Biocompatible Superparamagnetic Ferrite Nanoparticles For Treatment Of Cancer By Hyperthermia

Biocompatible superparamagnetic ferrite nanoparticles are a type of nanotechnology that has shown great promise in the treatment of cancer by hyperthermia. These nanoparticles are typically composed of iron oxide and are superparamagnetic, meaning that they exhibit strong magnetic properties only when exposed to an external magnetic field. One of the key advantages of these nanoparticles is their biocompatibility, which means that they are non-toxic and do not harm healthy cells in the body. In cancer treatment, these nanoparticles can be designed to specifically target tumor cells, allowing for a more targeted and effective therapy. Hyperthermia treatment involves heating the tumor cells to temperatures above normal body temperature, which causes the cancer cells to die. The superparamagnetic properties of these nanoparticles make them particularly effective for this purpose, as they can be easily heated by exposure to an alternating magnetic field, thereby selectively killing cancer cells while sparing healthy cells. Furthermore, these nanoparticles can also be used for drug delivery, allowing for targeted delivery of chemotherapy agents directly to tumor cells. Overall, biocompatible superparamagnetic ferrite nanoparticles show great potential in the development of new and innovative cancer therapies. The word "nanomaterials" consists of two words i.e. nano and material. The size of materials whose dimensions are equal or less than 100 nm is said to be nanomaterial. These materials have been the subject of numerous investigations in the past two decades due to their unique properties and have a technological impact on future generation devices. It has been known that materials exhibit some remarkable properties at nanoscale those are different from its macro-scale size. There is a drastic change in physical, chemical, magnetic, electrical, optical, electronic, and mechanical properties which are further size-dependent. This happens due to unusual properties at nanoscale viz., large surface to volume ratio of atoms, quantum confinement, high chemical reactivity, presence of dangling bonds.

Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.

This book edited by leading experts focuses on the foundation of ferrite materials since inception to its contemporary scenario including their vast applications. The contents range from the basic physics and chemistry of ferrites to its applications in telecommunication, SAR reduction, EMI shielding, hyperthermia treatment, and water decontamination. It also focuses on ferrite nanoparticles for sensing application, energy-storage applications, antimicrobial applications, corrosion protection applications, among others. This book is a useful reference to those in academia and industry.

This book highlights cutting-edge studies in the development of cell-inspired biomaterials and synthetic materials that manipulate cell functions and provide the next generation with contemporary tools for treating complex human diseases. It explores the convergence of synthetic materials with cell and molecular biology and surveys how functional materials, when patterned with spatial and temporal precision, can be used effectively to maintain cell proliferation and phenotype in vitro, to trigger specific cell functions, and to redirect cell-fate decisions. Human stem cells are a frequently discussed subject in this book. This is an ideal book for students, cell biologists, researchers interested in interdisciplinary research, and biomedical engineers. This book also: Highlights successfully developed technologies in cell engineering that make possible new therapeutic development for previously untreatable conditions Covers topics including bio-inspired micro patterning, DNA origami technology, synthetic NOS inspired by compartmentalized signaling in cells, and light-induced depolarization of the cell membrane Illustrates in detail the use of stem cells and synthetic scaffolds to model ethically sensitive embryonic tissues and organs

Magnetic nanoparticles (MNPs) have many applications in the biomedical field because of their non-toxicity, high chemical stability, and biocompatibility. They are used in DNA or protein separation, hyperthermia, tissue engineering, magnetic resonance imaging, cancer therapy, drug delivery, bone and dental repair, biosensors, etc. The book focuses on magnetic nanoparticles and coated nanoparticles (ferrites nanoparticles, bimetallic-magnetic nanoparticles, magnetic fluid); their synthesis, characterization, and in vivo or in vitro biomedical applications. Keywords: Iron Oxide Magnetic Nanomaterials, Magnetic Spinel Ferrite Nanoparticles, Magnetic Oxide Nanoparticles, Ferromagnetic Nickel Nanostructures, Cobalt Ferrite with Niobium Pentoxide, Hyperthermia, Oncologic Magnetic Thermotherapy, Cancer Therapy, Cancer Diagnosis, Drug Delivery. Immune System Related Diseases.

This book delves into the methods of synthesis and functionalization of superparamagnetic materials, offering a deep understanding of their properties and applications. It explores the behavioral study of these materials and provides valuable insights into their diverse applications across various fields. A dedicated section focuses on in vitro and in vivo assessment, toxicology considerations, and post-application aspects. Furthermore, the book summarizes the current development of superparamagnetic materials, including an overview of ongoing clinical trials.

Ferrites are highly interesting high-tech materials. The book covers their classification, structure, synthesis, properties and applications. Emphasis is placed on biomedical applications, degradation of organic pollutants, high frequency applications, photocatalytic applications for wastewater remediation, solar cell applications, removal of organic dyes and drugs from aquatic systems, and the synthesis of hexagonal ferrites. Keywords: Ferrite, Spinel Ferrite Nanoparticles, Biomedical Applications, Ferrite Based Heterojunction, Photocatalytic Degradation of Organic Pollutants, Nickel-Zinc Ferrites, Spinel Ferrite Based Nanomaterials, Water Remediation, Magnetic Nano Particles, Wastewater Treatment, Piezo-Phototronic Effect, Ferrite Based Solar Cells, Aurivillius Based Ceramics, Hexagonal Ferrites.

This book focuses on the applications of bioglasses in the biomedical field. It starts with the history and evolution of bioglasses before moving on to the structure and percolation theory, and lastly investigating their current and potential future applications in various fields including dentistry, tissue engineering, bone regeneration, ophthalmology, and drug delivery. The chapters were written by a team of international experts in the field and will be of great interest not only to material scientists, but also to medical doctors and other health sector professionals.