Cytopathology Of Soft Tissue And Bone Tumors

Soft Tissue Cytopathology by Anil V. Parwani, MD, PhD and Walid E. Khalbuss, MD, PhD,will fulfill the need for an easy-to-use and authoritative synopsis of soft tissue cytopathology. This volume, part of the Essentials in Cytopathology book series, fits into the lab coat pocket and is ideal for portability and quick reference. Each volume in the series is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. Anil V. Parwani, MD, PhD, is Associate Professor of Pathology at the University of Pittsburgh Medical Center - Shadyside Hospital, Pittsburgh, Pennsylvania. Walid E. Khalbuss, MD, PhD, is Associate Professor of Pathology at the University of Pittsburgh Medical Center - Shadyside Hospital, Pittsburgh, Pennsylvania.

Fine-needle aspiration cytology (FNAC) has been commonly used to follow up on previously treated sarcomas or to confirm soft tissue and bone metastases of carcinomas, melanomas or lymphomas. Its role as the first-line approach in the diagnosis of primary soft tissue and bone tumors has increased due to progress of less invasive diagnostic procedures and the growing availability of diagnostic ancillary tests. This comprehensive and richly-illustrated volume presents cytomorphology of all common neoplastic soft tissue and bone lesions but also of rare tumors largely described in case reports. Key points for cytological features, differential diagnosis, and the use of ancillary tests are discussed and illustrated in order to facilitate the diagnostic work-up in FNA samples. The volume is organized on the basis of the most recent WHO classification used in surgical pathology in order to provide a practical guide for modern cytologic diagnosis of surgical soft tissue and bone pathology. It is aimed mainly at surgical pathologists and cytopathologists, but also at orthopedic surgeons and clinical oncologists.

Cytopathology of Bone and Soft Tissue Tumors provides the practicing pathologist with a single reference for describing and illustrating the cytologic features of musculoskeletal tumors. Using fine-needle aspiration (FNA), the approach of this work is encyclopedic: both relatively common and relatively rare lesions are depicted. It is expected that Cytopathology of Bone and Soft Tissue Tumors will serve to widen the usage of the FNA technique which can: substantially decrease patient morbidity; lessen the complications that arise due to other biopsy techniques; and shorten the time as well as expense required for diagnosis. The chapters on soft tissue lesions are organized by direction of differentiation. Each chapter documents both the common and uncommon lesions within the tissue group. Summaries of clinical findings are given along with the histopathologic and cytologic description. Key diagnostic points (in tabular form) and a discussion of the differential diagnosis complete each section. The section on skeletal lesions is organized along predominant cell type seen in smears. This approach facilitates grouping of lesions into diagnostically useful categories, allowing the pathologist faced with an unfamiliar lesion to rapidly access the portion of the text most useful for differential diagnosis. Within each chapter, the organization is similar to that within the soft tissue chapters. The introduction discusses technical concerns, limitations of the technique, and a diagnostic approach in both tabular and narrative form. Information on grading of soft tissue sarcomas completes the introduction.

PLEASE NOTE: Text has been accidentally deleted from page 54 of this book. Please refer to the corrigenda (PDF file) posted on the Stylus Publishing web site or email [email protected] for an updated, printable page. ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. Since the previous edition, there have been changes based on recent molecular and genetic information, with impact on clinical practice.

This book is a visually rich resource for pathologists who encounter the field of bone and soft tissue lesions. The traditional histologic pictures are supplemented with numerous illustrations of imaging findings, cytology, and molecular and cytogenetic information. Unlike a traditional textbook, this book provides a pictorial survey arranged in a “pattern oriented” approach, similar to the working method used in actual daily practice. Original artwork illustrating the molecular underpinnings of sarcomagenesis provide a valuable introduction to this complex area and are an especially useful feature. The authors of this work are both expert surgical and cytopathologists that actively practice in multidisciplinary sarcoma centers and are experienced teachers in this complex field of diagnostic pathology.

In the last few years, the primary diagnosis of soft tissue tumours has emerged as an important new target for fine needle aspiration (FNA). The purpose of this book is to facilitate the cytological evaluation of FNA smears from soft tissue tumours and to suggest cytological criteria for histotype diagnoses. Its primary aim is to describe and illustrate not only the most common types but also those rare tumours where cytological features have been largely described in case reports and in small series. The diagnostic use of ancillary methods is discussed and illustrated, and, in order to facilitate the diagnostic work-up in FNA samples, smears are also classified according to their principal microscopic patterns. The selection of entities presented, their diagnostic features and differential diagnostic considerations are mainly based on the experience with FNA in the primary diagnosis of soft tissue tumours in patients referred to the Musculoskeletal Tumour Centre at the University Hospital in Lund, Sweden over the last 30 years. The illustrations have mainly been culled from cases in the files of the Department of Pathology and Cytology, Lund University Hospital. Soft tissue tumours are relatively rare and often difficult to correctly diagnose in fine needle aspirates. Therefore, this publication should be welcomed by all cytopathologists involved in the FNA diagnosis of tumours as a valuable addition to their benchside textbooks.