesthesiologists, pediatric anesthesiologists, residents, and fellows of anesthesia or neuroanesthesia, practicing anesthesiologists, pediatric neurointensivists, nurse anesthetists, neurosurgeons, and pediatric neurosurgeons. It also serves as a reference book for the DM (neuroanesthesiology and neurocritical care), DNB-SS (neuroanesthesiology), and MD (anesthesiology) curriculums apart from anesthesia residency and pediatric anesthesia/ neurosurgery fellowship programs offered at various Institutions worldwide.

The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

The advancement of tactics used in managing pediatric airway disorders can be attributed to an overall growth of collective knowledge among medical health professionals. This book is designed to sustain that growth of knowledge, with 18 chapters of insight and information by distinguished medical experts in both pediatric anesthesia and pediatric otolaryngology. It concisely and thoroughly covers topics such as subglottic stenosis, pharyngeal airway obstruction, laryngeal airway obstruction, obesity and sleep apnea and thoracic airway obstruction, among others. Chapters include scenarios where the skills and expertise of both anesthesiologists and otolaryngologists are being continually tested; the use of newer drugs and repurposing of older drugs; the combination of smaller amounts of different types of sedatives while avoiding intra-op narcotics and maintaining spontaneous ventilation are described in detail; Finally, a comprehensive review of new research emerging about ultra-rapid narcotics metabolizers among patients, making them more susceptible to medications, such as codeine, along with the latest information on the purported potential neurodevelopmental toxicity of some anesthetic agents are also included. Working as both an educational tool and a practical resource, medical practitioners, students and educators will find this text to be a valuable tool for the safely managing the pediatric patient undergoing anesthesia for difficult airway scenarios.