Case Studies In Immunology Factor I Deficiency

This book presents a case history of a patient with deficiency of the C8 complement component, to illustrate essential points about the mechanisms of immunity and to explain some of the immunological problems often seen in the clinic. It is helpful for medical and pre-medical students.

This case study is about a 25-year-old male admitted into hospital for the 28th time. He was later diagnosed with a genetic deficiency in factor I that were instrumental in deciphering the mechanism of activation of the alternative pathway of complement activation important in innate immunity.

This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.

Case Studies in Immunology, Seventh Edition is intended for medical students and undergraduate and graduate students in immunology. It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms o

Case Studies in Immunology, Fifth Edition cites major topics of immunology as the background to a selection of real clinical cases that serve to reinforce and extend the basic science. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. As well as being a valuable review aid, Case Studies in Immunology introduces in a clinical setting the major common disorders of immunity, including hypersensitivity types I-IV and autoimmune disorders such as lupus and multiple sclerosis. It also describes and explains the consequences of some of the most important immune deficiencies. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the disease or disorder. An end-of-case summary, questions, and discussion points finish each case. Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway's Immunobiology, Seventh Edition (ISBN 0-8153-4123-9) and The Immune System, Third Edition (ISBN 0-8153-4146-8).

26 real-life cases illustrate the applications of basic immunology in clinical settings May be utilized alone or as a companion to Immunology: A Short Course, 7th Edition by Richard Coico and Geofftry Sunshine (ISBN 9781118396919) Each case study is introduced by clearly written descriptions of the major immunological disorders Full colour photographs and illustrations complement complete presentation of real data Includes complete set of problems and discussion questions for each chapter

This case study is about a 6-year-old boy with recurrent pneumococcal meningitis. It provides information on an inability of the innate immune system to detect pathogen presence, and the sequencing of DNA for the IRAK4 gene that revealed a homozygous nonsense mutation within the kinase domain.

This book presents a case history of a patient with MHC class I deficiency, to illustrate essential points about the mechanisms of immunity and to explain some of the immunological problems often seen in the clinic. It is helpful for medical and pre-medical students.