Clinical Trials In Neurology
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Clinical Trials in Neurology
Author | : Roberto J. Guiloff |
Publsiher | : Springer Science & Business Media |
Total Pages | : 537 |
Release | : 2013-03-14 |
Genre | : Medical |
ISBN | : 9781447137870 |
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Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.
Clinical Trials in Neurology
Author | : Bernard Ravina,Michael McDermott |
Publsiher | : Cambridge University Press |
Total Pages | : 387 |
Release | : 2012-04-12 |
Genre | : Medical |
ISBN | : 9780521762595 |
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Comprehensive book that suggests ways to improve the efficiency of clinical trials and the development of interventions in the neurosciences.
Controlled Clinical Trials in Neurological Disease
Author | : Roger J. Porter,Bruce S. Schoenberg |
Publsiher | : Springer Science & Business Media |
Total Pages | : 447 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9781461314950 |
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The evaluation of the efficacy and safety of a clinical tool, be it a diagnostic technique, a preventive methodology, or a therapeutic intervention, is an im portant responsibility of physicians. The history of medicine is characterized by the authoritarianisms of teachers and of organizations giving way to the clinical experience of physicians; authoritarian dictum was replaced by case report and then by case series. As physicians learned to substitute the analysis of data for the inconsistencies of dictums and anecdotes, the problems of the case series as an investigative tool became more evident: patient selection criteria, measurements of outcome, significance of results, and extrapolation of conclusions to the community of patients. In response to these issues, the methodology of the controlled clinical trial has evolved and with it the instru ments of study design and of biostatistics as aids to study design and data analysis. The medical - surgical armamentarium has evolved from being dependent solely upon the observations and conclusions of a skilled clinician to being constructed upon the systematic collection and evaluation of data by a team of skilled clinicians and their statistical colleagues: this is the controlled clinical trial. During the past two decades, the evaluation of clinical approaches to pre vention and therapy has become particularly important to clinicians concerned with nervous system dysfunction. There has been and continues to be an explosion of information from the basic neurosciences and from the applica tion of biotechnology to the nervous system.
Neuroscience Trials of the Future
Author | : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders |
Publsiher | : National Academies Press |
Total Pages | : 111 |
Release | : 2016-11-07 |
Genre | : Medical |
ISBN | : 9780309442589 |
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On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.
The Right Therapy for Neurological Disorders
Author | : E. Beghi,G. Logroscino |
Publsiher | : Karger Medical and Scientific Publishers |
Total Pages | : 168 |
Release | : 2016-07-26 |
Genre | : Medical |
ISBN | : 9783318058659 |
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Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.
50 Studies Every Neurologist Should Know
Author | : David Y. Hwang,David M. Greer,Michael E. Hochman |
Publsiher | : Oxford University Press |
Total Pages | : 378 |
Release | : 2016 |
Genre | : Medical |
ISBN | : 9780199377527 |
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'50 Studies Every Neurologist Should Know' presents summaries and analyses of clinical trials that have shaped the current practice of neurology. Every subspecialty is covered, with special emphasis on neurocritical care and vascular neurology.
Methods in Clinical Trials in Neurology
Author | : Rudy Capildeo,J.M. Orgogozo |
Publsiher | : Springer |
Total Pages | : 324 |
Release | : 1988-06-18 |
Genre | : Medical |
ISBN | : 9781349089437 |
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Clinical Trials in Neurology
Author | : Bernard Ravina |
Publsiher | : Unknown |
Total Pages | : 388 |
Release | : 2012 |
Genre | : Clinical trials |
ISBN | : 1139379445 |
Download Clinical Trials in Neurology Book in PDF, Epub and Kindle
Comprehensive book that suggests ways to improve the efficiency of clinical trials and the development of interventions in the neurosciences.