Animal Origin Viral Zoonoses

This book is the second volume in the series Livestock Diseases and Management, and reviews the importance and implications of animal origin viral zoonoses. It also highlights the specific etiology and epidemiology of these viral infections and discusses their various biological and mechanical transmission mechanisms. Further, the book reviews various measures for controlling viral zoonoses and examines novel therapeutic and prophylactic strategies. Discussing recent studies on the pathogenesis and host immune response to these infections, it underscores the importance of using vaccines against these viral diseases to reduce the risk of them being transmitted to humans.Lastly, it describes in detail the challenges posed by these viral infections and our readiness to face them.

Since the central theme of this book is the transmission of disease agents through the food chain, we will examine influenza viruses from this perspective. Influenza A viruses are found in humans, pigs, horses, sea mammals, and also in wild aquatic and domestic birds [23]. How are they spread? Between mammals, influenza is an airborne infection, but between birds, influenza can be either an airborne or waterborne infection. Influenza viruses of aquatic birds periodically transmit to domestic birds sometimes with catastrophic effects; this transmis sion can be either airborne or waterborne. Less frequently, avian influenza viruses transmit to mammals and three to four times in the past century this transmission has initiated a pandemic of influenza in humans. The method of spread of avian influenza viruses to mammals remains unresolved, but could be either airborne or waterborne. In this report we will consider recent examples of interspecies transmission of influenza A viruses and the possible prevention of emergence of the next human pandemic which is considered imminent. The reservoirs of influenza A viruses The available evidence indicates that aquatic birds are the reservoirs of all 15 subtypes of influenza A viruses. We will first consider the replication of influenza A in aquatic birds. In wild ducks, influenza viruses replicate preferentially in the cells lining the intestinal tract, cause no disease signs, and 8 7 are excreted in high concentrations in the feces (up to 10 .

This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and prevent them. The chapters are written by internationally recognized scientists in their respective areas of disease, who work or have worked extensively in the most affected areas of the world. The emphasis for each zoonosis is on the epidemiology of the disease, the clinical syndromes and carrier states in infected animals and humans, and the most current methods for diagnosis and approaches to control. For infectious agents or biologic toxins, which may be transmitted by foods of animal origin, a strong focus is placed on food safety measures. The etiologic and therapeutic aspects of each disease important to epidemiology and control are identified.

"This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and prevent them. The chapters are written by internationally recognized scientists in their respective areas of disease, who work or have worked extensively in the most affected areas of the world. The emphasis for each zoonosis is on the epidemiology of the disease, the clinical syndromes and carrier states in infected animals and humans, and the most current methods for diagnosis and approaches to control. For infectious agents or biologic toxins, which may be transmitted by foods of animal origin, a strong focus is placed on food safety measures. The etiologic and therapeutic aspects of each disease important to epidemiology and control are identified."--Provided by publisher.

This second fully revised and extended edition of “Zoonoses - Infections Affecting Humans and Animals” covers the most important pathogens impacting both human and animal public health and debates current developments in this interdisciplinary field from a One Health perspective. Following a "setting" approach, the individual chapters each review zoonoses occurring in a specific group of animals, such as production animals, pets or wildlife, or in a defined ecosystem. A focus is put on zoonoses emerging along the food chain and on antibiotic resistance as an increasing challenge in infectious disease management. Special interest chapters debate non-resolved and currently hotly debated zoonoses, foremost COVID-19, influenza, Crohn/paratuberculosis and chronic botulism, also taking into account the economic and ecological aspects of zoonotic disease outbreaks. This second edition includes brand-new chapters on emerging pathogens such as SARS-CoV-2, chlamydia and helminths, it reviews historic zoonoses, provides additional insights into pathogens of reptiles and highlights significant neglected tropical diseases. This reference work is a must-read for researchers, health professionals and students in Microbiology and Veterinary Medicine. The book’s ambition to spread knowledge on zoonoses and on strategies on how to tackle them complies with the United Nations Sustainable Goals, in particular Goal 3 – Good Health and Well-Being.

Zoonotic diseases represent one of the leading causes of illness and death from infectious disease. Defined by the World Health Organization, zoonoses are "those diseases and infections that are naturally transmitted between vertebrate animals and man with or without an arthropod intermediate." Worldwide, zoonotic diseases have a negative impact on commerce, travel, and economies. In most developing countries, zoonotic diseases are among those diseases that contribute significantly to an already overly burdened public health system. In industrialized nations, zoonotic diseases are of particular concern for at-risk groups such as the elderly, children, childbearing women, and immunocompromised individuals. The Emergence of Zoonotic Diseases: Understanding the Impact on Animal and Human Health, covers a range of topics, which include: an evaluation of the relative importance of zoonotic diseases against the overall backdrop of emerging infections; research findings related to the current state of our understanding of zoonotic diseases; surveillance and response strategies to detect, prevent, and mitigate the impact of zoonotic diseases on human health; and information about ongoing programs and actions being taken to identify the most important needs in this vital area.

Brucellosis, also known as undulant fever, Mediterranean fever, or Malta fever, is an important human disease in many parts of the world. It is a zoonosis and the infection is almost invariably transmitted to people by direct or indirect contact with infected animals or their products. These Guidelines are designed as a concise, yet comprehensive, statement on brucellosis for public health, veterinary and laboratory personnel without access to specialized services. They are also to be a source of accessible and updated information for such others as nurses, midwives and medical assistants who may have to be involved with brucellosis in humans. Emphasis is placed on fundamental measures of environmental and occupational hygiene in the community and in the household as well as on the sequence of actions required to detect and treat patients.

The beginning of the 21st century was marked by an increase in the number of emerging/reemerging infectious diseases detected worldwide and by the challenging COVID-19 pandemic. Most of these emerging diseases are caused by viruses that are primarily RNA viruses of animal origin, with a long history of adaptation to their natural hosts, becoming pathogenic when crossing species barriers. The conditions for viral persistence in animal reservoirs, particularly among the very diverse species of rodents and bats, and pathogenicity in humans are not always elucidated. Meanwhile, outbreaks are influenced by human activities that disrupt ecosystems and increase contact between infected animals and humans. Therefore, population dynamics are of great importance, with domestic animals playing key roles as intermediaries in the transmission of viruses. Considering the increase in emerging infectious disease and their occurrence on a global scale, damage to ecosystems, mainly caused by human activities that, thereby increase contact between wild animals, domestic animals, and humans, the global "One Health" approach is essential. The articles published in the Special Issue, "Viral Zoonoses: Interactions and Factors Driving Virus Transmission ", contribute to this reflection.