Applied Statistics In Toxicology And Pharmacology
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Applied Statistics in Toxicology and Pharmacology
Author | : Katsumi Kobayashi,K. Sadasivan Pillai |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2003 |
Genre | : Pharmacology |
ISBN | : 1578083044 |
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This book will serve as an excellent field guide to applied toxicology and pharmacology investigators. It is an easy-to-read compilation of topics in applied statistics that might be considered a FAQ or perhaps more properly, a compilation of answers to questions that should be frequently asked, but often are not.
A Handbook of Applied Statistics in Pharmacology
Author | : Katsumi Kobayashi,K. Sadasivan Pillai |
Publsiher | : CRC Press |
Total Pages | : 230 |
Release | : 2012-10-18 |
Genre | : Mathematics |
ISBN | : 9781466515406 |
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Statistics plays an important role in pharmacology and related subjects such as toxicology and drug discovery and development. Improper statistical tool selection for analyzing the data obtained from studies may result in wrongful interpretation of the performance or safety of drugs. This book communicates statistical tools in simple language. The
Statistics in Toxicology Using R
Author | : Ludwig A. Hothorn |
Publsiher | : CRC Press |
Total Pages | : 294 |
Release | : 2016-01-13 |
Genre | : Mathematics |
ISBN | : 9781498786751 |
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The apparent contradiction between statistical significance and biological relevance has diminished the value of statistical methods as a whole in toxicology. Moreover, recommendations for statistical analysis are imprecise in most toxicological guidelines. Addressing these dilemmas, Statistics in Toxicology Using R explains the statistical analysi
Statistics In the Pharmaceutical Industry 3rd Edition
Author | : Charles Ralph Buncher,Jia-Yeong Tsay |
Publsiher | : CRC Press |
Total Pages | : 606 |
Release | : 1993-11-17 |
Genre | : Mathematics |
ISBN | : 0824790731 |
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This rewritten and updated second edition provides comprehensive information on the wide-ranging applications of statistics in the pharmacological field. Focusing on practical aspects, it sets out to bridge the gap between industry and academia.;Reflecting the changes that have taken place since publication of the first edition, this volume covers new topics such as: cancer clinical trials, clinical trials of AIDS patients and animal tumorigenicity studies; the development of antiepileptic drugs; the role of epidemiology in postmarketing trials and adverse drug experience; computer-assisted new drug application (CANDA) submissions; contract research organizations; interim analysis in clinical trials; and room-temperature tests for the stability of drugs.;This work is intended as: a reference for statisticians, biostatisticians, pharmacologists, administrators, managers, and scientists in the pharmaceutical industry; and a text for graduate students taking courses in applied statistics or pharmaceutical statistics.
Nonclinical Statistics for Pharmaceutical and Biotechnology Industries
Author | : Lanju Zhang |
Publsiher | : Springer |
Total Pages | : 698 |
Release | : 2016-01-13 |
Genre | : Medical |
ISBN | : 9783319235585 |
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This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods important to the nonclinical science areas within the pharmaceutical and biotechnology industries. Specifically the Discovery and Translational sciences, the Safety/Toxiology sciences, and the Chemistry, Manufacturing and Controls sciences. Drug discovery and development is a long and costly process. Most decisions in the drug development process are made with incomplete information. The data is rife with uncertainties and hence risky by nature. This is therefore the purview of Statistics. As such, this book aims to introduce readers to important statistical thinking and its application in these nonclinical areas. The chapters provide as appropriate, a scientific background to the topic, relevant regulatory guidance, current statistical practice, and further research directions.
Applied Statistics in the Pharmaceutical Industry
Author | : Steven P. Millard,Andreas Krause |
Publsiher | : Unknown |
Total Pages | : 536 |
Release | : 2014-09-01 |
Genre | : Electronic Book |
ISBN | : 1475734670 |
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Statistics for Toxicologists
Author | : Salsburg |
Publsiher | : CRC Press |
Total Pages | : 220 |
Release | : 1986-05-29 |
Genre | : Mathematics |
ISBN | : 0824775902 |
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This book explains how the computer programs work and why and when they can be applied to problems in toxicology. It discusses the statistical models used and their applications in a general fashion. The book overviews the problems that can arise from the blind use of the statistical models.
Statistics and Experimental Design for Toxicologists and Pharmacologists Fourth Edition
Author | : Shayne C. Gad |
Publsiher | : CRC Press |
Total Pages | : 600 |
Release | : 2005-07-18 |
Genre | : Medical |
ISBN | : 0849322146 |
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Purposefully designed as a resource for practicing and student toxicologists, Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition equips you for the regular statistical analysis of experimental data. Starting with the assumption of basic mathematical skills and knowledge, the author supplies a complete and systematic yet practical introduction to the statistical methodologists available for, and used in, the discipline. For every technique presented, a worked example from toxicology is also presented. See what's new in the Fourth Edition: The first practical guide to performing meta analysis allowing for using the power inherent in multiple similar studies Coverage of Bayesian analysis and data analysis in pharmacology and toxicology Almost 200 problems with solutions Discussion of analysis of receptor binding assays, safety pharmacology assays and other standard types conducted in pharmacology A new chapter explaining the basics of Good Laboratory Practices (GLPs) For those with computer skills, this edition has been enhanced with the addition of basic SAS Written specifically for toxicologists and pharmacologists, the author draws on more than 30 years of experience to provide understanding of the philosophical underpinnings for the overall structure of analysis. The book's organization fosters the ordered development of skills and yet still facilitates ease of access to information as needed. This Fourth Edition gives you the tools necessary to perform rigorous and critical analysis of experimental data and the insight to know when to use them.