Basic Clinical Biostatistics Fifth Edition

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Learn to evaluate and apply statistics in medicine, medical research, and all health-related fields Basic & Clinical Biostatistics provides medical students, researchers, and practitioners with the knowledge needed to develop sound judgment about data applicable to clinical care. This fifth edition has been updated throughout to deliver a comprehensive, timely introduction to biostatistics and epidemiology as applied to medicine, clinical practice, and research. Particular emphasis is on study design and interpretation of results of research. The book features “Presenting Problems” drawn from studies published in the medical literature, end-of-chapter exercises, and a reorganization of content to reflect the way investigators ask research questions. To facilitate learning, each chapter contain a set of key concepts underscoring the important ideas discussed. Features: • Key components include a chapter on survey research and expanded discussion of logistic regression, the Cox model, and other multivariate statistical methods • Extensive examples illustrate statistical methods and design issues • Updated examples using R, an open source statistical software package • Expanded coverage of data visualization, including content on visual perception and discussion of tools such as Tableau, Qlik and MS Power BI • Sampling and power calculations imbedded with discussion of the statistical model • Updated content, examples, and data sets throughout

The ideal way to develop sound judgment about data applicable to clinical care First choice of students, educators, and practitioners A thorough, meaningful, and interesting presentation of biostatistics Helps students become informed users and consumers of biostatistics Learn to evaluate and apply statistics in medicine, medical research, and all health-related fields. Emphasis on the basics of biostatistics and epidemiology and the clinical applications in evidence-based medicine and decision-making methods NEW chapter on survey research Expanded discussion of logistic regression, the Cox model, and other multivariate statistical methods Key Concepts in each chapter pinpoint essential information Presenting Problems drawn from studies in the medical literature that illustrate the various statistical methods Downloadable NCSS statistical software, procedures, and data sets from the presenting problems End-of-chapter exercises Multiple-choice final practice exam

CD-ROM contains: Coverage of research and design methods -- Statistical software and data sets.

In clinical medicine appropriate statistics has become indispensable to evaluate treatment effects. Randomized controlled trials are currently the only trials that truly provide evidence-based medicine. Evidence based medicine has become crucial to optimal treatment of patients. We can define randomized controlled trials by using Christopher J. Bulpitt’s definition “a carefully and ethically designed experiment which includes the provision of adequate and appropriate controls by a process of randomization, so that precisely framed questions can be answered”. The answers given by randomized controlled trials constitute at present the way how patients should be clinically managed. In the setup of such randomized trial one of the most important issues is the statistical basis. The randomized trial will never work when the statistical grounds and analyses have not been clearly defined beforehand. All endpoints should be clearly defined in order to perform appropriate power calculations. Based on these power calculations the exact number of available patients can be calculated in order to have a sufficient quantity of individuals to have the predefined questions answered. Therefore, every clinical physician should be capable to understand the statistical basis of well performed clinical trials. It is therefore a great pleasure that Drs. T. J. Cleophas, A. H. Zwinderman, and T. F. Cleophas have published a book on statistical analysis of clinical trials. The book entitled “Statistics Applied to Clinical Trials” is clearly written and makes complex issues in statistical analysis transparant.

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Basic Biostatistics is a concise, introductory text that covers biostatistical principles and focuses on the common types of data encountered in public health and biomedical fields. The text puts equal emphasis on exploratory and confirmatory statistical methods. Sampling, exploratory data analysis, estimation, hypothesis testing, and power and precision are covered through detailed, illustrative examples. The book is organized into three parts: Part I addresses basic concepts and techniques; Part II covers analytic techniques for quantitative response variables; and Part III covers techniques for categorical responses. The Second Edition offers many new exercises as well as an all new chapter on "Poisson Random Variables and the Analysis of Rates." With language, examples, and exercises that are accessible to students with modest mathematical backgrounds, this is the perfect introductory biostatistics text for undergraduates and graduates in various fields of public health. Features: Illustrative, relevant examples and exercises incorporated throughout the book. Answers to odd-numbered exercises provided in the back of the book. (Instructors may requests answers to even-numbered exercises from the publisher. Chapters are intentionally brief and limited in scope to allow for flexibility in the order of coverage. Equal attention is given to manual calculations as well as the use of statistical software such as StaTable, SPSS, and WinPepi. Comprehensive Companion Website with Student and Instructor's Resources.