Biofluid Dynamics

Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage. Clinical applications, extensive worked examples, and numerous end of chapter problems clearly show the applications of fluid mechanics to biomedical engineering situations. A section on experimental techniques provides a springboard for future research efforts in the subject area. Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end of chapter problems All engineering concepts and equations are developed within a biological context Covers topics in the traditional biofluids curriculum, as well as addressing other systems in the body that can be described by biofluid mechanics principles, such as air flow through the lungs, joint lubrication, intraocular fluid movement, and renal transport Clinical applications are discussed throughout the book, providing practical applications for the concepts discussed.

Requiring only an introductory background in continuum mechanics, including thermodynamics, fluid mechanics, and solid mechanics, Biofluid Dynamics: Principles and Selected Applications contains review, methodology, and application chapters to build a solid understanding of medical implants and devices. For additional assistance, it includes a glossary of biological terms, many figures illustrating theoretical concepts, numerous solved sample problems, and mathematical appendices. The text is geared toward seniors and first-year graduate students in engineering and physics as well as professionals in medicine and medical implant/device industries. It can be used as a primary selection for a comprehensive course or for a two-course sequence. The book has two main parts: theory, comprising the first two chapters; and applications, constituting the remainder of the book. Specifically, the author reviews the fundamentals of physical and related biological transport phenomena, such as mass, momentum, and heat transfer in biomedical systems, and highlights complementary topics such as two-phase flow, biomechanics, and fluid-structure interaction. Two appendices summarize needed elements of engineering mathematics and CFD software applications, and these are also found in the fifth chapter. The application part, in form of project analyses, focuses on the cardiovascular system with common arterial diseases, organ systems, targeted drug delivery, and stent-graft implants. Armed with Biofluid Dynamics, students will be ready to solve basic biofluids-related problems, gain new physical insight, and analyze biofluid dynamics aspects of biomedical systems.

Biofluid Mechanics is a throrough reference to the entire field. Written with engineers and clinicians in mind, this book covers physiology and the engineering aspects of biofluids. Effectively bridging the gap between engineers’ and clinicians’ knowledge bases, the text provides information on physiology for engineers and information on the engineering side of biofluid mechanics for clinicians. Clinical applications of fluid mechanics principles to fluid flows throughout the body are included in each chapter. All engineering concepts and equations are developed within a biological context, together with computational simulation examples as well. Content covered includes; engineering models of human blood, blood rheology in the circulation system and problems in human organs and their side effects on biomechanics of the cardiovascular system. The information contained in this book on biofluid principles is core to bioengineering and medical sciences. Comprehensive coverage of the entire biofluid mechanics subject provides you with an all in one reference, eliminating the need to collate information from different sources Each chapter covers principles, needs, problems, and solutions in order to help you identify potential problems and employ solutions Provides a novel breakdown of fluid flow by organ system, and a quick and focused reference for clinicians

Biofluid mechanics is the study of a certain class of biological problems from a fluid mechanics point of view. Biofluid mechanics does not involve any new development of the general principles of fluid mechanics but it does involve some new applications of the method of fluid mechanics. Complex movements of fluids in the biological system demand for their analysis professional fluid mechanics skills.

Designed for senior undergraduate or first-year graduate students in biomedical engineering, Biofluid Mechanics: The Human Circulation, Second Edition teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition has been extensively revised and updated. New to the Second Edition Improved figures and additional examples More problems at the end of each chapter A chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas Drawing on each author’s experience teaching courses on cardiovascular fluid mechanics, the book begins with introductory material on fluid and solid mechanics as well as a review of cardiovascular physiology pertinent to the topics covered in subsequent chapters. The authors then discuss fluid mechanics in the human circulation, primarily applied to blood flow at the arterial level. They also cover vascular implants and measurements in the cardiovascular system.

Improve Your Grasp of Fluid Mechanics in the Human Circulatory System_and Develop Better Medical Devices Applied Biofluid Mechanics features a solid grasp of the role of fluid mechanics in the human circulatory system that will help in the research and design of new medical instruments, equipment, and procedures. Filled with 100 detailed illustrations, the book examines cardiovascular anatomy and physiology, pulmonary anatomy and physiology, hematology, histology and function of blood vessels, heart valve mechanics and prosthetic heart valves, stents, pulsatile flow in large arteries, flow and pressure measurement, modeling, and dimensional analysis.

Biofluid mechanics is the study of a certain class of biological problems from the viewpoint of fluid mechanics. Though biofluid mechanics does not involve any new development of the general principles of fluid mechanics, it does involve some new applications of its methods. Complex movements of fluids in the biological system demand for an analysis achievable only with professional fluid mechanics skills, and this volume aims to equip readers with the knowledge needed. This second edition is an enlarged version of the book published in 1992. While retaining the general plan of the first edition, this new edition presents an engineering analysis of the cardiovascular system relevant to the treatment of cardiovascular diseases and combines engineering principles. Included in the material of this volume are: the emerging interdisciplinary field of tissue engineering, which deals with the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain and improve tissue function, and cellular and molecular bioengineering, which involves the mechanical, electrical and chemical processes of the human cell and tries to explain how cellular behaviour arises from molecular-level interactions. The added material in this edition is specifically designed for biomedical engineering professionals and students, and looks at the important applications of biofluid mechanics from an engineering perspective. Contents:IntroductionCirculatory Biofluid MechanicsBlood Rheology: Properties of Flowing BloodModels of Biofluid FlowsNon-Newtonian FluidsModels for Other FlowsFluid Mechanics of Heart ValvesComputational Biofluid MechanicsTissue EngineeringCellular Engineering Readership: Physiologists, Biophysicists, Biomathematicians and Bioengineers. Keywords:Haemodynamics;Modelling of Blood Flows;Blood Rheology;Non-Newtonian Fluids;Oxygen Transport in the Blood Vessel;Fluid Flow in Kidneys;Peristaltic Flow;Laminar and Turbulent Flow;Fluid Mechanics of Heart Valves;Computational Fluid Mechanics;Tissue Engineering;Cellular Engineering Review of the First Edition: "The book is well presented and clearly written ... presents a useful first introduction to the area and could form an excellent base for a graduate course on this topic." Mathematical Reviews

"The Application of Biofluid Mechanics: Boundary Effects on Phoretic Motions of Colloidal Spheres" focuses on the phoretic motion behavior of various micron- to nanometer-size particles. The content of this book is divided into two parts: one on the concentration gradient-driven diffusiophoresis and osmophoresis, and one on thermocapillary motion and thermophoretic motion driven by temperature gradient. Diffusiophoresis and osmophoresis are mainly used in biomedical engineering applications, such as drug delivery, purification, and the description of the behavior of the immune system; thermocapillary motion and thermophoretic motion are applied in the field of semiconductors as well as in suspended impurities removal. The book also provides a variety of computer programming source codes compiled using Fortran for researchers' future applications. This book is intended for chemical engineers, biomedical engineers and scientists, biophysicists and fundamental chemotaxis researchers. Dr. Po-Yuan Chen is an Assistant Professor at the Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.