Demyelinating Disorders Of The Central Nervous System In Childhood

This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.

Although multiple sclerosis and other disorders of myelin formation and repair are most commonly associated with adults, they can also occur in infants, children and adolescents. Up to 5 percent of those with MS experience symptoms before the age of 18, and the number of cases diagnosed is rising. There is a lack of awareness about these diseases in childhood, however, even amongst pediatric neurologists and MS specialists. Demyelinating Disorders of the Central Nervous System in Childhood provides comprehensive coverage of these diseases, highlighting throughout the differences between management in childhood and in adults. With sections dedicated to the diagnosis, course, treatment and biology of pediatric MS, detailed chapters on other childhood demyelinating diseases, including acute disseminated encephomyelitis, optic neuritis, acute complete transverse myelitis and neuromyelitis optica, are also provided. Essential reading for pediatric neurologists and MS specialists, this book will also be valuable reading for adult neurologists and pediatricians.

Provides comprehensive coverage of pediatric multiple sclerosis and similar conditions, highlighting differential diagnosis, investigation and management.

This issue reviews the state of the art in pediatric demyelinating diseases. Articles cover topics on childhood transverse myelitis, neuromyelitis optica, multiple sclerosis, acute demyelinating encephalopathy, and more.

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Inflammatory disorders of the nervous system, although individually uncommon, collectively make up 10-20% of acute paediatric neurology presentations and many are potentially treatable. Research into them is lagging behind adult research, but better diagnosis and often simple treatments could lead to substantial clinical benefit and reduction in long-term disability. This book provides a detailed and comprehensive summary of the childhood diseases that are, or are likely to be, caused by the immune system. The authors not only describe these disorders and their treatments comprehensively, helping pediatricians and pediatric neurologists to improve their understanding and recognition of the conditions, but also highlight recent and exciting developments that will be of considerable importance in the future.

Neurological Problems in Childhood focuses on developmentally deviating and disabled children. This book provides an explicit and a well-balanced analyses and compilations of signs and symptoms of neurological problems, and how to deal with them in the examination room. Organized into 14 chapters, this book begins with an overview of the process of neurological examination relevant to the neonate and the infant. This text then discusses the significance of obtaining a careful description of symptoms and the need to question the child as well as the parents. Other chapters consider the variety of disorders that are genetically determined. This book discusses as well the abnormalities at birth due to faults in the early growth and development of the body. The final chapter deals with the advances in the field of genetics that contribute to the management of neurological diseases. This book is a valuable resource for pediatric neurologists, general pediatricians, and public health physicians.

A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.